HsaEX0073711 @ hg38
Exon Skipping
Gene
ENSG00000083838 | ZNF446
Description
zinc finger protein 446 [Source:HGNC Symbol;Acc:HGNC:21036]
Coordinates
chr19:58478087-58480019:+
Coord C1 exon
chr19:58478087-58478181
Coord A exon
chr19:58479643-58479727
Coord C2 exon
chr19:58479930-58480019
Length
85 bp
Sequences
Splice sites
3' ss Seq
GTGATGGGCCACATCCGCAGGAG
3' ss Score
4.61
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
Exon sequences
Seq C1 exon
CACCCTCCAGCCCTCCACTTGCAGCACAGTCCCCTGAGGGGAACCATGGACACCAAGAACCAGCCTCCACATCCTTCCACCCACCCAGGATTCAG
Seq A exon
GAGGAGTGGGGGCTGCTGGACCGGTCACAGAAGGAACTGTACTGGGATGCGATGCTGGAGAAGTACGGCACAGTGGTCTCCCTGG
Seq C2 exon
GGTTACCGCCCCACCAGCCAGAGGCACAGGCCCAGTCAGAGCTGGGGATGCTGCTCACGGGGACAGGCGTCTGCAGAAGCCTGCGCTCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000083838_CASSETTE3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.506 C2=0.835
Domain overlap (PFAM):
C1:
PF0135222=KRAB=PU(3.2=3.1)
A:
PF0135222=KRAB=FE(90.3=100)
C2:
PF0135222=KRAB=PD(0.1=0.0)
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCAGCCCTCCACTTGCAG
R:
CTTCTGCAGACGCCTGTCC
Band lengths:
170-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development