MmuINT0178367 @ mm10
Intron Retention
Gene
ENSMUSG00000024238 | Zeb1
Description
zinc finger E-box binding homeobox 1 [Source:MGI Symbol;Acc:MGI:1344313]
Coordinates
chr18:5766221-5770564:+
Coord C1 exon
chr18:5766221-5768025
Coord A exon
chr18:5768026-5770383
Coord C2 exon
chr18:5770384-5770564
Length
2358 bp
Sequences
Splice sites
5' ss Seq
CAGGTTAGT
5' ss Score
8.02
3' ss Seq
AATCTTCTTTTTCCACTTAGGAT
3' ss Score
9.45
Exon sequences
Seq C1 exon
GAGAGAAGCCATACGAATGCCCGAACTGCAAGAAACGGTTTTCCCATTCTGGCTCCTATAGCTCACATATAAGCAGTAAGAAGTGTATTAGCTTGATGCCTGTGAATGGCAGGCCTAGATCAGGACTCAAGACATCTCAGTGTTCCTCGCCATCTCTTTCGACATCACCAGGCAGTCCCACACGCCCACAGATACGACAGAAGATAGAGAATAAACCCCTTCAAGAACCGCTTTCTGTAAACCAAATCAAAACTGAACCTGTGGATTATGAGTTCAAACCCATAGTGGTTGCTTCAGGAATCAACTGTTCAACCCCTTTACAAAATGGGGTTTTTAGCAGTGGTGGCCAATTGCAGGCAACCAGTTCTCCTCAGGGTGTGGTGCAAGCCGTTGTTCTGCCAACAGTTGGTTTGGTATCTCCCATAAGTATCAACTTAAGTGACATTCAGAATGTACTTAAAGTGGCTGTAGATGGTAACGTAATACGACAAGTCTTGGAGACTAATCAAGCCAGTCTTGCATCCAAAGAGCAAGAAGCAGTGAGTGCTTCGCCCATCCAGCAGGGTGGCCATTCTGTCATTTCTGCCATCAGTCTTCCTTTAGTTGATCAGGATGGAACAACCAAAATCATCATCAACTACAGTCTTGAGCAGCCCAGTCAACTTCAGGTTGTTCCCCAGAATTTAAAGAAAGAAATCCCAGCCCCTACAAACAGCTGCAAAAGTGAGAAGTTACCAGAAGACCTTACTGTCAAATCAGAAACGGACAAAAGCTTTGAGGGGGCCAGGGATGATAGCACTTGCCTTCTGTGTGAGGACTGCCCAGGGGACCTCAATGCACTTCCAGAACTAAAGCACTATGACCCAGAGTGCCCTGCTCAGCCTCCACCCCCTGCCCCAGCCACCGAGAAGCCAGAGTCCTCTGCTTCATCAGCTGGAAACGGAGATTTGTCTCCCAGTCAGCCACCTTTAAAGAACCTTCTGTCACTCTTGAAAGCCTACTATGCTCTGAACGCGCAGCCAAGCACAGAAGAGCTCTCAAAGATCGCCGATTCTGTGAACCTACCGCTGGATGGAGTTAAAAAGTGGTTTGAAAAGATGCAAGCTGGACAGATTCCAGGACAGTCTCCTGACCCCCCTTCTCCTGGAACCGGGTCAGTAAACATACCTACAAAAACCGATGAGCAGCCTCAACCTGCGGATGGAAATGAGCCCCAGGAAGACAGCACACGCGGACAGAGTCCTGTCAAGATAAGGAGCTCTCCGGTTTTACCTGTAGGATCAGCCATGAACGGTTCCAGAAGCTGCACATCATCCCCATCCCCTCTAAACCTTTGCTCAGCCAGGAACCCGCAGGGTTACTCTTGTGTGGCAGAGGGTGCCCAGGAGGAGCCCCAAGTAGAACCTCTTGATCTCTCACTACCAAAGCAACAGGGAGAGTTACTGGAAAGGTCGACAGTCAGTAGCGTTTACCAGAACAGTGTTTATTCTGTCCAGGAAGAACCCTTGAACTTGTCTTGTGCAAAAAAGGAACCACAAAAGGACAGCTGTGTTACAGACTCAGAACCAGTTGTAAATGTAGTCCCACCAAGTGCCAACCCCATAAACATTGCTATTCCTACAGTCACTGCCCAGTTACCCACAATCGTGGCCATTGCTGACCAGAACAGTGTTCCATGTTTAAGAGCACTGGCCGCCAACAAGCAGACTATTCTGATTCCCCAAGTGGCATATACATATTCAGCTACTGTGAGCCCTGCCGTGCAGGAGCCGCCAGTGAAGGTGATCCAGCCAAACGGAAACCAG
Seq A exon
