HsaINT1015512 @ hg38
Intron Retention
Gene
ENSG00000159399 | HK2
Description
hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]
Coordinates
chr2:74878688-74880569:+
Coord C1 exon
chr2:74878688-74878921
Coord A exon
chr2:74878922-74880264
Coord C2 exon
chr2:74880265-74880569
Length
1343 bp
Sequences
Splice sites
5' ss Seq
CCAGTGAGT
5' ss Score
8.28
3' ss Seq
CCCGCCCTGGGGAACTGCAGTTT
3' ss Score
1.21
Exon sequences
Seq C1 exon
GGAGAAGGATGGCATCCGGAAGGCCCGTGAGGTCCTGATGCGGTTGGGCCTGGACCCGACTCAGGAGGACTGCGTGGCCACTCACCGGATCTGCCAGATCGTGTCCACACGCTCCGCCAGCCTGTGCGCAGCCACCCTGGCCGCCGTGCTGCAGCGCATCAAGGAGAACAAAGGCGAGGAGCGGCTGCGCTCTACTATTGGGGTCGACGGTTCCGTCTACAAGAAACACCCCCA
Seq A exon
GTGAGTCAGTGTGCAGGGCCTGGAGATGCGGAGTTCCTGGAGTACCTGGGGCTGAGTGACTCCTCATGCCAGCTCCATTTTGCATTTCAGGGGTGGTGTGGAGGGACCATAGAGCTGAGGGTCTTGGTGGAATGAAAGTTCCCACCTGGGCAAGGGGGAATGGGAGGAAGTCATATCTGGTGTGGGTGGAGGTGATTTCTGAAGGCTACTGATGACTCGGGCTCTCCGCAGAGCTCCTCTGGCTGCTGGACACTCTCTTTGCCACCCTCTTGTATGCGTTATTGTTCCTGTCTTTACTCTTAGAATTCTTGGTGATTCCTGCAGGTGCTATGTCCTCTGCCAGGGACCACCCCAGCCCAGTGAGGGTTACCAGCTTCTCTGGCTGACCTTGGTATTAAATTGATCCTGCCCTGTCCACATTTTGATCCCTCAGGTCATAGGTACCAGAATATTCACATGTCAGCTGAGACCTGGAAGATGTCTCTTTATTGTGCCTACTTATTTCCCCATCATTTTCACCTAATAAGAATGCCAGGTCAATGTGCCTTTGTTTTCTTAACTTGTCGGTGCAGGAGGCCTCAGCCCTGAGATTCCCTCTTCCTACCCAGTGTTGCAAAAACTCGAGTGTGCACGTGAATCACATGGGGATCTTGCTAAGAGGCAGATTCTGATCAGAAGGTCTGGGGTGAGTCTGAGATCCCGCATCTCTAACAGCCCCCAGTAGGCTGCAGCCTACTCCTGCACTTGGAGTAGGAAGGCCCTGGAGACCATGGCTCCAAGTGGCCACTACCCAGAGAGTTCCTGGCTGAACACGTTGTCTTTAGCTGTGCAGACACCTTTGGGATCATTGGCAGAAACTGGCAAAAGAGAGGCTAAAGTCCAGAAGAGCATCTCTAGCTTTTAATTTTGGGTCTTTCCCAGACAGCAGCTAGTGAAATGAGTGATAGAACAAGACAGATAGGTGGCATCAGAACCACCTAATACCACAGGGCTGCTCCAGCAAAGAGGCTGATGGTACCATGTTGGGCAAGGGAGCAGTGGCCAGGGGGCCTTCTTCAGTGAGGAAGAGGAGGTCTTGTGTGGCTGCATGTAGGGGACAGTGGCTTATTAAAAGGTCTTTTCCTTTCATTGGCGGGGGTGAACCAATCCTGGGTGGTCATAGTTGATATGGTTCTTGTAGTGGTTCCTAACTTGGGACAGTGGAGAGAGGATGTTTAGGGCAGCACCCACTCCTGCAGGTGCCTTTTGGCATTTGGATTAAGGCGGTGGGCAACTGTCTAACTATTTGCACCATTGACCCTAACCATGGACACCTGTCTCTTACCCGCCCTGGGGAACTGCAG
Seq C2 exon
TTTTGCCAAGCGTCTACATAAGACCGTGCGGCGGCTGGTGCCCGGCTGCGATGTCCGCTTCCTCCGCTCCGAGGATGGCAGTGGCAAAGGTGCAGCCATGGTGACAGCAGTGGCTTACCGGCTGGCCGATCAACACCGTGCCCGCCAGAAGACATTAGAGCATCTGCAGCTGAGCCATGACCAGCTGCTGGAGGTCAAGAGGAGGATGAAGGTAGAAATGGAGCGAGGTCTGAGCAAGGAGACTCATGCCAGTGCCCCCGTCAAGATGCTGCCCACCTACGTGTGTGCTACCCCGGACGGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159399:ENST00000290573:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.049 A=NA C2=0.105
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=FE(32.5=100)
A:
NA
C2:
PF0372711=Hexokinase_2=PD(16.7=38.8),PF0034916=Hexokinase_1=PU(29.1=58.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATCTGCCAGATCGTGTCCAC
R:
ATCCTCCTCTTGACCTCCAGC
Band lengths:
354-1697
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains