HsaINT0186588 @ hg19
Intron Retention
Gene
ENSG00000196150 | ZNF250
Description
zinc finger protein 250 [Source:HGNC Symbol;Acc:13044]
Coordinates
chr8:146115318-146115788:-
Coord C1 exon
chr8:146115693-146115788
Coord A exon
chr8:146115460-146115692
Coord C2 exon
chr8:146115318-146115459
Length
233 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGC
5' ss Score
9.88
3' ss Seq
TTTGGTTTTACCTGCAGCAGCCC
3' ss Score
0.38
Exon sequences
Seq C1 exon
CCCCATAGGCTCCTTCAATTTCCGTGATCCTCGGAGTCCCCAGGAGACCAGGTGATGGCAGCAGCCAGACTCCTGCCAGTGCCGGCAGGACCCCAG
Seq A exon
GTAAGCTGTCCCCAGTGCTTATGCAGTGCCCCCAGCCCGAGCCCTGTGGTTCCTTCCGTGCCCCGTAGAGCTCCTAAGAGCAGCCAGAGCGTCACCACATGCCCTGAACTCCGCGGCCCCTTCCCATCACCCACCTCAGCTCACAGAGCCCCCCACTGCCAACTGCTCATGTCACATGTCACATGCACCCACTCCCCATCACAGACATCAGGATTTGGTTTTACCTGCAGCAG
Seq C2 exon
CCCCTGTCGTTCCAGGCCAAGCTGACCTTCGAGGATGTGGCTGTGCTCCTCTCCCAGGATGAATGGGACCGCCTGTGCCCTGCTCAGAGGGGTCTCTACAGAAATGTGATGATGGAAACCTATGGGAATGTAGTCTCATTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000196150-ZNF250:NM_021061:2
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.121 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0135222=KRAB=WD(100=85.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCCATAGGCTCCTTCAATTTCC
R:
CCAATGAGACTACATTCCCATAGGT
Band lengths:
238-471
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)