HsaINT0185322 @ hg38
Intron Retention
Gene
ENSG00000148516 | ZEB1
Description
zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642]
Coordinates
chr10:31520126-31524113:+
Coord C1 exon
chr10:31520126-31521936
Coord A exon
chr10:31521937-31523932
Coord C2 exon
chr10:31523933-31524113
Length
1996 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
3' ss Seq
TCACACCTTTCTCCCTCTAGGAT
3' ss Score
13.06
Exon sequences
Seq C1 exon
GAGAGAAGCCATATGAATGCCCAAACTGCAAGAAACGCTTTTCCCATTCTGGCTCCTATAGCTCACACATAAGCAGTAAGAAATGTATCAGCTTGATACCTGTGAATGGGCGACCAAGAACAGGACTCAAGACATCTCAGTGTTCTTCACCGTCTCTTTCAGCATCACCAGGCAGTCCCACACGACCACAGATACGGCAAAAGATAGAGAATAAACCCCTTCAAGAACAACTTTCTGTTAACCAAATTAAAACTGAACCTGTGGATTATGAATTCAAACCCATAGTGGTTGCTTCAGGAATCAACTGTTCAACCCCTTTACAAAATGGGGTTTTCACTGGTGGTGGCCCATTACAGGCAACCAGTTCTCCTCAGGGCATGGTGCAAGCTGTTGTTCTGCCAACAGTTGGTTTGGTGTCTCCCATAAGTATCAATTTAAGTGATATTCAGAATGTACTTAAAGTGGCGGTAGATGGTAATGTAATAAGGCAAGTGTTGGAGAATAATCAAGCCAATCTTGCATCCAAAGAACAAGAAACAATCAATGCTTCACCCATACAACAAGGTGGCCATTCTGTTATTTCAGCCATCAGTCTTCCTTTGGTTGATCAAGATGGAACAACCAAAATTATCATCAACTACAGTCTTGAGCAGCCTAGCCAACTTCAAGTTGTTCCTCAAAATTTAAAAAAAGAAAATCCAGTCGCTACAAACAGTTGTAAAAGTGAAAAGTTACCAGAAGATCTTACTGTTAAGTCTGAGAAGGACAAAAGCTTTGAAGGGGGGGTGAATGATAGCACTTGTCTTCTGTGTGATGATTGTCCAGGAGATATTAATGCACTTCCAGAATTAAAGCACTATGACCTAAAGCAGCCTACTCAGCCTCCTCCACTCCCTGCAGCAGAAGCTGAGAAGCCTGAGTCCTCTGTTTCATCAGCTACTGGAGATGGCAATTTGTCTCCTAGTCAGCCACCTTTAAAGAACCTCTTGTCTCTCCTAAAAGCATATTATGCTTTGAATGCACAACCAAGTGCAGAAGAGCTCTCAAAAATTGCTGATTCAGTAAACCTACCACTGGATGTAGTAAAAAAGTGGTTTGAAAAGATGCAAGCTGGACAGATTTCAGTGCAGTCTTCTGAACCATCTTCTCCTGAACCAGGCAAAGTAAATATCCCTGCCAAGAACAATGATCAGCCTCAATCTGCAAATGCAAATGAACCCCAGGACAGCACAGTAAATCTACAAAGTCCTTTGAAGATGACTAACTCCCCAGTTTTACCAGTGGGATCAACCACCAATGGTTCCAGAAGTAGTACACCATCCCCATCACCTCTAAACCTTTCCTCATCCAGAAATACACAGGGTTACTTGTACACAGCTGAGGGTGCACAAGAAGAGCCACAAGTAGAACCTCTTGATCTTTCACTACCAAAGCAACAGGGAGAATTATTAGAAAGGTCAACTATCACTAGTGTTTACCAGAACAGTGTTTATTCTGTCCAGGAAGAACCCTTGAACTTGTCTTGCGCAAAAAAGGAGCCACAAAAGGACAGTTGTGTTACAGACTCAGAACCAGTTGTAAATGTAATCCCACCAAGTGCCAACCCCATAAATATCGCTATACCTACAGTCACTGCCCAGTTACCCACAATCGTGGCCATTGCTGACCAGAACAGTGTTCCATGCTTAAGAGCGCTAGCTGCCAATAAGCAAACGATTCTGATTCCCCAGGTGGCATACACCTACTCAACTACGGTCAGCCCTGCAGTCCAAGAACCACCCTTGAAAGTGATCCAGCCAAATGGAAATCAG
Seq A exon
GTAAAAAATAACCTCCATCCTGAACCTGGCTAGTAATATGCTATTTGACTAATTTCAATTAACTTTGTCTAATAAATATCAGTCCCGTAGAGCCAACTAGATTATTACAAACTGTCATTTTTAAAAGGATCAATGTTTGCTTTAACTTTTCTGGCATGATGTCTTCAGTTGGTTGTTTGCTAATCCAGGGTATTGTTACCAGCTTAAAGTTTGAAATGCTATTCTACTGAAAGATGATTTTTAAGTCCCAGCTAAAAACCTGTTTGAAGTTAGAAATCAAAAAACAAAATTGAAATACTCGCTAATTGGGTTTCTGTTTTTATAGCTAAATTCCTAAAATTAGTAATAGTTTCTGCCTTGATTATGGTCATTAATTAATGAAAATATGTTCCCATTCACAGGTTCATACCAGGCAAACTTATCTATCACTTTTATATACTAATACATCTGTTTATAAAAGGTTTTAATTAAATAAACAGGAATGAAGTATACAAAGAACGCATCTTGTGAATTTACTGATCATTTTATGAACTGTGCATAAACAGTGTTCAGTCATAATGTATATGAGGAAGTGTGGCTGTGAACCTAAAAATACATATGCATTTTCCTCCTTAACTATCACAGTGTTTACCACAACAGTGTTTATTCTGTCCAGGAAGAACCCTTGAACTGGTCTTACCCCAAAATCCACAATAGTTTTGGATAGAGCTATTGTATGCCTCATTGTCCAGACTTTTTCCATGTCACTGATGTTGATGTTTTCCCATTTTTTCCATCAATTTCTGATGGAATCAAATGAATACTAGAGACAAATTTGATATTTTATGCAAATATTTTCTATAAGTATAATAATTTCAATATCCTGCTCAAACTTGTATTTGCTGCTTTTGTTTTCCCTTAAATATTGCTATTGATTGGGTTTCCTGTAATTGTGATAACTCTTGAAAAAAAGTTCTTACGTGATCATTGAATTCCTCTAAATTTTTAGTGTACAGAACACTTTGCATGCCTTTGAATAGAAAAAGAGCCATCCTTAGCATTTCATAGACTCACGTGTCACGTGACTAGATCAAGTAGCAGTGAAAGTAGAATCAAGTTACTTCAGCACCAGGGCCACTCACAAATGACAGGGACAAATGGCTGCACCTCTCTTGCCTCATAGAGCCATAAGAAATGTTGTGAAAAACCTTCAACTTTTAGAAAATGTGTGGGTTTGAGGCAATGGCGTGGAACACTCTAGATAAGGTAGGAAGATCTTAGGGGACCCAGTTCCACAACAGGCTCCCTGCAGGGTTATTTGGCTTACATAAGAACGTGCTGCCCAAAATTATCTCCATGAGACTGCCTGGAGTTTCTAAAGGTTCATTTTGATTAGCAATTATTTCTGTTAAAAAGATAGACCCTCCTGCATTGTTTTTCCATCTTGCTCCTTAGACAAGTGGTAGAGCACACCTCTCTCTTTTCAAGGAGACCGTGGAGGTTAAAGAACCCTGAAGTTCTGGAGGATACAATTGAAAGACCAGGTTTTAAAAATAGAATGTTAGCTTTTGCTTAGTGAAACCCAGAATGAGAAAAATGAAGGCAAAAGATGCAGTTAGTAATGAGCGATTAATTAGCAAACTAATAAGTTAAAACCTTCTGCAAATTTCTCGTAAAGTAATGATTCACATGAAACTAGGTAAACTCTGTTACTATATATTTTACATGCTTTCTTTTCGGTGTCCTTGCTTTCTTTCCAGTACCAGTTGAGTATATGTCTTTGCTATGGTTTTGACTGTGTTATCCCCAACCTCACTCTTGTCTTTGTCATCTCCACCTGTGATCTGGCCCCACCCTTGGGGCACATGTGCAGTGAAGATCAGTGTGCTTGCTTTGGTCAAGTCCTTGAAAGTATAAAAGTATAAGTTAAAGTAGTTCTTTATCTCATGCTTTTATGTATATCTCTTGTTTATCTTTTAATGTTAAATTACATTTTCTCACACCTTTCTCCCTCTAG
Seq C2 exon
GATGAAAGACAAGATACTAGCTCAGAAGGAGTATCAAATGTAGAGGATCAGAATGACTCTGATTCTACACCGCCCAAAAAGAAAATGCGGAAGACAGAAAATGGAATGTATGCTTGTGATTTGTGTGACAAGATATTCCAAAAGAGTAGTTCATTATTGAGACATAAATATGAACACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148516:ENST00000437844:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.494 A=NA C2=0.623
Domain overlap (PFAM):
C1:
PF134651=zf-H2C2_2=PD(57.7=2.5),PF0004624=Homeobox=WD(100=8.3)
A:
NA
C2:
PF134651=zf-H2C2_2=PU(38.5=16.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGAGCCACAAAAGGACAGTTG
R:
TGGGCGGTGTAGAATCAGAGT
Band lengths:
354-2350
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains