HsaINT0187287 @ hg38
Intron Retention
Gene
ENSG00000083838 | ZNF446
Description
zinc finger protein 446 [Source:HGNC Symbol;Acc:HGNC:21036]
Coordinates
chr19:58478087-58479727:+
Coord C1 exon
chr19:58478087-58478181
Coord A exon
chr19:58478182-58479642
Coord C2 exon
chr19:58479643-58479727
Length
1461 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
GTGATGGGCCACATCCGCAGGAG
3' ss Score
4.61
Exon sequences
Seq C1 exon
CACCCTCCAGCCCTCCACTTGCAGCACAGTCCCCTGAGGGGAACCATGGACACCAAGAACCAGCCTCCACATCCTTCCACCCACCCAGGATTCAG
Seq A exon
GTGAGCAGCCCCAAGTGGGAAGTATAGGCCCCAGGTGTGAGAAGGGACTGTCCCCATGGCTGCCCTCTGCCTGGTGGTTTTCCAGGCTCCTTGACTAGTGGCTCTTTGCTTCCCAGAAGTGGAGTCTGTAAAAGCTGTACCCCTCCACAGGACCTGGGGCAGAGGGACAGACTGGTGATCTATTATTGAAAAGGATTTGGGGCTGGACATGGTGGCTTACACCTGTAATCCTAGCACTTTGGGAGGCTGAGGTGAGCGGATCACCTGAGGTCAGGAGCTCGAGACCAGCCTGACCAATGTGGTGAAACCCTGTATCTACTAAAGATACAAAAATTAGCCAGAAGTGGTGGCAGGCGCCTGTAATCCCAGCTACTAGGGAGGGTGAGGCAGGACAATTGCTTGAACCCAGGAGGCAGAGGATGCAGTGAGCCGAGATTGTGCCACTGCGCTCCAGCCTGGTCAACAAGAGCAAAATTGTGTGTCAAAAACAAAAAAAAAAAAAAGGATTTGGGCCTCAAGCCATGGAAACCCAGTTTAGAGTGGCTGGAACTAGTGGGCTTGGCTTCCTCACCTCCAGAGAAGTCAGCTGGGAGGTTTGCTGCTCCCAGAGGTCCTGAGCCAGACCTGGGGATTTGAACTTTTGTGTGTAGCTGGGGAGGGGAGAAGATGACCAGCTGTGGCAGGACTCCCCCCACACCTGAGACCAGATGGAGACACTCTCCCTGGGAAATGCCCGAAGTCCCTTCTCTCCTAGGGGTTTCTTCAGAGGCCACCTGTTAGGCCTGGAAGCTCAGCTTGAGGCCTCTTCTACCTGGATCGCTTGGTTCCCAAGTGTGGGTAGCAAGGTCTTTTCCTCTCCCGGCTCCTCTAACAACTCCACTGGGGAGCTTCAGCAGCAACATTGCTGGTTGAGATGTGTTTCGAGGCTAAGAAGTCCTTCCAGGCTCCCTCCACAGCCCCATGGCACAGTCAGAAAGTGAGGCAGGGTGGGTAGGCTGCACTTCCCAGTGTCCTCACCTCCAGCCAGCACCATCTCTAGCTGTGGCTCCTCACAGCTGCCGCCTTCCTGCCCCTGGACTTGCCACAGCTTGTCCCTCAGGATTATTTTTCCCAACCCAGCAAAGCCCCAGATGATGGGACTCAGGCAGCAAGGAGGGCTGACCCCCAATCAGGGAGTTCATTCCTCGATAAAGTCACTCAGGTCCCTGTGATGCTGCCAAACCTGCCCTCTGAGCAGGATGGTGTAGTAGAGGGGGATGAGTGCTGGCAGCAGCACTGGTCAGGTGATCTGAAGGAGAACCTCTGCACTTAACAAACACACACCTTGAGATCATTCTCAGCAGGAGGGGCAGATGAGGCGTAGGTAACCTGCTGACTCTTCCGGGTAATAGGTAAGAATGTGAACCAGACAGGGCAGGGAAGGGGTGGAAAGACGCCTACAGTGATGGGCCACATCCGCAG
Seq C2 exon
GAGGAGTGGGGGCTGCTGGACCGGTCACAGAAGGAACTGTACTGGGATGCGATGCTGGAGAAGTACGGCACAGTGGTCTCCCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000083838:ENST00000594369:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.506
Domain overlap (PFAM):
C1:
PF0135222=KRAB=PU(3.2=3.1)
A:
NA
C2:
PF0135222=KRAB=FE(90.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains