HsaINT0187286 @ hg38
Intron Retention
Gene
ENSG00000083838 | ZNF446
Description
zinc finger protein 446 [Source:HGNC Symbol;Acc:HGNC:21036]
Coordinates
chr19:58477637-58478181:+
Coord C1 exon
chr19:58477637-58477826
Coord A exon
chr19:58477827-58478086
Coord C2 exon
chr19:58478087-58478181
Length
260 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
3' ss Seq
CCATCTGCCCCACTTTTCAGCAC
3' ss Score
8.87
Exon sequences
Seq C1 exon
ATCACAGCCCATGTCCTGAAGCAGGAGGTGCTCCCTGCAGCCCAGAAGACAGAGGAACCACTTGGGAGCCCCCACCCCTCAGGGACAGTGGAGTCCCCTGGGGAAGGTCCCCAGGACACCAGAATAGAGGGGTCTGTCCAGCTCAGCTGCAGTGTGAAGGAGGAGCCCAATGTCGATGGACAGGAAGTGG
Seq A exon
GTGAGGTTGGGGTCCCACCAGAGATGAGGGACTCCTGGAGGAAGTGTGGACATTCCTGGCTAGGGTGGGAGTCCCAGGAGAGGTGTGTCAAGGCTGGGACTCCTGAAGTGAATGTGGATGTCCCTGTCTGGGATGGGGACCTGGGAGGCAGGAGCCAAGGGCTGGCTACGTGCCATGTCACACAGCAGAGGAGCTCCTCATCTGCCATGGCTCATGTGGGCAGCCCCTGACACCACCCTTCCATCTGCCCCACTTTTCAG
Seq C2 exon
CACCCTCCAGCCCTCCACTTGCAGCACAGTCCCCTGAGGGGAACCATGGACACCAAGAACCAGCCTCCACATCCTTCCACCCACCCAGGATTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000083838:ENST00000594369:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.855 A=NA C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0135222=KRAB=PU(3.2=3.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCACAGCCCATGTCCTGAAG
R:
TGAATCCTGGGTGGGTGGAAG
Band lengths:
284-544
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains