HsaINT0188058 @ hg19
Intron Retention
Gene
ENSG00000188295 | ZNF669
Description
zinc finger protein 669 [Source:HGNC Symbol;Acc:25736]
Coordinates
chr1:247263264-247265093:-
Coord C1 exon
chr1:247265033-247265093
Coord A exon
chr1:247264622-247265032
Coord C2 exon
chr1:247263264-247264621
Length
411 bp
Sequences
Splice sites
5' ss Seq
AAGGTAATT
5' ss Score
8.83
3' ss Seq
TGCTTGTCATTTTTTTACAGAAA
3' ss Score
8.74
Exon sequences
Seq C1 exon
GAAGCCAATGGAAAGACCAGAATATTGAAGATCACTTCGAAAAACCTGGGAAAGATATAAG
Seq A exon
GTAATTTGCACTGAGCAGAGGAAATAAAGTCCTCTGAAGGAATCTTAGCATGTCATGAACTTAAAAACAAGCAATCAAAACAAATAAGAGTCACTTGAAATTTATTTATTTTTAGAAAAATTTCACCCAAAATGTAACGTACTTCAATGTAGCAGTCAGTGTTTGCAAAAGAGTTTACTTGAAAATAGTACTACAAAACTGTGTATATGAATATTACTATTTTGGTCATAGCCATGCAGGTGGTAGCTGTGTTTTCAGTAGTAACCCATTTACTTTGAAATAATTCAGTCATGGCAAAAAAAAAAATGCATTTTCCCTGATATTGGTAGCAGTGTAAGTCCAAGACCTATTAATAAGTAGAAAGTTATTAATAAACCAACCAATAATAATGTGCTTGTCATTTTTTTACAG
Seq C2 exon
AAATCATATCGTACAGAGACTGTGTGAAAGTAAAGAAGATGGTCAGTATGGAGAAGTTGTCAGCCAAATTCCAAATCTTGATCTGAACGAGAACATTTCTACTGGATTAAAACCATGTGAATGCAGTATTTGTGGAAAAGTCTTTGTACGTCATTCCCTCCTTAATAGGCATATCCTAGCTCACTCAGGATACAAACCATATGGAGAGAAGCAATATAAATGTGAACAGTGTGGGAAATTCTTCGTTTCTGTTCCAGGTGTTAGAAGACACATGATAATGCACAGTGGAAATCCAGCTTATAAATGTACGATATGTGGGAAAGCTTTTTATTTTCTCAATTCAGTTGAAAGACATCAGAGAACTCACACAGGAGAAAAACCCTATAAATGTAAACAATGTGGTAAAGCATTCACTGTTTCCGGTTCTTGTCTAATACATGAACGAACTCACACTGGAGAGAAACCCTACGAATGTAAGGAATGTGGGAAAACATTCAGATTTTCTTGTTCTTTTAAGACGCATGAAAGGACTCACACTGGAGAAAGACCCTATAAATGTACCAAATGTGATAAAGCCTTCAGCTGTTCCACTTCCCTTCGTTACCATGGAAGCATTCATACTGGAGAGAGACCCTATGAGTGTAAACAATGTGGCAAAGCCTTTAGTCGTTTGAGTTCCCTTTGTAACCATAGAAGTACTCATACCGGAGAGAAACCCTATGAATGTAAACAATGTGATCAAGCCTTCAGTCGCCTCAGTTCCCTTCACCTCCACGAAAGAATTCATACTGGAGAAAAACCCTATGAATGTAAGAAATGCGGTAAAGCCTACACTCGTTCCAGTCACCTTACTCGCCATGAAAGAAGTCATGATATAGAGGCTGGGTGTAGTGACTCAGCCTATAATCCCAGCACTTTGGGAGGCCAAGGCGTGTGGATTGCTTGAGCCCAGGAGTTCATAACCAGCCTGGATTAAAACAATGTGAAACAACCTGGGCAACATGGTGAAACCCTGTCTTTACAAAAAATAAAATAATGCCGGGCACGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGCAGACGCCTGTGGTCCCAGTTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCCGGGAGGCGGAACTTGCAGTGAGCCGAGATCGCACCACTGCACTTCAGCCTGGGTGACAGAGTGAGACTCTGTCTCAAAAAATAAGATAAAATAAAATAAAAAAATAATTAGCTGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188295-ZNF669:NM_024804:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.113 A=NA C2=0.006
Domain overlap (PFAM):
C1:
PF0135222=KRAB=PD(0.1=0.0)
A:
NA
C2:
PF0009621=zf-C2H2=WD(100=7.3),PF134651=zf-H2C2_2=WD(100=7.9),PF134651=zf-H2C2_2=WD(100=8.2),PF134651=zf-H2C2_2=WD(100=7.6),PF134651=zf-H2C2_2=WD(100=8.2),PF134651=zf-H2C2_2=WD(100=8.2),PF134651=zf-H2C2_2=WD(100=7.9),PF134651=zf-H2C2_2=WD(100=8.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGATCACTTCGAAAAACCTGGGA
R:
AGCTTTCCCACATATCGTACAT
Band lengths:
358-769
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)