HsaINT1011204 @ hg38
Intron Retention
Gene
ENSG00000144355 | DLX1
Description
distal-less homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2914]
Coordinates
chr2:172086654-172089677:+
Coord C1 exon
chr2:172086654-172086853
Coord A exon
chr2:172086854-172088002
Coord C2 exon
chr2:172088003-172089677
Length
1149 bp
Sequences
Splice sites
5' ss Seq
CAGGTACCT
5' ss Score
8.16
3' ss Seq
GTTGTTGTCCGCTCTTGCAGGTC
3' ss Score
10.46
Exon sequences
Seq C1 exon
GGGCGGACTCGGAGAAGAGCACGGTGGTGGAAGGCGGTGAAGTGCGCTTCAATGGCAAGGGAAAAAAGATCCGTAAACCCAGGACGATTTATTCCAGTTTGCAGTTGCAGGCTTTGAACCGGAGGTTCCAGCAAACTCAGTACCTAGCTCTGCCGGAGAGGGCGGAGCTCGCGGCCTCTTTGGGACTCACACAGACTCAG
Seq A exon
GTACCTCGCCGCTGCCGCTCCGTTCTGCCACGCAGGCTTTCCGCGGCCGGCCTGCGCCCGGGTCTTCATTTGTTGCTCGCTGGGACTCAGGGTCGGGGTGTCACTGTGTGTATGTGTTTGTGTCCACCCCTGGCTCTCAGCGTGTCTCCTTCCTCCCTCATTCCCTCTGCCCTAGCTCTGTCACTGCTCTCGGTATCCCGAGCTGCCTGCCGTCCGGCCCTCTGTCCCTGGACAATCTGATTAGGGCGCAGGAAGGATTTCCCCAGACGATTTGTTTGGGAACTCAGAGGTCACACGTGCCTAAACAACTGGAACAATAGACTCCGGGCTTAATCCCTCCTTTGCCTTTAAATTGTGTGACTAATCACTCGGGGCCTGGGTCCGCGCCTCAGCCTCCCTCCTCCTCCTCCTTCTTACCGGTTGGGGGTGGGGGGAGATCCTTTCCTCCGCCCTCTCACCTCTCAAGTCCCAGACCTTAGAGAAGAAACGGGACCTTCCTTCCCGGCTTTCTGTAAGACTCCGGGGAGCCCGTGAGCGTTCCTGACGGCGGCGGGCGCGGGTTTCCGACGTCCGGTCCGGGATTTGGAGCAGAGCTGGAGAAAGCAAACAGACACTAGTGCAAGAATGGTTTTGAATCCAAAGAGAAGTTCAGCAAAACCTTGAGGCCTCCTTAGTCCGTCCCAACTCAAGGGCAGAAAAGATGGCGCATAGAAAAGTTGGGTCGCGTTGCAAATAAATTTCCTCCACTCCTTCCTAGGTTTTCGATTCTTTTTATTGATGTTGATATTGGAATTGCTGGCTCGGTGTTATGCAGGCGCTGTATCTTCCGCAGGCGGTAGCCACGGTCGGACTGAGCCCCTGGCAGGCTAAGGCCTGGATCCCGGTTCTCCCCTCATCACAACTCCTCCCTGGCTCTCTGAGAGCTGCCCCCGTGGGCTGACGGCGGCGGGAGGTTCGGCCTTCGAGCCTTTGGCTCTTATGGGGGAAGGGAGGAAGGAGGGATGTCTCTGCTTCTCTGGCAGGGAGCTGCCAGCTGGCGCAGGGTTGGGAGGTCCTATCTCTGCTGTTCTGCGGTCCCTTTTTTCCTCCCTGTGACCTAGGTAGGCTCAGTGGTCCCAGCCTGAGTCACGTTGTTGTCCGCTCTTGCAG
Seq C2 exon
GTCAAGATCTGGTTCCAAAACAAGCGATCCAAGTTCAAGAAGCTGATGAAGCAGGGTGGGGCGGCTCTGGAGGGTAGTGCGTTGGCCAACGGTCGGGCCCTGTCTGCTGGCTCCCCACCCGTGCCGCCCGGCTGGAACCCTAACTCTTCATCCGGGAAGGGCTCAGGAGGAAACGCGGGCTCCTATATCCCCAGCTACACATCGTGGTACCCTTCAGCGCACCAAGAAGCTATGCAGCAACCCCAACTTATGTGAGGTTGCCCGCCCGTCTCCTTCTTGTCTCCCCGGCCCAGGTCCCTCCCGCCTCCAGGTCCATCCATCCCGTCCGGAAAAGAAGGACCCAGAGGGAAGAAGGAACAGTGGAGGCGGGACGCCCTCCATCTCCTCGGAGCCCCGCGAGGTCCGGCCCAGCAACTTCCCGGCATCCGCGCTCTAGCCTGAACCCTGGCCTGGGCCGAGCAGTGGCAGCAGAGAGTGGCCTCGGAGGGAAGCCACTGCCACCTGAGACAGCCCAAGCAGCAAGATAAACCCGCTCCACCCGACCCGCCGACCTTCAGCTTTGTGGGACTATCAGGAAAAAACAAAACAAAAACAAAATGTAGAAAAAGCAAAAGCTCTTTTCTGTCCTGTCAGTCTCCTGTCTCCTTTTGCTCTGTCTGTGCGCTGGTAAAGTCCAGGTCCTCATCCGTCCGCTGTCCTCATTCTGCGGCCTCAGCAAAAAGCCACAAGGTCTGAGCGGCCCGGGTCCTGCCGGGCTGACCATCTCCGGATCCTGGGACACTCTGCCTGACCATCTGTGTAGCTGGTGTGGGAATCTGGGGGCATTGGAGGGAGGGGGTTTTATTTATTGAGAAATGGACTTCGCCTGAGGCTGTTTGCCAATTCAGGGTTCTGCTGGGCGCAAGGAACGCACTGTTCAAACGCACTGTTTACTTTAAGCGCACGGGGAGAAACGAATAAGGAGGACGTGGTGATTTTTAATTTATACAGTAACTTTTGTACTTCTCTGGTATGGAGAGTTTGGAGCCGAATGATTTGCATTTTTTACATGTCCGACATTATTTAATAAATAATTTTTAAAAGAAAAGAACGATAAATGAAGCCAACATGATTTTCTCATTTCGGGAGGAACTCTGTTGCTTCGCCTGGACAAGAAGGAAAATGCTGATTTCCTCCTTGGGTAGAAAGAGGGAGCGAGGGCAAATGGGGAGTAGAGAGAAAACAGGCGAGAACAAGCACTCTAATTCCAGTGGGCTTTAAAATAAGACAAAATCAGCTTTACAACAATCCCTAGAGGCTCGACCACAGAATAATGCCAGTCACCACCCTGAACGCACAATCTCCAGTGCAGGATCTAATGACTGTACATATTATTGTTATTATTATTATTGTTATTATTGTTGTTCTGTAAACATGTTGCACAAGCTTAGCCTTTTTGCGTTCTGTTGTGTGTGGCTGTAAAACCCCATGCTTTGTGAAATGAGAATCTTGACATTTTTCTTGTGAAATTTGGAAAATGTGATCAATTGAAATCAACTGTGTTTTGTGTTCTCTATGTCAAAGTTTAGTTTTATATTGAGAATGTTAACTTATTGCTTTGTATCTTGGGAAAAAAACTTTGTAAATAAGTTATAAAGTTTCTTTGAGACAGTAAAATTATGATTTCTTGAAAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144355:ENST00000361725:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.351 A=NA C2=0.595
Domain overlap (PFAM):
C1:
PF0004624=Homeobox=PU(73.7=62.7)
A:
PF0004624=Homeobox=WD(100=63.2)
C2:
PF0004624=Homeobox=PD(22.8=15.3)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTCAGTACCTAGCTCTGCCG
R:
GGGAGACAAGAAGGAGACGGG
Band lengths:
351-1500
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains