HsaINT1012934 @ hg38
Intron Retention
Gene
ENSG00000131187 | F12
Description
coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]
Coordinates
chr5:177405735-177406061:-
Coord C1 exon
chr5:177405962-177406061
Coord A exon
chr5:177405806-177405961
Coord C2 exon
chr5:177405735-177405805
Length
156 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGA
5' ss Score
9.45
3' ss Seq
AGCCTTGTCTCTTTCTACAGGTG
3' ss Score
11.15
Exon sequences
Seq C1 exon
TTCTCACTGTCACCGGGGAGCCCTGCCACTTCCCCTTCCAGTACCACCGGCAGCTGTACCACAAATGTACCCACAAGGGCCGGCCAGGCCCTCAGCCCTG
Seq A exon
GTAAGACTACGCAGAGGAGTTGGAGCAGGGGCCTGGGAGACATGTACCCTGCCTGTCCTTCTGTCCAAGGAACTCTGCTTGGAGAGAGGGGACTGTGATAGGGCAGGGTGGGCCAGGCCCCTGGGTAGAGCAGGGAAGCCTTGTCTCTTTCTACAG
Seq C2 exon
GTGTGCTACCACCCCCAACTTTGATCAGGACCAGCGATGGGGATACTGTTTGGAGCCCAAGAAAGTGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131187:ENST00000253496:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.029 A=NA C2=0.100
Domain overlap (PFAM):
C1:
PF0004014=fn2=PU(59.5=73.5)
A:
NA
C2:
PF0004014=fn2=PD(38.1=64.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCTCACTGTCACCGGGGA
R:
CTTTCACTTTCTTGGGCTCCA
Band lengths:
171-327
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains