HsaINT1000288 @ hg38
Intron Retention
Gene
ENSG00000143322 | ABL2
Description
ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:77]
Coordinates
chr1:179131311-179133374:-
Coord C1 exon
chr1:179133312-179133374
Coord A exon
chr1:179131482-179133311
Coord C2 exon
chr1:179131311-179131481
Length
1830 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
3' ss Seq
TCCCTTCTTATGTCTTTCAGAAG
3' ss Score
9.61
Exon sequences
Seq C1 exon
ATCACTTTGCCAGCTGTGTGGAGGATGGATTTGAGGGAGACAAGACTGGAGGCAGTAGTCCAG
Seq A exon
GTGAGAGATGTTGAGATGTTGCAGATTTGAACTAAGGCATTGGCAGTAGAGATGGAGAACAGGGAATGGATTTGAAAATAAATGGAACCACAAATTCAAGGGTTTTTCCTTTCATATATGATAAAACTATTTTTATATTAAAAATAAGTTGGCCTGGCTGGGTGTGGTGGCTCACGTTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCAGATCACAAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACTTCGTCTCTACTGAAAATACAAAATTTAGCTGGGCTTGGTGGCGTGCACCTGTAATCCCACCTACTCGGGAGGCTGAGGCAGTAGAATTGCTTGAACCTAGGACGTGAAGGTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAACAAGACTCCATCTCGGTGGTGGGAGAGGGGTGCGGACGGGGAATAAGTCAGCCGGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAACCTGGCCAACATGGTAAAATCCTGTCTCTACTAAAAATACAGAAAAATTAGCTGGGTATGGTGGCAGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACGCTTGAACTCGGGAGGCAGAGGTTTCAGTAAGCCGAGATCACGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCCATCTCAAAATAATAATGATAATAATAATAATAATCATAATAATCATAAGTGGAGGAAGAGAGACATAAAAGTGTTGTTATATGACATAGACATTTGGATAGTTTGCCTTTGTAGACAGGCACTAAAAATAGTCTGATCAAGAAAATTGATACTGGAAAAACTGTTTTTTGTATAATCGATCTGGGCTGTGAGAAGCAGGTGATCTTTAAGATGGTATAGGGATCACCTGTGCTATGTACTATGAATAAATTTAGAAACTGTAAAGGCTTAAGGAAAAAACAGGTCGTAAAAGGCTTGGACCACTTTGAGTAGAAACTCAATAAATGCCCGATGATAGTAATGTTTTCTAGGCTCTTCAATTAAGTTATTGATATTTACAAAAAATCACTGCTCAGGAAAACAAAATAGAGTTTAAAAGTCATTCAGGCCGGGTGCGGCCACATTTCTTTTGTTTTTTTAAAACGAAAAAAAGATTATTTTTTGCCATGTTGGCCAAAAAAAGATATTTTTCTAAAAGCACTTTTTAAATAATTTTTTCTATACTTAAATAGAGGGCCTGGATTTATACAGTATTACCTAATTCTGAAAAATAATCCCTGTTGTCTTTTCTACAGTTTGTTTTCTGTGGAGAGAGAAAGGAATAAGGGTAGTTTGAGTGGACTTGTAAGAAACTTACAATCATTTCTTCCTTAAAACTACAACCACTACTACAACAAAATATCCTCTATGTTTTATAAAGCTAGTAACCATTTCTCTTTGAGATTCTTTTTTCCATTTTGAGAAAACTGCGTTTCCTATTAGTTTATGTCTGATTTTGGTGAGTGCATATAAATCACGGCTAAACTCTCATTTTGTGGTCTTTTCTCTGACTACCTTGTTTTACATTTTCAACAAGTAAATTGCTTCCTCATGCTTAGGAGACACAGTGCCTATTTGCTAATTCTTCATAACACTTTATACTGTACAGTTCTTTCCTACTCTGGAGCCAGCAGCTGAAATACTGTGTATATAATGAATTCAAACAAATGTTTCGCTGTTGAACTCACCGTGAATTCCCTTCCCTTCTTATGTCTTTCAG
Seq C2 exon
AAGCTTTGCATCGTCCCTATGGTTGTGATGTTGAACCCCAGGCACTAAATGAGGCTATCAGGTGGAGCTCCAAGGAGAACTTGCTCGGAGCCACTGAGAGTGACCCTAATCTCTTCGTTGCACTTTATGATTTTGTAGCAAGTGGTGATAACACACTCAGCATCACTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143322:ENST00000502732:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.500 A=NA C2=0.109
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0001823=SH3_1=PU(38.3=31.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCACTTTGCCAGCTGTGTGG
R:
AGTGATGCTGAGTGTGTTATCACC
Band lengths:
230-2060
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains