HsaINT0188274 @ hg19
Intron Retention
Gene
ENSG00000139651 | ZNF740
Description
zinc finger protein 740 [Source:HGNC Symbol;Acc:27465]
Coordinates
chr12:53580175-53584654:+
Coord C1 exon
chr12:53580175-53580293
Coord A exon
chr12:53580294-53581284
Coord C2 exon
chr12:53581285-53584654
Length
991 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
AACCCTCCCTTTCTTCTCAGTGT
3' ss Score
9.88
Exon sequences
Seq C1 exon
GTGAGAAGCCATTTGAATGCGATATATGTGATATGCGTTTCATCCAGAAGTACCACCTGGAACGCCACAAGCGTGTGCACAGTGGTGAAAAGCCTTACCAGTGTGAACGGTGTCATCAG
Seq A exon
GTAAGGCTCATCCCTGCTACAATACCCCACACACACTTTTCCTTCCCCAAGAATCAGGGCCACCCTCCACTCCTGCCTGACAAAAGAGCCACCAGCGTTACTCGCCATAATAGTTAACACATCGGGGTGAAGTGCATCTGTCTGGCCTTATGCAGCTGATCATGGGGAGCAGCAATTAGAACATTGTAATAATAATAATAATAGCATTCCATATCACTTACTCTATGCCAGGCACTGTGAGAGCATACTTTACATAGATGATTTTATTTAATCCTCACATTGACTCCCTAAGGTAGCTGTATTGTCCTTATTTCACGTATGGGAAAATTGAGATTCAGAGAAGTTAAGTTTCCCAGGGACACCGCAGATCACGAACAGAGCTGGGATTCAGTCCAACTTCAGAGCTAATGCACTTTGGAGGAAGAGATACAATCTTTGCCCTGGGGGTCAGTATCTGATCTGATGAGAATGTAAGAGCTGGGGCCAAAACAAGACAAGAACAAGAGATGAGAAATGATAATAGCTAACACTTCCTGGATGCATTGCTAGGTCCCAAGCTTTGCTCTGCACTCTTACACTGAATCTTCAGACGCTAGAATAAAAGCTCCATGAGGGCAGAGACTTTGTTCCTCTGGTTCTCTACTCTGTATCTGCCTTGAGATAGATACTCAATAAATCTTTGATGAATAAAGCAGCTGTGCTGTGAGTAGGTACTTTTAGCCTCGCTTTGCAGTTTTGCAGATGAGTATGCAGATTCTGGGCTGTTAGGTAACTTGCCCAAGGTCACACAGCTGCTGAGTGATAGAGCCAAGATTCAGCCCCAGGCGGTCTGGCCTGAGAGCTTGGATTCTCCACCACCGTGTGCTCCTGCTGTCTGTGCACGTGCTGAGGGGATGGAGAATGTGGTATCTGCCTCCTGTGAGAGGAATGAGTTAGCCAACAGGTAGCTGCGTTTGTCTGCTCAGGCACTTAACCCTCCCTTTCTTCTCAG
Seq C2 exon
TGTTTTTCTCGGACAGATCGATTACTCAGACACAAACGGATGTGCCAAGGGTGCCAGTCCAAGACTTCCGACGGGCAGTTTTCTCTATAGGCGCAAGGGGCCCCGGGTGGTGGGAGTGATCAGAAGAACCTGCCGAAGAGCACACCCCCTCTGGTCTGATGGTCCCACCACCGCCCCATGTGAACCTGTCCCACTCCTGGAGGAGTGGACCCAGGAGACCAGAAGAGTGCATCAGGGGACAGTGGCCCCAGAACCTCAGCTCTGTAAATAATCTGAGACTATGAGTATCTCGGGGAAGTTCTTACAGCATTCCTGGGTAGGGGAGCTAGTCCCTGGACCCTTGGCTGAGGTCATAGGTGGGGACTCAAGGTACAGGACCAAGACTGAAGTGTGGCTCCCACAACCTTGGACTCCAGCTGGCAGCTGAAATGGAAAAGATTGGGGAAGGGGATTTGTTTGTTCTGTTCTTGTTTTTGTTTATCCAAAAGCAACTTCAGCGGGTAAACTGTGGATACAGGTAATCCAGAGGCATAAGAGTCCTGGTCCAAAGTAGGGACTATAGCTGGTCCAGCTCTCCCCAAAAATTGGGTTTTTAGTTGCAGTAGCTCCTCAGTGTTTCACAATCCTGCACTTCGCCTCCTTTTTGAGGAAGAATAAGGTCAGGAATGGCAGCTGAGCTTACTTTGGCTTCCTTATACACTGTAGGGACAAAAGGAAAAACGGGGTGGAGCAGACAAGGGCTGGATCCAAAAAGTGGATGGCACCTCTTCCTTCCTCAAGGGAAAAGGAAGAGTTGTGCCAGTGGGTGTTGTCATGGCCCATGTCACATTGGCACCTGATGGCATCAGCTCAAATGCCTTTAGGAGGAAACTTGGGTGAGAGTGGCCCATGAAGCCCTTTTCTTCTTTTTTTGGGGAGTCGGTCTTGGAGATGGTATGTGGCTACCTCGCTGCCATTGACTCCTAAAGTGAGACAGATGTGTTGAGCAAGGAGTCATGGAAGTCAAAGTGGGTTCTCTCTCCTTGTGCCCTCTTAGGAACAACCCAAGACTGGTCCCAAGTTGGCTAACAGCTGCTCAAGAAACAAAGGAATCTGGGGTCTTCTGACATGCCTGTTGAGCAGTAGGAGCTGTTCTCCCTCCCCAAGTCCTATCACTGTATTCAGGTAGAGGAGGTAGGGAGGGGTCTGTCCTTTGGTCCCAAAAAACAAGATCTCGGCTTGCTTCCTGATGGCCATCCCTACCCAACAGAGTGTGGGGGATGGGGGTGGGGGTGCTGCAGAGAAAAGACTAAAGAAGAAACCTAATGTAGGTTCCATTCTTAACCATATTCTTTGCTCCTCTCTGCTCCAATACCACCACCTTGTCCACTCCCAAAAAAGTAATCGGGTGTGTGTGTGTGTGTGAGAGAGAGTGTGTGTGAGATATGAATGCATGTATTTGTATGCTTGCAGGAGATGGCATATTATTGAGCCAAACCCTTCTCTGGCCCTCACCTTCAGGGAGGATGAGTGGAAAATAGCCTCCTCTTGCCCAAACATGAAGGGTGCTTGAGGTCTCAGCAGGAGCTGAAGAACACAATTTGGGGAACAGAAGGGCTTTTGTTTTGGAGGGTTTTTTTTTTTAAGATGAATTCAACAGCCTGGTGGTTAGGATGTTTCTAACCCAAGCCAGGGCTTGTGAACATGAATTTTCTAAGGTGAAATAAACCTTTTCTTTCTGCTAAAGAAAGAATCCTTATGGGAAGTTTTGGGGTTTGGTTGACCCCCACTGTAACCTGACCTGACCTGTGGCGGGTACGGGAACTGTCTTAGTAATCATGGAGACTGGCTGAACCTGAGTGCCAAGCTGTCAGTAGGGTCTGAGATGGGAAACTCCTGAAAGTATGATTTCATTTCCCAGAAAATGTAAAGAATGGATACCAGCAATGATTCCTGGCTGTTACCTATTCTGGAGGGGTGGGGTTGGGGAGGGGGTTGTCCATACCTCTGTGGTATGAGTATTTCAGGGAAAAAGAAAGCAGGCATGGCACCCATTCGATTTTCCCTGACAGCATCTGAGATCCTTTTGGGGAGACGCTGAGGAGTGTTTGCTGCCATGTACTCTTACAGCTCTATGCTGACACTCCCATTTGATGTGGTCCAGAACTTAGACCTCAGTCCTTGGATCAGCCCTGTGGTCCCTGCAAGCAGGGGCATCTTTCTGCATGTGAGCCAGCCCCCTTCCTGTTCAAGGGTTCTGCTGGATCTGGGCTTTTCCTGTCCTTCACTTCTGGGATGATTCACCCCACATCTTCCAGTACCCTGTAAACCATTTTAAAATATTTAGAAAACTATCCTCCCAAAAATGCTTTTGAAAATGAGAGCCCTCTGTCCCTGCCACTTACAGCTAGTCTCTTTGGGATAGGGGTGTATGTGGAGAGATTCATGTAAGTCTCACATGAGTGACCTGTGCCCCTATGTGTACTAATGTGTGTACTGGGTCAGAAGGTGCCCTGGGTTCCCACAGACCTTGGTTTCCTGCCTGGGTGGGTGGGAGGGAGGGAACTTCAGAGAGTATGTGCGAACAGCCATAGCAGAGCCACCCCTGCCAAGGACCCAGTGAGGGAAACTCAGGAGCAGGTGGTTGGTTCAGTTCCCGCGCTGATGTCTGGGGCAGTGCATGTGTGAGAAGAGAGGCGCAAAGCAGTGAAAGGAGTGATTTGGCATCCAGAGGGCCCGGGAGCCCCACGGATACCCCAGGGAAGCCACTGACTCACACCGCTGCAGAGGCTCCTGGGCCCAATGCCCGACCCCTGCTGGCCAGCATGGGGCCTAGCACTGGAAGATGCCTCAGGTGTGTTTGGAGTGGGGGAAACGGAAGTAGGGCACGCTCTCAGAGACCAGGATAGAGAGTCAGGGAACCTGGGAAAGAGTAGTGCCAGTTCCGGGTAGGCTGCTGCACCAGGCCCTACCAGCTCAGGCTATAAACAGTCTGCTTTGCCCCAAGTCTTTTCCGTCCACCCCCAACAGCCTTGTCATCACTTAGCTACTGATCACGCCCATGGCTTGACATTGGAGGGTTACATTAGTGGAGTCCGCCACAGCTTCGAACCCTCTCCCCAGATGCCCTTTGCCTCTGCTGTGGCCCTGGGGTTTTATCAACTGTCCCCTTCCTATCCTCCTCTCCACCCTGTTTTTTGTTTTTTTTTTTTTTAAATAATATTTTGCTATGGGGGAGGGGAATATCAAATGGACAAGATCACTTTTAAATGGTAGTTTTTATAAGATGTTATAAACTTGTATCTTTTTACCATTAAAGTGCAGTGTATGTTCCTTCGTGATATATTTAGGATATTTAAATAAAAGGAAAATGGGGCTTTTCTACATACTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000139651-ZNF740:NM_001004304:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127602=Zn_Tnp_IS1595=PD(26.7=30.0),PF134651=zf-H2C2_2=PD(57.7=37.5),PF134651=zf-H2C2_2=PU(80.8=52.5)
A:
NA
C2:
PF134651=zf-H2C2_2=PD(11.5=10.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGCCTTACCAGTGTGAACGG
R:
CCCCTACCCAGGAATGCTGTA
Band lengths:
353-1344
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)