HsaINT0187285 @ hg38
Intron Retention
Gene
ENSG00000083838 | ZNF446
Description
zinc finger protein 446 [Source:HGNC Symbol;Acc:HGNC:21036]
Coordinates
chr19:58477179-58477826:+
Coord C1 exon
chr19:58477179-58477560
Coord A exon
chr19:58477561-58477636
Coord C2 exon
chr19:58477637-58477826
Length
76 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
3' ss Seq
GACCTACCTCTTCTCCTCAGATC
3' ss Score
9.81
Exon sequences
Seq C1 exon
GCCCATCTTGACGATTCCAAGACCACCCCCTTGAGCAAGAATGCCATCCCCTCTGGGTCCCCCATGCCTGCCCGTCATGGACCCAGAGACCACCCTTGAGGAGCCTGAGACTGCCCGCCTCCGCTTCCGAGGGTTCTGCTACCAGGAGGTGGCAGGTCCCCGAGAAGCCCTGGCCCGGCTGCGTGAGCTGTGTTGCCAGTGGCTGCAGCCTGAGGCACACTCCAAGGAGCAGATGCTGGAGATGCTGGTGCTGGAGCAGTTCCTGGGCACACTGCCTCCCGAGATCCAGGCCTGGGTGCGCGGTCAGCGGCCAGGCAGTCCTGAGGAGGCCGCTGCCCTAGTCGAAGGACTGCAGCATGACCCTGGGCAACTGTTGGGCTGG
Seq A exon
GTGAGTGTGGCTGGCATCAGCTTCTTGGAGGGATAGACCCTGGCTAGAGCCATTGTGACCTACCTCTTCTCCTCAG
Seq C2 exon
ATCACAGCCCATGTCCTGAAGCAGGAGGTGCTCCCTGCAGCCCAGAAGACAGAGGAACCACTTGGGAGCCCCCACCCCTCAGGGACAGTGGAGTCCCCTGGGGAAGGTCCCCAGGACACCAGAATAGAGGGGTCTGTCCAGCTCAGCTGCAGTGTGAAGGAGGAGCCCAATGTCGATGGACAGGAAGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000083838:ENST00000594369:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.358 A=NA C2=0.855
Domain overlap (PFAM):
C1:
PF0202312=SCAN=WD(100=82.5)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGATGCTGGAGATGCTGGTG
R:
CTTCAGGACATGGGCTGTGAT
Band lengths:
174-250
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains