HsaINT1008230 @ hg38
Intron Retention
Gene
ENSG00000145244 | CORIN
Description
corin, serine peptidase [Source:HGNC Symbol;Acc:HGNC:19012]
Coordinates
chr4:47600214-47603668:-
Coord C1 exon
chr4:47603397-47603668
Coord A exon
chr4:47600348-47603396
Coord C2 exon
chr4:47600214-47600347
Length
3049 bp
Sequences
Splice sites
5' ss Seq
AAAGTAAGC
5' ss Score
7.31
3' ss Seq
CTTATTTTTTAAAAATTCAGTGC
3' ss Score
4.32
Exon sequences
Seq C1 exon
GAGAGAGAATGCTGCAGTTTGGAAAGTGGTGCTTGGCATCAACAATCTAGACCATCCATCAGTGTTCATGCAGACACGCTTTGTGAAGACCATCATCCTGCATCCCCGCTACAGTCGAGCAGTGGTGGACTATGACATCAGCATCGTTGAGCTGAGTGAAGACATCAGTGAGACTGGCTACGTCCGGCCTGTCTGCTTGCCCAACCCGGAGCAGTGGCTAGAGCCTGACACGTACTGCTATATCACAGGCTGGGGCCACATGGGCAATAAAA
Seq A exon
GTAAGCCAGTGTATTAGTCCATTCTCATGCTGCTATAAGCACATACCTGAGAGTGGGTAATTTATAAAGGAAAGAAGTTTAATTGATTCACAGTTCTGCAGGGATGGGGAGGCCTCAGGAAACCTACAATCATGGCGGAAGGGGAAGCAAACATGTCCTTCTTCACATGGCAGCAGCAAGGAGAAGTACTGAGCAAAAGGGGGAAAAGCCCCTTATAAAACCATCAGACCTCGTGAGAACTCACTATCAAGAGGGTAACTGCCCCCCATGTTTCAATTACCTCCCACCAGATCCCTCCCATTACACGTGGAGATTATGGGAACTACAATTCAAGATGAGATTTGGGTGGGAACACAGCCAAACCATATCAGCCAGGATCTTCAGGAGCCTGAGAAACATTGTGTTCCTCAGTTGGGAGGCTGAGGTGGGAGGATTTCTTGAGCCTGGAAGGTGGAGGCTGCAGTGAGCCAAGATCTCACCACTGCCTGGGTAACAGAATGAGACCCAGTACCCAGACCCAAAAGCTAGGTAGCTTTTGGCCGTAATTTCCCATTTTCTCTTACAAAAATATAGCCACAAATGGTAAATACTTAGCGATGTGTCACACTTCATCTGCTGTGCAAATCATAGACATTAATAATGAACCATGGCATTTAAAATGGCCAAGCTCAGATGCAATCTCAAAAATCCCTCTCCACACTTCAGAATCTCTCTCTGGGAGCTTACTATTAATGTTTTGGAGCTTCCTTGTGGCAGGAGGAGACCTGTCACTGAACTGTGCTTTGGACTCTCTCTATCTGCCTGCAGATAGCCCAATGATAGAGACAGTCACTGGGAATCTCTGCAGTCAAGCTGCATGGTCATATTTCCAATTCTATGTTGTGATTTGGTCTTATCAACATCTGTAGTACAAACTATAAATCCTTCAAGAAAGTATATTGATTTGCTATTTGACTATTTAAATTGATTAAAATAGTTTGGCTCTGTAGATGACTTAACATATAAAACACATAGAAATTTAAAATGTGTACTCTGTATTTACTCTAAACCCCTATAATGGACTCTCTCATTCAGTTTGACCTACTTTAGAAATAATAATTGTTTGTTTGTTTATTTGTTTGTTTTTGAGACGGAGTCTCACTCTGTCACCCAGGCTGGAATGCAGTGGCACAATCTCGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGACATGTGCCATGACGCCTGGCTAATTTTGTTTTTTGTATTTTTAGTGAGACGGGGTTTCACCATGTTGGCCAAGCTAGTTTCAAACTCCTGACCTCAGGTGATCCACCCACCTGAAACTTAAAAAAAAAAAACTGTAAGTGCTGCCTACTCTGTCCATATCAAGTATAATGCCATGGCTTTCAAGAATAATAATGTATATTGGCATTCTGTTATTGGCCTTAGAAATTGTATATTTGAAGGAATTTTTTCTTAAAATTTAGTCAGATAAGGTTTGACTTACATTGAGTTTCTTTTCTATTTCATCAATTACAGAACAGAAAGGAAATTCAATAGGCAGAAGTCAATGACTTTTTCAAAAAAACTCACATGTAACAATTTTGAAGGCAATGTTAGACATGCTGTCACCACTCCTATGCATCTGTTTTTTTTCAAAGCTATGATTAATTCTGTAATTTAAGAGCAGACTATGCTTGATATTGTTTCTGCTTATATTCCTCCTACAATATCCATATTGAACTCAGAGCAATAGTGCAACATAACGCACACTCCACACATGTAGTATAGCATGAATTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAACATGGTGGAACTCTGTCTCTACAAAAAAAAAATTAGCTTGGCATGGGGGTGTGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATTTCTTGAGCCTTGAAGGTGGAGGCTGCAGTGAGCCAAGGATTTCTTGAGCCAAGGTGGAGGCTGCAGTAAGCAAGTGACCACTGCCTGGGTGACAGAATGAGACCCTGTCTCAAAAAAAAAAAAAAGATCTGCTGAATTCAGTCAGAAAGACCTGACTGATCTGACTGTATAACTTTCAAGCTTACTATAAAATGGAAAAAAATAGCAACTACCTAACTCACAGGAGTATTGTAAAGATTAAAGGCAATGAGACCCACTAGTGCCCAATAAATGTTAGCTATTGTTCTTATTCTTTTGACAACCTGTGAAACATCCACTGTCTGCATCACATTGATTTTCCTAAAAATGGCTCTTTCTTCCAATAAGGTACCCAGTAGTGCTTCACCATCACTGTTTAAAAGAAGAACAGTGTGTATAATTTTGCAGAATGGCTAAACAGTGAAAGATTCATGCTGTCTTGCTTCAAGAAATCCATTGTCATTCTTCAAGAACTTTTAAGCAAGATGGAATTCACATATTCTCTCTGTCAATACCAAGGGATGGCTTTGTGCTTTTCGATATCTCTCTGTCATATCCTCTAGGATTAGAGGTTCTTACATCAAGTAATGGCTGCTGGGGCACATATTGAGGCATATTCTTTTCATCAAGAATAGGACAACCCTTCCCTGTTAGATTAAACAGGTTTTCTCTACTTTAGCAGAGCAGGACTATCATGCTGAGTTGACGCCGAGCTGGCAGCCTCCTATCTGGCAGCCAGCAGAGCTCTGGCTTGATTTTTTTCTTTTCTTTGTAGTAGCTATTGTTTTGGTTGTAGCATATGGTAAGGATGAACCAACTTACTTAACCAGTCTAGGCCTTGGTTTACCCATTAATAAAATAAAGGAGTTTCACCGGATAATTGCTATGAATGCTTCTAACTAGAAAATTCTGATTCCAAACCAGCCATGTCTTTAAAATGGCATTTCAAGTAAAGAATATGCCTCTCTTGGTATAAAAATATTTATATTATATTTGCATTTCATATTTGGCTAGCCTCACTAGCCTCACTTTTGAGTCATTTTATCATCATATATATATTCTTATTTTTTAAAAATTCAG
Seq C2 exon
TGCCATTTAAGCTGCAAGAGGGAGAGGTCCGCATTATTTCTCTGGAACATTGTCAGTCCTACTTTGACATGAAGACCATCACCACTCGGATGATATGTGCTGGCTATGAGTCTGGCACAGTTGATTCATGCATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145244:ENST00000273857:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(39.7=100)
A:
NA
C2:
PF0008921=Trypsin=FE(19.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains