HsaINT1010874 @ hg38
Intron Retention
Gene
ENSG00000140995 | DEF8
Description
differentially expressed in FDCP 8 homolog [Source:HGNC Symbol;Acc:HGNC:25969]
Coordinates
chr16:89949417-89954376:+
Coord C1 exon
chr16:89949417-89949638
Coord A exon
chr16:89949639-89954242
Coord C2 exon
chr16:89954243-89954376
Length
4604 bp
Sequences
Splice sites
5' ss Seq
CAGGTCCGT
5' ss Score
6.47
3' ss Seq
TGGCCCTGCCTGGCCCTCAGGTG
3' ss Score
8.44
Exon sequences
Seq C1 exon
CAGGTGCCGAACCCACGGCCAGGCTTCCGTGGCCAGCAGCCCTAGAGGAATGGCCATCCTGTCCCTGCGAGCCCCTGGGCCCTGGCAGGCGATGCAGGTATGGGCAGACAGGACGCTGTTGACTCCGCACACCGGGGTGACTTCTCAGGTTCTCGGGGTGGCAGCTGCAGTGATGACACCGCTTCCTGGTGGTCACGCCGCGGGCAGGACGCGGGAGGCCAG
Seq A exon
GTCCGTGCATCCCGCGTGTCCTGAGCTTCGGCCCAGGGTCCCTCCGTGCCCCGGAACCCCGCCGGCTTTCTTCGGCTTCCTTTCATTGCTAAGTTGTGGGGTCCTCCCCGATGAGAGCAGTGGGCTCTAGAGGAGGGGCAGGGGGTGGCCAGACCTCTTGCTTTCACTCTTCCACTTCCTGCCCGCTCCTTTCTGAGGCCAAGTCCCACATCTGGGTGCAGAACTGGTGGGGTGAGCCTGGTGAGAGGGGCAGGCTGGCGTTCTGCTCAGAGTCGGCCACTGTGGCCGGCATCCCCAGGTCTGTGTGAGCAGAAGCTAAGGCTGCGAGGCCAGCGGCCTCCCCTCATTCATCCCCTGCCCGTGCGCCAGGCCTGGGGCTGGCACTGACTGTCAGTAAATAGGCAAATAAAAGATGCCTTTTTTCACAGCCCGGAGGAGAGCTGGTAGCCTAGAGTACAGCTGCTGGGCAGAACGGAGGTGTCCCTGCCAGCGTGCCTTCCTTGACGCTCCTCTGGCCATGTTTTAAACACCAGGAGGTTTCCAGCGGCTTCCCCAGGCGTAGCTCCTGCACCTTTTTCCTGGGCTGGTCACCATATGTGATGACAGTGCCAGTCTGTTCTGAGCAGCTCTGGGCTCCTGGCTTCACTGACATCATAAACAAGTCCTTAGCCCTTCCATCCACCCCAGAAAGTAGGTGTTCCCCCTGATTTATAGGCAAGACAATGGAGAACCAGAGTCTAAATCAGGGCTGATTTTTTTTTTTTTTTTGAGATGGAGTTTTGCTGTGTTGCCTAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTCCACCTCCCGTGTTCAAGTGATTCTCCTGCCTCAGCTTCCCAAGTAGCTGGATTACAGGCATGCACCACCATGCCCAGCTAATTTGTTTGTGTTTTTAGTACAGACGGGGTTTCACCATGTTGGTCAGGCTGGTTTGAACTCTTGACCTCAAATGATCCACCCGCCTCAGCCTCCCAAAGTGAGCCACCACACACCGGCCATGATTCTTAAAAATAACAGTAATAGGCCAGGCATGGTAGCTCACACCTATAATCCCAGCAATTTGGGAGGCAGAGGCAGGAGGGTTGCTTGAAGCCAGGAGTTTGAGACCAGCCTGGGCATCAGAGTGAGACTCCGTCTCTACAAAAAGTTAAAAAAAATTAGCTGAGTGTGGTGGCACACACTGGAGTTCCAGCTACTTGGGAGGCTAATATGGGAGGACCCCTTCAGCCCAGGAGTTTGAGGCTGCAGTGAGCTGTGATCGCACCACTGCACTCCAGCTCGGGTGACAGAGCAACACCCTGTCTCAAAAAAAAGTAATAATGATAAATTATAATCAATATTTATTGGGTGCTTACTATGTGCCGGCCAGTGTTCTCTGAACTTAGTATTAACTACTTTAATCTTGACAATAACCCTGTATGGTACTATTGTAATCCCCATTTGAGACATGGGAGAATGGAGGCAGAGAAACGTTTATCCACTTACCCAAGGTCACACAGCTAGGAGCTAGCAGAGTTGGGATTCAAGCTGGACGTGTCTGTCTTGTTACCATGAAACTATTGGGATCATCAGTCAGAATCTTTTCTTTTTTTTTTTTCTGAGATGGAGTCTCACTCTGTCACCCAAGCTGGAGTGCAGTGGCTCAATCTCGGCTCACCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGATGCCCACCACCACGCCCGGCTAATTTTTGTATTTTTGGTAGAGACGGGGTTTCACCAGGTTGGCCAGGCTGGTCTCGAACTGCTCACCTCAGGTGATCAGCCCACTTCTGCTTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGAGCTGGGTCTTTCAGTCAGAATCTACTTTGGCCGCAAGAGACAAAAACCTCCCCTATAACACTGGTGGGAATATCGTATTTCTCTCACTTGAATGAAGTCTGGCTGTGAGCAGCTTAGGGCTCAGGTGCAGTCCCCTGCAATCACGTCACTCTCCCCAGTGTGGCTATTCCAGCTGCAGCCTTTACATCTGCATTCCAGGCAGCAGGAGGCAGGGATGGCTGAAGAGGGGCAGCCCCTACCTTTAAGGACAATTCTCAGAAGTCTTTTCTTTTTTCTCATATGTATGTATACACACACACACATATATATGTATATACACACACATACATATTTATGTAAAAAAGATTTTTTTTTTTTTTGATATGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCGTTCTCGGCTCACTGCAAGCTCCGCTTCCTGGGTTCACGCTATTCTGCTGCCTCAGCCTCCCGAGTAGCTGGGGCTACAGGCGCCTGCCACCACACCTGGCTAATTTTTTGTATTTCTAGTAGAGACAGGGTTTCAATGTGTTAGCCAGGATGGTTTCGATCTCCTGACCTGGTGATCCGCCCGCCTCGGCCTCCCAATGTGCTGGGATTACAGGCGTGAGCCACGGCGCCCAGCCCATATTTGTATAAAATTTAATAGAGATAGGGCCTCATTGCATTGGGCCTGGCCGGATGCCGTCCTCCTGCCTTGGCCTTCCAGAGTGCTGGGATTATAGGTGTGAGCTACCACGCCCGGCCCATTACTGTTGTTTTCAGATAGCCCTGATTTAGTCTCTGGTTCTCCCTTTTCTTGCCTATAAATCAGGGAGAACACGTACTTCCTGGGGTGGATGGAAGGGCTAAGCACTTGGGTATGTCAGTGAAGCCAGGAGCCCAGAGCTGCTCAGATCTGCCTGATCTTCTCAAGCCGAGGGGGTCAGAACAGTCACTTTACCAGGTCTAGCTGCTGGGGAGGCTGGGAAATTATGTGACAAACAAAAATGAGGCTCCTCATTCAGGAAGAAGGAGGAGTGATGTTGGGATGGCCTGATTTCTCCTGTGTCCTGGGTGCTCCCTGGGAGACTGGGGAGGTGCTGGCATCGGGTGGCCGCCTCTGACTCTGTGACCCACCCACAGTCATCAGGTAATAAGAGAAGGAGGTGGGACTGGGGCCCACTCACGTTCCCTGTGTCTTCCCCGTGCCTCCCTGTTGGGGTCCACGGGCAGCCTGTCCATGGGTGCTTTGTCCTTTCAGGCTGGCGTGCAGGTGCCCAACCCACACTCCTGCCCCACAGGCACAACAGGCAGGACAGGCCCCATAGGTGGTGTGGAGTCTTGCCCAGTTGCAGGGCAGCCATGTGGGGTTGGGGTGGCCTCCTTATCCCACTGCCAGTGAGGCAATTAGTTCAAATCCCAGTTCTTCCAGGCCACAGTGTGACCCTGAGCAGGGCCGTCCCCTCTGGGCTCAGCTCTCTTTCTTTTGGGAGAAGAGACAGAGGATAAATCATAGGATTGATTATTATAATTGTGAATTATTTCAGACTGTAGCAGGTGTAGTGAAAGCATAACTAACACTGTAGCAGGTGTAGTGAAAGCATAACTAACACTGTTGCAGTTACTGAACAACTTTAAAAAGACATCTCCGACTTTCTATAACATCAACAGACCTTACAGCGAGCTTACTTTGTGCTCAGTCTCTGTTAACTCATTTCACCCTCACAATGGCCCATTACGGATGGGGAAATGGAGGCAGAGAGGCTAAGGAATGTGGCCCAGGAAGTTAAGTGGGAGGGCTGGATGCCAACTGCCTCTACTCCCACCCCAACCAAAGTCCCTTCCTCCCTGCCAGGAGCCATCAGCCCTGTGTGTTCTGCAGTGTTCTGAGCCTCCGGGTGGGGAAAGAGCAATTCTTGATCCTGAGCTTCTGCCACGTGGAGAACTAGGCCCTTCCGGCCTGTTTCCTGGGTTCCTGAGGCACAGAGCCGTGGGCCTGGTTCAGGTCGTGTTGCTCATCACAGGATCAGAACCCAGGCCAGAGAGCCTGGATGCATTTGTAGGGGGCTTCTCTGTGTGCTGGCAGGGAATCCTCCCAAGATCCCCTGCTCCTGGGCATGGGGAAGGTGGGCCCTGCTCACTCACCTGTGGCAGAGCAGGAATGGGCCCTGGAACTGTCCCCAAGTGTCCAACCCTAAGTCCTGAGACAGGGGCTGTGGTTTCAGGGTGCTCTGACAAGAAAGCACCTTTGCTTGGGGCCCAGGAAGGAGGAACCCATTTCTGAGAGGTGTGTCTCACATAGCAGGTGGATAGCAAGCTAGAGCGGGGCTGAGTGAGTATCTGGGGCTGAGGCCCAGAGAGGATCCCATAGGTAGCTCTAGGGCTGGAGCTCTGCAACATTGGGCAAGAGGACCCTGTGCTGGGAGGCAGGGAGCTTGGGCCCCTCAGATGGGCCACGTGCCCTCGTGGGACCCTCATTGTCACCGTGAGCTCTTTCCAAGGGGACGCCACCAGTGGGGGCCTGGGCAGGAGGCAGCTGAGGTGTTTCAGGAAAAGGCTGAAGATCAAGGCTGTGGTGTGAGGACTACCCACTTTAGGGAAGTGAAAGAGGCCAGCCTCACCCCAGACACCCCAGTGTGGTTGGGGAAAGGGGGTGGTCCGTGGTGAGCCTGGTACCTGGGGACTCATCCTGGCCCTGCCTGGCCCTCAG
Seq C2 exon
GTGGGATGCTATGGAATATGATGAGAAGCTGGCCCGTTTCCGGCAGGCCCACCTCAACCCCTTCAACAAGCAGTCTGGGCCGAGACAGCATGAGCAGGGCCCTGGGGAGGAGGTCCCGGACGTCACTCCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140995:ENST00000268676:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.657 A=NA C2=0.748
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains