HsaINT0187288 @ hg38
Intron Retention
Gene
ENSG00000083838 | ZNF446
Description
zinc finger protein 446 [Source:HGNC Symbol;Acc:HGNC:21036]
Coordinates
chr19:58479643-58480019:+
Coord C1 exon
chr19:58479643-58479727
Coord A exon
chr19:58479728-58479929
Coord C2 exon
chr19:58479930-58480019
Length
202 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
3' ss Seq
TGTGCCCCCCACCCGGGCAGGGT
3' ss Score
7.36
Exon sequences
Seq C1 exon
GAGGAGTGGGGGCTGCTGGACCGGTCACAGAAGGAACTGTACTGGGATGCGATGCTGGAGAAGTACGGCACAGTGGTCTCCCTGG
Seq A exon
GTGAGGACCAGCCAGCCCCACCCCGCCCCTCTCCCTGGGGCCTGCACCCACCCTGCAGCAGGCCTAGCTGGGCAGGGCCTCTGTGCTACCAGCCCTACCCAGCTCTCCCACCTTCCAGAGGAACACCCTGTCACCTACCAGAACCGACCCCACCCCTCCTTCATGCAAACCCCATGCCTAACTGTGCCCCCCACCCGGGCAG
Seq C2 exon
GGTTACCGCCCCACCAGCCAGAGGCACAGGCCCAGTCAGAGCTGGGGATGCTGCTCACGGGGACAGGCGTCTGCAGAAGCCTGCGCTCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000083838:ENST00000594369:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.506 A=NA C2=0.835
Domain overlap (PFAM):
C1:
PF0135222=KRAB=FE(90.3=100)
A:
NO
C2:
PF0135222=KRAB=PD(0.1=0.0)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGAGTGGGGGCTGCTG
R:
CTTCTGCAGACGCCTGTCC
Band lengths:
164-366
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains