MmuINT0098068 @ mm10
Intron Retention
Gene
ENSMUSG00000041975 | Mettl8
Description
methyltransferase like 8 [Source:MGI Symbol;Acc:MGI:2385142]
Coordinates
chr2:70980377-70982195:-
Coord C1 exon
chr2:70981855-70982195
Coord A exon
chr2:70980427-70981854
Coord C2 exon
chr2:70980377-70980426
Length
1428 bp
Sequences
Splice sites
5' ss Seq
GAGGTACTG
5' ss Score
7.67
3' ss Seq
TTGTTTATTCTCAATTTTAGGTT
3' ss Score
12.25
Exon sequences
Seq C1 exon
TTAAGTTTGAAAGTGACGCTAACAAATACTGGGATATATTTTACCAGACCCATAAGAATAAGTTTTTCAAGAATCGTAATTGGCTGTTGAGGGAATTTCCTGAAATCCTTCCTGTTAATCAAAACACTAAAGAGAAAGTGGGAGAATCATCCTGGGATCAAGTCGGAAGCAGCATCTCTAGGACACAAGGAACAGAAACCCATTGTCAAGAGAGTTTTGTCTCGCCAGAACCTGGGAGCAGAGGACGGTCTGCTCCTGACCCCGACTTGGAAGAATACAGCAAAGGACCTGGGAAGACAGAGCCGTTTCCTGGTAGCAATGCCACTTTTCGAATACTAGAG
Seq A exon
GTACTGTATGAGAGTGTGTAGCCCACGCTATTTTATGAGTGGTCCAGACTGTCCAGGTGGAAAGATCAGATCTAATTAAATGCTTAGTGTTCTTACATGCATAAGTAATACTTCAGGGACTTTAATCAGTCAAGTTTTAAGCTTGTGGCTTTAATTTCATCTATGTTACTTTTTTTTTTTCTTTTAATTTGTTGTTATTTCTAACTTAGAGGCAGTATTTAAGTCCTGGTACATTTTTGGTCCAAATTTTTGCTCTGTTTTTACCCCACTTGGGGTGCAATAAAAATAAGCAAGGAGTTTAGTTTGCTGCAGTCTAGTGTAGACAGTGGTTTTCCATTTTTGAACCTAAACCCCATCTTTCTGACCCTAAAGGTAATAGTTGTTGATTACAGAGAATTTTCGGGTGAGGTCATAAGAGAAATACAGTTAGCCACAATCCCACGGCCAGGCTGTTTAACCGCCTTTCCTGCTTTTGTTTAGGCTGTGCATGAGCCTTGAGACTTTGTGCTGTTCTGTTTAACATCACGTCATACGCAGTTTCCACCTTTAATTGTCCTCCGTAAACACCTCTGTGACTGCACAGTATTTTGTGGCTGGGATATTATAATTTTACTTACCTGCTGTCACGCAGGGCATTTAATTGTTTCCTCAGCAGATGTCTTTGGGTATAGACTTTACCTGCATTTCCTTTTCCCATCTTAGGTTAGATTGACTAGTTTACAATATTTGGAATTTTTTTAGAGGTCTTAGAATCTGTTTTAAGCTATATAACACCACTAGGTGTGGTGACACGAACACACAGGAAACAGAAACAAGAGTGATAGACATGTTCAAGGCCAGCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCTCTTTCTCTCTCTCTCTCTCTCTCTGACACACACACACTGGGGTTTGGACCGAGGGCCTTTCACATGATAGGCAAGAGTTCTACAATCCAGCCCATTTTCTGAGTTGCCCTGATGTGCTCAGACTCACTGTGTAGTGCAGTCTTCTTGTCTTGGCCAAGGTCCAGGCCCCTTTTACCCTGGTTTGGTTTACACATTGCCCACCACTCAGTATACCTCACAGCTCTTCACCGAGAACCACACGTTCTTCATTTGTATTCTGTCCGTTCCTTCCCTCTGCTGTCTATGAGTCCTTCCCTTTACCACAGCTGCTGCAAGCACTTCATTGCCACCTTGGTGTCCTGTCCTGCGTGGTTCACTTGCTGATTGAGTGGGAGGGGCTTTGGTGGGCACAGACTGTGAATGTCCCCACAGTCTGACGTTGATTGTCCCTCCTGTGCTTTGTTTCACAAGTTCTGCCACACCCAGAAATCCATAGAAAATCCAGTATTGTGAGAGAAATGCAATGCGCTCACATTTGTTTATTCTCAATTTTAG
Seq C2 exon
GTTGGCTGTGGTGCTGGAAATAGCGTGTTTCCAATCCTGAACACCTTGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041975:ENSMUST00000112186:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.529 A=NA C2=0.088
Domain overlap (PFAM):
C1:
PF134891=Methyltransf_23=PU(15.8=26.3)
A:
NA
C2:
PF082417=Methyltransf_11=FE(17.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTGACGCTAACAAATACTGGGA
R:
ACGCTATTTCCAGCACCACAG
Band lengths:
356-1784
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types