HsaINT0187283 @ hg19
Intron Retention
Gene
ENSG00000185219 | ZNF445
Description
zinc finger protein 445 [Source:HGNC Symbol;Acc:21018]
Coordinates
chr3:44481262-44491115:-
Coord C1 exon
chr3:44491005-44491115
Coord A exon
chr3:44490232-44491004
Coord C2 exon
chr3:44481262-44490231
Length
773 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
TGTGTTATATTTTTTGTCAGGAG
3' ss Score
6.75
Exon sequences
Seq C1 exon
TGGGACCATTCACCAAACCTGCTCTGATCTCCTGGTTGGAAGCAAGGGAGCCATGGGGCCTGAACATGCAGGCAGCTCAGCCTAAGGGGAATCCAGTTGCTGCTCCTACAG
Seq A exon
GTGAGTTCCAGAGAACCTGCCAGGTCCTGCTCCTCCTGCTTTTACTTTTCTCTTTCTTAAGGTCAGTTACATCACTGGGAATTTACTCCATTGTTTGCTGGAAGGAAGATCTTTAACAGTGTTGGTAAGGGTGCTTGGGCCACTGGGTCTCTTCCATCCTGGCTGGCCTCCGAGAGGTCATTCATTTCCGGCCATGTCTATTCTCCTGTCCCCTTCTCACAGCAGCCCTCTCAATAATAGTTCTTGCCTGCTGGAGGGCTTCACTGTTCCTGTCTTTCACTCACTGATGCTCCTCCTCACTCCTGGCCTGCACTCCTGCTGAACTCCTGTACTCACCCCTTTCTGCTCTTAGGAGCCCTCATCCCACTCCTGTTCTTTCTTTTCTTGGTCCTTCTTTTTGTAATAGGCTGATCTCCAGCCCTTTCAGCCAAGTGCTCCTTGGAGCCCCACCCCTTGGCTTTTGGGTACCTTTCTATAATGCCATGATTTTTCTCCCACTCTGGCTGTTTAACACTTTCTTCTTAATCCTTTTTATTTCCCTGCTGGATGTGACGTCTGCATATCTCTAGCTGCCCTGCCCATCTTGCTTTTCTTCTCCCTTCCCTGTAATCTGGGATAATCTTCCATGTTTTGCCTTATGTTTGACTATTTTATAAAGGTATTGGCAGTCAGGCAAAAGCCTCACCACCCAGACATTTTATTGCCCTTTGGTGCTTTCTGCAGTTCCAAGTATGGGAAAAGAGTACATTCTCTTGTGTTATATTTTTTGTCAG
Seq C2 exon
GAGATGACCTCCAGAGTAAAACAAACAAATTCATCTTAAATCAGGAACCTTTGGAAGAAGCAGAAACCTTAGCTGTGTCATCAGGATGTCCTGCGACAAGTGTTTCTGAGGGAATTGGGCTCAGAGAATCTTTTCAACAGAAGAGCAGGCAGAAGGATCAATGTGAAAATCCCATACAAGTAAGAGTTAAGAAAGAAGAGACCAATTTCAGTCACAGGACAGGAAAAGACTCTGAAGTATCAGGAAGTAATAGTCTTGACTTAAAACATGTTACATATTTGAGAGTTTCTGGAAGAAAGGAATCCCTTAAACATGGCTGTGGCAAACACTTCAGAATGAGTTCACACCACTATGACTACAAGAAATATGGGAAGGGGCTCAGACACATGATTGGGGGCTTCAGCCTACATCAGAGAATTCATAGTGGACTGAAAGGGAACAAAAAGGACGTGTGTGGAAAAGACTTCAGCCTTAGCTCTCATCACCAACGTGGGCAGAGTCTTCACACAGTGGGAGTGTCATTTAAGTGCAGTGACTGTGGAAGGACTTTCAGTCATAGCTCCCATCTTGCGTATCATCAGAGACTTCACACTCAAGAGAAAGCATTTAAATGTAGGGTGTGTGGGAAAGCCTTCCGGTGGAGTTCCAACTGTGCGCGGCATGAGAAAATTCACACTGGAGTGAAGCCTTATAAATGCGATTTATGTGAGAAAGCTTTCCGACGCCTGTCAGCCTACCGTCTGCACCGAGAAACCCATGCTAAGAAGAAATTTCTTGAATTGAATCAGTATAGGGCAGCTCTCACCTACAGCTCAGGGTTTGATCATCATTTGGGAGACCAAAGTGGGGAGAAACTCTTTGACTGCAGCCAGTGCAGGAAATCCTTCCACTGTAAGTCATATGTTCTTGAACATCAAAGGATTCACACCCAGGAGAAGCCCTATAAATGTACCAAATGTAGGAAAACCTTTAGATGGAGATCAAACTTTACTCGTCATATGAGGTTGCATGAGGAGGAAAAATTCTACAAACAAGATGAATGTCGTGAAGGCTTCAGGCAATCTCCTGACTGCAGTCAGCCCCAGGGTGCTCCCGCTGTGGAGAAAACATTTCTGTGTCAGCAGTGTGGGAAAACTTTTACTAGAAAGAAAACTCTCGTTGACCACCAGAGAATTCACACAGGTGAGAAACCTTACCAGTGTAGCGATTGTGGGAAGGACTTTGCCTATAGGTCAGCCTTTATTGTTCATAAGAAGAAGCATGCCATGAAAAGAAAACCTGAGGGCGGGCCATCTTTTAGTCAGGACACAGTGTTCCAGGTTCCTCAGAGCAGTCACTCCAAAGAGGAGCCCTACAAATGCAGCCAGTGTGGCAAGGCCTTCCGCAATCACTCATTCCTCCTCATCCATCAGAGAGTTCACACTGGAGAGAAGCCATATAAGTGCAGGGAGTGTGGGAAAGCCTTCAGATGGAGTTCCAATCTCTACCGACATCAGAGGATTCACTCTCTTCAAAAACAGTATGATTGCCATGAAAGTGAAAAGACTCCAAATGTGGAGCCAAAAATCCTCACTGGTGAGAAACGTTTTTGGTGTCAAGAATGTGGGAAAACCTTTACACGTAAAAGAACCCTTTTAGATCATAAGGGAATACACAGTGGAGAGAAGCGCTATAAATGTAATCTATGTGGGAAATCTTATGATAGAAACTATCGCCTTGTTAACCATCAGAGGATCCACTCTACAGAGAGACCTTTCAAATGTCAGTGGTGTGGGAAAGAGTTCATTGGGAGACATACCCTTTCCAGTCACCAGAGGAAACACACCAGAGCAGCACAGGCTGAACGTAGCCCGCCTGCACGGTCTTCCTCTCAGGACACAAAGTTGAGATTACAGAAGCTAAAACCAAGTGAAGAGATGCCCCTCGAAGACTGCAAAGAAGCTTGCAGCCAGAGCTCCAGGCTCACTGGACTCCAGGACATAAGCATTGGGAAAAAGTGCCACAAATGCAGCATATGTGGGAAAACTTTTAACAAGAGTTCACAACTCATTAGCCACAAGAGATTTCATACTCGAGAGAGGCCCTTCAAATGCAGCAAGTGTGGAAAGACCTTCAGGTGGTCTTCGAACCTGGCTCGGCATATGAAAAACCATATTAGAGATTAGCCTGGGACCTGACAGTGACAGTGGGGGTGGGTTCTCAGTCCCCTGCTAGAGAACCCTTAATTATAGGCATTGTGGAGTAACTTTGATAAAGGGCCCAGCCCTTTCTGTTTTGGAAGCTAGTGACAGAATCCCAAGGATTTGAAAGCTCGGGGAGTCCCCAGCCTGCCTGCTAGGATGTGACGCTGGGGAAGTGCAGCACCATGTCCTTTGGAGCCCTTCTGGAGACTCCGGCCCCTAGGAGTGGCCTCTGCACCATAGCCTGCGGCTCCCCTATTCAGGTCTCCTTCCACAACTCTGAAGAGAGAGACCACTGCCCTTTGTGGTTGGACAGAATATCTGTGGCATCATGGGCTATGGCTGCTGGAAAGGGGCCAGTGGGATCCTAGATTTGTCTTCAAGTTTGGCCTGTGGCCATGCCTATTCTGTTGACTTTAAAAGCAGCAGCATCAAGAACTCCTAGCCTTCCCAAATGCCCCCTGGGGAGTTCTGGCTGGGGCTTCAGCCTTCCTGGCTGGCTTTTGGATATCTGCTAGGGGGTTAGAGTGGTCTCAGCGGCAGGTGGAGGAGAGCAGGATGCTGGGCTCAAGCGCTTGGCGTGTGGATCTCTACCAGTACCCTGTTGCCATCCCCATCCCACAGGCCTGCATAGGCAGCAGCGGTCCATCTGTTTAACAGAAATGTGCTGAGCACTCCCATACACCAGGCGCTGGTGTGTTTGCCAGAGACCCAGCAGGGACCAGAACAGATGAAAATCCTGCCATCTTGGATCTTTACAGATGACAAACAAATGGGATACGCAGTATTCTGGATGGTGATGTGTGTAGTGGACAAAGTGAATCAGAGAAGAGCAGAGGGAGTGCTGGATTGGGAGATCAGTCGTGATTTTAGATAGTCTGGTCAGGGAGGGCCTCAACTGAGAAGGTGAAATGTGAGCAAAGACGTGAAGGAAGCCAGGGAGGTAGCAGGTAGCTCTCTAGGGAGAGTTGCAGGCAGAGGAGATTGGGTCTTGACTGGTGTCCTCAGGAAGGAAGCCCCTGGGATGGAGTGCAGGGAGCCAGCTGGAAGGGAAGGAGAGGGGCCAGGGAGGCCACAGGCCCGGCCATATGAGCATCATGGGTCATTACGGGGGCTTGAGCTGGCTCAGAGGGAGGCAGGGAGCTTTTGGACAATTTTGAGTTGAGGAGTGATGTGGTTTGAATCTGAATTATATTTTATAAGGGTTAACCACAGATCCAAGGACTCAGTAAAAGGGTGAAAGGCTTCTCATGCAGTTAGCCTTGCTGCCAGTTCCCATAAATCAGACTCCTCCCCACTCCGTTTCTGAATTTTCTATAGGATCCTCGGCCTCAGCAGATATAAACGCTTACCATTGTTGTGTTCATGTCTCTAGCCCCTGCACACTGCAGGCCCCTCTCAGCTTCACATACCCCTCTCCATGTATGAGATCTGGTGCTAGCAATCAGATTCAACCCGAAGGAACAAGTGCATGTGCCTGCTGCTCTCAGGAGAAAAGGCAGCCTGTTCTGGGAGGAGCTCCCTCACTGGCCCACCCACTTGTGTTGAAGCAAAAAGCAAGAATCAATTACTTAAAGGCAAAGGAGTGATATTGCTAAAGCATGTGAGTAATCATTGCTTCTGATTATTGAAGAGGTCAGATTATGAATGAAAGGATAAAATGTTTTAATAGTAGAGCAGTGTCCTGACTATAGGGGCCCGTTCATGGAGCTGGTCATTTCTTGAAATGAGAAGAAACCAACCTGGAAGATGTCTTTTTCAGTAGAGTATGGAATAATCTTACCTGCTCTGGATTGCCATGAGCAGGTGAAAATGAAGGCTCTGATATTGTGTGGTGGTGTCACAGGATGGTGGGGGCGGGGCAGAAGTCTCCTGTTGGTGTTCTGATGCCTGTTCAGCTTTGTCCTCAGGAAGGTTTGGTCATCTTGGTTCTGCCATCCTCTTGCCTTCCTACGGCAGCAGCTGTTCATGGCACTGAAGATGTCCCTTCACTGTCCCAAAACTGGCACTAGAAGTGGCTGGGCAGGGGGGCCAGAGTCATAGGAAGGGTCTTGGAGTCATCAGATCTGGGTTCCAGGCATGGTGTGCCTTTTCTTGGCAGGATTGATCTTGAGCAAGTCAATGAACCTCTGCATCAATTTCCTTATGTGTGAAGTTAGAGTGCTTGGCTGTGCTACCTGATTCCTGAGATTGGTGAAAGAGGGCTTGGTTTACCAAGGCTCTCCATCAGGTGGTTGACCTCTAGGACCAGGGCCCTCTCAGAGGTGCAGCTTCCATGTCAGTTGGTGTTGTAACCATGGAAAAGTCCCTTTCCAATCAAACTTTTAGCACCCCTTTCCCCCCATCTCTGCTCCCTTTGCCACAGGATACCTTGTAAAGTTCCTGCCCCAGTATAGGGATATTTTTACTGTCTTTTTTATTTTTTGAGACAGGGTTGCCCAGGGTGGAGTGCAGTGGCAGGATCACAGCTTACTGCAGCCTTGACCTCCCAGGCTCAGGTCCCATCTGAGCCTCCCGAGTAGCTGGGGCTACAGGTGTGTGCCACCCTGCCAGCTAATTTTTTATATTTTTTTGTAGAGACAAAACTTTTATTTTTTTTTCCCATGTTGCTCATGCTGGTCTCAAACTCCTGGGCTCAAGCAATCCACCCACCTCTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGACCTGTCATTTTTATAGAATGAAATGTGCTTATTTCTAAACATTCTAATCAAATTTTAAAATGTGCAAAGAATGAAGTGAAAAACTGAATTTTTTTTTTTTTTTGATACGGAGTCTCACTCTGTTACCCAGGCTAGAGTGCAGTGGCGCGATCTCCGCTCACTGCAAGCTCTGCCTCCTGGGCTCACACCATTCTCCTGCCTCAGCCTCCTCAGTAGCTGGGACTACAAGTGCCTGCCACCACGCCTGGGTTATTTTTTATATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTCCAGGATGGTCTCGATCTCCAGGATGGTCTCGATCTCCTGACGTCGTGATCCACCCGCCTCGGCCTCCCAAAATGCTGGGATTACAGGTGTGAGCCACTGTGCCCGGCCAAAAGAACAGAAATTATTTTATCCTGAAGTAAGCTGTTTATATTTGGGATTATACTGAACCTATTTGTCCAATAACCTGAGTTTTCAAATAATTTTAGTTCTATAAGTACTATAATTATATAAATATTAATGAATTCAGATTAGCTGAAAGGAAAAAAAGTAGAAGCCTGACTACTTGGTGCTAACTACTAAAGATTTTGGCAGAATCAATGTTGGATTTGGCTTTCCTGTCCCTTCCCCATGCCAGCCCCCCAGAGTGTTCTGCCTTGTGCTGCCTCCCTTCACCTGGAGTGCCACACCCCTCTCTCTGCCAGTTCAGCTCTTCATTCTTCAAGGCCTGACCTTGTCTGACCCTTGTGCCTCTAAACCCGTGGCCCCACCTCTCTTGGTTCCTATGTCAGGTGATGTTTGTGTTTTTGGTTATGCCCATCTCCATAGCCAGACCAAGCACTCTGGAAGCCAGGGTTGGGTGCTTATTTATCTGTTTGCCATGCAGAAAATATCTTGCACAAAATTACCTCTGTTAAGGAATCTGAAGCTGAATTTAGTTTGGCTGAGTCAGGGTTGGGTTTTTTTTAAGGGGCTGTGGGGTGAAATGTTGACTGGAAGCCACCCACAAACACACACCTGCTGGTTAGGAACCCGGCTGTGGGTGGTTCTGAGCTGTTTGGCTTCAGTTGACAGTTTCTGATTGCCCTGAGCACCAGGTCTCATCTTGCATCTCATCCTGGCCTGGAGAACATTCAGTTTCCTTCCAACCCTTCCCACCTTTCCCCCACTCCCTTGGAGGAACTGAAGTTGGGGTTGAGGAGAGCCAGATGGCTGGAGTGGGTATTTGAAGGTCTTTCTGTCACCTGTTCAGTGTGGTCTGCCCCACCCCTGCTGACCAAGACTGACTGAAATGTAAAATAATACAGACCATCTCACACTCAGAAAGCTGGCACATTTTTGAAAGCCCAAGTGTGGGTAAGTGCGTGGAACAACGATAATTCACACTGCTTTATGAGTAGAAATTGTGAGAAATATTGTGCCAGGCAATTTGCAAAATCTTGGAAGGTTGTGTGCACTTAACCACCCAGCAACTACTCCTGGATGCATCCTAGAGAAGTGCCATGTGAACAGAGAATGATTTTAAGACTTCACTGAAGTATTGTTTAGGTAGCAAGATTGGGAAAAGCCTGCATTTCATCAGCAGAAGAATGGATAAATAAATGGGTTGTTTTTGGTCCTTGGAAAGTGAATATGAAAGAGTTACGTCTCAACACAGATAGATGAAAAATTATGCTGAGAAAGTTGGTGAAGCTACATACAAGGTACCCTTAGTGTAAAGTTAAGCATACTGTGTACCTGTGGGCACGTTACTTCAACTTGTTTTTCACTTTTTCTGTAAAATGGGATAGTAGTGGCAATCTCACAGGGTGATTGTGGGTGGGGGGGTGGTCAATGAAGTAATGCATGTAAAATGCTTAGAATAGTGTCTAGCATGTAAGCCTTGTGGACATATAGAAAGTGTTATTGTTTTGCACAGTAATCTATTTTCTGTGGATTCAAATAATATGAAATGAGTATAAAATCATGTATTGGAACGATGTGTGCAAGTCACCATTCTGCCTTCCTAAGGCAGGAGACCTGATGGATTTGGGGAGGGTACATGGGGCCTTCAGTTGTGTTTTCTTTGTTTTTTTCTAAAAATTGATGCAGAGGCATCACAATGTTAAGATTTTTACAGGGTAGTGTGGTGGGTACTTTTTAACTGTTTGCTTAAAGTGTTTCAAAGTAAAAATATTTCTTAAGCATAGTCTCTGACATCTTATGACTTTATAGAAATCCCTGCCAGGTACATGATGTTACTTAGAGTGAGCCACCTAATCTTTCAAGGCTTCCATTTCCTCACCTGCAAAAATTGGGAGTGTCAGAGGCGTTTGAACCAGAGTGACTCCATCTTGAATAGGGAACTGGGTAAAATAAGGCTGAGACCTACTGGGCTGCATTCCCAGGAGGTTAGGCATTCCAAGTCATGGGATGAGATAGGAGGTCAGCACAAGATACAGTCATAAAGACCTTGCCAATAAAACAGCATGTGGTAAAGAAGCCGGTCAAAACCAAGATGGCAATGAAAGTGACCTCTGGTTGTCCTCACTGCTGTAATTATACTGTAATTATAATGCATTAGCATGCTAACAGACACTCCCACCAGTGCCATGACAGTTTACAAACGCCATGGCAGGCCTGGCACGATGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATTATGAGGTCAGGAGATTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAAATACAAAAATTAGCTGGGCATGGTGGCACGTGCCTGTAATCCCAGCTACTTGAGAGGCTGAGGCAGGAGAATCTCTAGATCCCGGGAGTTGGAGGTTGCAGTGAGCCAAGATGGTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAATGCCATGGCAACATCAGGAAGTAACACTATATGGTCTAAAAAGGAGAGGAACCCTCAGTTCTGGTAATTGCTCACACCTTTCCCGGGAAACTTATGAATAATCTACCCCTTGTTTAGCATATAATCAATAAATAACCATAAAAATAGGCAACCAGCAGCCCTTGGGGCTACTCTTCCTATGGAGTAGCCATTCTGTATTTCTTTACTTTCTTAATATTAACTACTTTCACTTTGTGGACTCGCCCGAATTCTTTTCTTGAGCAAGGTCCAAGAACTCTCTCTTGGGGACTGGATCACGACCGCTTTCTGGTAACAGGAGCAATACAAATGGCTATTAGTAAACGAACGCTTAAGTAACTCTAGTACATCTATGATGAAATACCAGGCCACAGTTTTTTTAAAAATGAGGATGTTCTCTATATACTGACGCACAGTCACCAAGACATGCACTTTATAGGAAATTATAAGCTCCTCCTTGCCTAAATCTCCTTAATTTTGCTTAATAAATAACAAGTGAAGCCAGAAGCTGTAAACTCATAATTTTAATGAAGAAATGGGATCCAGAAGATGGAGATGTTTTTCATTCTACTTTATTAGATGAGGAAAAGGAGAGTAAATACTTGTATGCCAGCTACCACACCTTTTAAAGTTAATGTTAACCCTGCTAAGAACAGCAAGGAGATTTTATATCAGCCAGGTTTTAGTTGCCAGAAACCACACCAGTTATTTTAGCAAAGACCTTATAAAGAAGTGTACTATATTTAAGTAGCTAAAAAGGCAAGAAGAAAATGCCAAGGTGTCTTGGAGGTAGCAACTGCTAAGCAGCTGCCACCCCAGGACTGGGGGAGCTAGAATAGAGTCTCCCCATGTTTGACGTTTGTCTGCTAATAGCATTCAAGCTCTCCCCCTCAGTTTGCCTGGATCTGGACAAGCTGATAAGAAAGCCCAGCCACTTCCTCTTTGCGTCAGAGGGGAAGTTCAAACTGTGCAAACCCTGACTGTCAAATGCACTGAGCTCTCATAACCACAACAAAAACCAGAGCCACTTGTTCGTCCTTTCACTGAAGCCCAACAGACTGGCGTGGGTGCCCGCTTTGCTTTCCCTAGAAGGCCTCATGTGAGTAGTAAACTTTTTCATAACCTC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185219-ZNF445:NM_181489:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.474 A=NA C2=0.196
Domain overlap (PFAM):
C1:
PF0135222=KRAB=PD(0.1=0.0)
A:
NA
C2:
PF134651=zf-H2C2_2=WD(100=3.5),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.3),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=3.3),PF134651=zf-H2C2_2=WD(100=3.6),PF0009621=zf-C2H2=WD(100=3.2),PF139121=zf-C2H2_6=WD(100=3.6),PF0009621=zf-C2H2=WD(100=3.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTAAGGGGAATCCAGTTGC
R:
GCCACAGCCATGTTTAAGGGA
Band lengths:
355-1128
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)