HsaEX0073710 @ hg38
Exon Skipping
Gene
ENSG00000083838 | ZNF446
Description
zinc finger protein 446 [Source:HGNC Symbol;Acc:HGNC:21036]
Coordinates
chr19:58477179-58478181:+
Coord C1 exon
chr19:58477179-58477560
Coord A exon
chr19:58477637-58477826
Coord C2 exon
chr19:58478087-58478181
Length
190 bp
Sequences
Splice sites
3' ss Seq
GACCTACCTCTTCTCCTCAGATC
3' ss Score
9.81
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
Exon sequences
Seq C1 exon
GCCCATCTTGACGATTCCAAGACCACCCCCTTGAGCAAGAATGCCATCCCCTCTGGGTCCCCCATGCCTGCCCGTCATGGACCCAGAGACCACCCTTGAGGAGCCTGAGACTGCCCGCCTCCGCTTCCGAGGGTTCTGCTACCAGGAGGTGGCAGGTCCCCGAGAAGCCCTGGCCCGGCTGCGTGAGCTGTGTTGCCAGTGGCTGCAGCCTGAGGCACACTCCAAGGAGCAGATGCTGGAGATGCTGGTGCTGGAGCAGTTCCTGGGCACACTGCCTCCCGAGATCCAGGCCTGGGTGCGCGGTCAGCGGCCAGGCAGTCCTGAGGAGGCCGCTGCCCTAGTCGAAGGACTGCAGCATGACCCTGGGCAACTGTTGGGCTGG
Seq A exon
ATCACAGCCCATGTCCTGAAGCAGGAGGTGCTCCCTGCAGCCCAGAAGACAGAGGAACCACTTGGGAGCCCCCACCCCTCAGGGACAGTGGAGTCCCCTGGGGAAGGTCCCCAGGACACCAGAATAGAGGGGTCTGTCCAGCTCAGCTGCAGTGTGAAGGAGGAGCCCAATGTCGATGGACAGGAAGTGG
Seq C2 exon
CACCCTCCAGCCCTCCACTTGCAGCACAGTCCCCTGAGGGGAACCATGGACACCAAGAACCAGCCTCCACATCCTTCCACCCACCCAGGATTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000083838_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.358 A=0.855 C2=1.000
Domain overlap (PFAM):
C1:
PF0202312=SCAN=WD(100=82.5)
A:
NO
C2:
PF0135222=KRAB=PU(3.2=3.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCACACTCCAAGGAGCAGATG
R:
GGATGTGGAGGCTGGTTCTTG
Band lengths:
242-432
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development