GTTAGTAAAGCATTAACCTAAGTTTTTTTAGTGAAGAAATCTCTGTCTCTGTAGAATCAACCAGATTGTTACAGCTGCCATGTTTAAATGGAACTTATGGGTTTGCTTTCCTTGCATGGCAGGATACCTTCCTTCCCTTGCTACTCAGCTGCCTTAGGGCATCAACCACAGTTGAGAGTGTATTCTCTGAAAACCAGTGCATGAACTCAGCTGGAGACCTGACTGAGCTTAGAAGCATAAGACAAAATGTGTTACTCATTAGTTAGAGTGGTGGTTTTCTAGTTAAATTTTCAGATTGGTGAGTTTCTTCTTTGCTTATGATCACTATTAAACAACCATGTTCCCATTCACCATAAAGCCAAGAAAGGGTTTGCTGGTACTTCGTGTGCCAACTCCTTTGTTAGGAGTTAGGTTAACCTTTGGTTAAACAGAGTATTCTGGAACTCAGATACAGTGTTTGGTTGTAGGTACTCATGAGGTGTGCCTGTGGCCAAGGAGTGCCACACCTCATGAGGCCTGGCTTTGTTTGGTTCTGGGTAGAACTCTGCTGTATTGCTATTTGTTTCTCACTGTCTATCCAGAATCTTCCCATGACACTAGGCTTGATATCGCCACTTTTTCATCAGTCCCTTTAATTGGATCAAATGCCAGAGATGGCTGTTTGATCTTACTGCAGGCACAGCTACAGTTGCTCTGTGTCCTGCTCAGGTTTGCCCTGTGGCCTCCTGTGACTGCCACTCACTCATTGGCATCTCCAGAATTGTAGTAACTCATAAAGAAACCATGCCCATGACTAATGGCACTAGATTTCTGGGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGATGTATACTTGTGTATGGACAGGTGTGTTCACCCATGAGTGTGCATGTAGAGGCCAGAGATTGACAGTGACTGTCTTCCTAATCACTCTAATATTTTGGGGACAGGGTCTCTCCCTGAACCTGGAGCCTACCATTTTGTCTAGACTGGCTGGCCCCACTATCTGCCATCTTCCCAGCCCTTCTTGATACCTTTGAATTTAAAGAAAACAGAGCTTTTACCATTTCAAGTGACTTGGACTATATCAAGAGCTATAAAGTAGAGTCACTTCTACACTGGCAGCTAGTGATAAATGACTGGCTTTGCTTGTCATATCGAGCTTTCAAAAGAACAGAGTCTATGAGACTCTAGGAAAGACCCAAAGGTCATAGGTGACCTAAGTCTTCAAGAGGCTCTCTGCAGGACTATTCCATTGAGAAAAGCGCCTTTTCTGAAAGTGACTTCTCTGAGACCATCTTGAGGTTCTATGTCATGTCTTGTGTATTTTATGAAAATTGTAAGGGTTCTCTTTTACAGACAGCTACTCCTATTTAAAAATCTCAGCCCCTCTCACACTTTTCCTCCTCATTCCAGGGAAAGTATGGACCAAAGCAAATCCCTCTTCGCCAGACCAAGGGAGCTGGTACAAAGGCCTCCAGGATGAAGGACACACTTTAAAGACATTGTCTAAACTATGTCTCAATTCTTAGTGAAACGCAGAATTTTTATGAAAAGCACAGTAAGGGCTGGTGAGATGGCTCAGTGGGTAAGAGCACCCAACTGCTCTTCCGAAGGTCCGGAGTTCAAATCCCAGCAACCACATGGTGACTCACAACCATCCATAACGAGATCTGACTCCCTTTTCTGGAGTGTCTGAAGACAGCTACAGTGTACTTACATATAATAAATAAATAAATCTTAAAAAAAAAAGAAAAAAAGAAAAGCATAGTAAATGATGAATTGGAAATGAGTGGTGAATTATCAAGCTCATTGATTAAACCTTTCTGCAAAGCCACTCTAAAATCATAATTTGCCAGAATAAAGTAAATATGGCTGCTGTCCATCTGATGTCTTCTTCTGGTGGCCTCTCTTTTTGGTACAGTTGAAGAATGTTTTCACTATACCCTTTTCTGTGTTGTTCCCAGCCTCACTTGTGTCTCTCTGGGCCTGTTTGTAGTAAGTACTAGTGCCCCGGGAGCTGTCCGTAGCCACTGTAGTGTGTGCTCGCTGGGCTCAGGTGGAGGGCTTCACATCTAACATGAAATTTCTCTCTTGTGCATCTCTTGACTTTCCTACATTTATTGACTTATTGGCAGTGGGTGCTTTGTGTGCCAGCTCTCACACGTGGAGGTCCGAGGACAACTTGTGGGAGTCAGTTCTCTCCTTTCACCGTGTAGATCCCAGGGATTCAACTCTGCTCATCTTTCTTTGTGGCAAATAGCTTTGTCTGCTGAGCCATCTCAGTGACCTTATCTCTTGGGAATCTTTTTCTTTGACATTTAATCTTCTTTTTCCACTTAG
Seq C2 exon
GATGAAAGACAAGACACTAGCTCAGAAGGAGTCTCCACTGTGGAGGACCAGAATGACTCTGACTCCACGCCACCCAAAAAGAAAACTCGGAAGACAGAGAATGGAATGTATGCATGTGACCTGTGTGACAAGATATTTCAGAAGAGCAGCTCACTGTTGAGACACAAATATGAGCACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024238:ENSMUST00000025081:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.482 A=NA C2=0.623
Domain overlap (PFAM):
C1:
PF134651=zf-H2C2_2=PD(57.7=2.5),PF0004624=Homeobox=WD(100=8.1)
A:
NA
C2:
PF134651=zf-H2C2_2=PU(38.5=16.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types