HsaINT1022856 @ hg38
Intron Retention
Gene
ENSG00000123600 | METTL8
Description
methyltransferase like 8 [Source:HGNC Symbol;Acc:HGNC:25856]
Coordinates
chr2:171337453-171339554:-
Coord C1 exon
chr2:171339184-171339554
Coord A exon
chr2:171337503-171339183
Coord C2 exon
chr2:171337453-171337502
Length
1681 bp
Sequences
Splice sites
5' ss Seq
GAGGTATTG
5' ss Score
7.44
3' ss Seq
GCTTGTTCTTTTGATTTTAGGTT
3' ss Score
9.77
Exon sequences
Seq C1 exon
TTAAGTATGAGAGAGAAGCTAGTAAATACTGGGACACATTTTACAAGATTCATAAGAATAAGTTTTTCAAGGATCGTAATTGGCTGTTGAGGGAATTTCCTGAAATTCTTCCAGTTGATCAAAAACCTGAAGAGAAGGCGAGAGAATCATCATGGGATCATGTAAAAACTAGTGCTACAAATCGTTTCTCAAGAATGCACTGTCCTACTGTGCCTGATGAAAAAAATCATTATGAGAAAAGTTCTGGTTCTTCAGAAGGTCAAAGCAAAACAGAATCTGATTTTTCCAACCTAGACTCTGAAAAACACAAAAAAGGACCTATGGAGACTGGATTGTTTCCTGGTAGCAATGCCACTTTCAGGATACTAGAG
Seq A exon
GTATTGTGCTCAAGGGACAAAAATGGGAGGTGACAAATAATTTGAAAATGTACATTCTGTATTATTTTATTAAAAATCCAGATTTTTTTTGGTGGAAAACTATCAAATGTAAATAAGCATTCAGTGTACTTCTGTGCATAAATAATATCTAAGGGACTCATGTCTTTAATCAGTCAAGTTTTAAGTTTGTGGTTTAAATCTGGTTTTGCTGGTTTTTAAAAAAAAAAAAATTGTCTGTTTTCATTTTAATCTGAGGGCAGTTTTAAGTACCAATGAAGCTTTGGCCTTAATTTTTACTCTCTTTGTTATTACCCCTTTTTAGATGAAATAGAAATAAGTGAGATATATAATTTGCTATAATCTGGTGTAGACCTTGGTTTTCTATTTTTAAAACTAAACCCTGTCTTTCTTATTTTAAAGGCAATGTATATTGATTATAGAAAATTTGCTAACAAGGAGATAATTTATCACCAATCCTACAAACAAAGGATTTCACCACTGTTAACATTTTAGTGACCTTTTTCTTCTTTTTTTTTTTTTTTTGAGACAGACTTTTGTTCTTGTTGCCCGGGCTAGAGTATAGTGGCGCCATCTCAGCTCACTGCAGCTTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGTCTCCTGAGTAGCTGGGATTACAGGCGCCTGCCACCACACCCAGCTAATTTTTTTGTATTTTTAGTAGAGACAGGGTTTCGCCACGTTGGCCAGGCTGGTTTTGAACTCCTGGCCTCAGGTGATCCGCCCGCCTCAGCCTCCTAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCTGGCTGACCTTTTTCTTCTTTTATTACTGTACATGTATTCTAAGTTTTGTTTGTTTCTATTTAACATGGCATCATAAGCAGTTTTCACTATCTTTAAAAATTCTCTGTAAATATTTTGATGGCTACAAAATATTTTACTATGTGGAGTACTATAATTTTACTTATCTATTTTCACACTACTGGGCATTTTAATTGTTTTCAGATTTTCTGAAGCAAACATTTTGGGTATAGCCTTTACCTGCATTTTCTTTTATTGTTTTAGGTTAGATTTTCTAGTTCATAATTTATGAAGATTTTTAATACTTTTAAAACATATTGCCCACTTGCTTTCTAAGAAGTTGTACTAATACCATTCCATGACAGTGTATGTCTGTTTCATCACACCCTCATTGATTGAAGTATTATTTTAATGTTTTCCACTTTGTTAGACAAAAATTGTACCTTGTTTTAATATGCGTTTCTTTGATGACTAAGTAGGTCACATACTTCAAATGTTTAGAATCATTTGTACTTCTTTTTTGTTCTGTCCATTTATTTTCTCTGCTTATCTGTTTTTTTTTTTTTCCTAATGAGCCTTGCCCTTTATCATATTCATTGCAGTTTTCTTCACAGCGTATTGGTTATTTTTAAATTTGGTTTATTTTGGGTTTTGGTGTGTAAAAAATTTAAATGTTTCCATAGTCAGATTTCTTAGTGTTTATTCCTGTGATTTATTTCATTGCTTTTGAGTTTAGAAAATTATCCTGTGCCCAGAGATCCAGTAAGTCTAATTGTTTTTTTCTTTAATAGGAGATCTGACATTGGTGACAAAAATTTAACCTTGCTTTTTTTGATATTTGCTTGTTCTTTTGATTTTAG
Seq C2 exon
GTTGGTTGTGGAGCTGGAAATAGTGTGTTTCCAATTTTGAACACTTTGGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123600:ENST00000375258:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.447 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF134891=Methyltransf_23=PU(10.4=80.0)
A:
NA
C2:
PF082427=Methyltransf_12=FE(15.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGTAATTGGCTGTTGAGGGA
R:
AGTGTTCAAAATTGGAAACACACT
Band lengths:
343-2024
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains