HsaINT1024053 @ hg38
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]
Coordinates
chr16:15724888-15727054:-
Coord C1 exon
chr16:15726848-15727054
Coord A exon
chr16:15724993-15726847
Coord C2 exon
chr16:15724888-15724992
Length
1855 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
CAGTCTCTTGGCACCCTTAGAAT
3' ss Score
4.66
Exon sequences
Seq C1 exon
GCCAAGGCGAACCTAGACAAGAATAAGCAGACGCTGGAGAAAGAGAACGCAGACCTGGCCGGGGAGCTGCGGGTCCTGGGCCAGGCCAAGCAGGAGGTGGAACATAAGAAGAAGAAGCTGGAGGCGCAGGTGCAGGAGCTGCAGTCCAAGTGCAGCGATGGGGAGCGGGCCCGGGCGGAGCTCAATGACAAAGTCCACAAGCTGCAG
Seq A exon
GTGAGGAGGTGGCGCGGTGGTGTGGTGGGCAGTGCTGGGTGGTGCCCAGTTCTGTGGGGAGGAGCCTCTTCCCGGCTCGCTGAGGTCTCTCTTGCTGCAAGGCAAGTCCTTTCCTCTAGTTGCGTTCCTGGAGGAGAGGCGATGATCTCCCTGTTCAATTAAATATTAAAAAAACCTTCTGGCCAGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGACAGAGGTGGGTGGATCACCTGAGGTCAGGGGTTTGAGACCAGTCTGGCCAACATGGTGAAAAGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTCGTGGGCACCTGTAGTCCCATCTACTCGGGAGGCTGAGGCAGGAGAATAGCTTGAACCCAGGAGGCAGAGGTTGCAGTGTGCGGAGACCGCACCATTGTACTCCAGCCTGGGCTAAAAGGGCAAAACTCTGTCTCAGGAAAAAAAAAAAAAAAGAAAAAAAACCCTTCCTTTTCCAATTTGATAAGTATTTATTGAGCACCTGCTGTATGCCAGGCACTGTGCTTAATCCTGAGATCCAACAGCAAGGAAGAAGAGACACTGTCGCTGCCCCAGTAGGACTCCAGCCGAGTAAGGGGAAGGGAAGGGAAGGGAAAGACATGAATAATCACACAAATGAATGTCAAATGATGCAGCAAAGGGAAGGCACATGATGCCCAAGTGTAAATAACCAGGGGGCCTAACCTGGGGGAGGAGGAGCCACGAAAGGCTTCCCTAAGGAGCATGGATAAGTCTACCAGGCAGAGGGAACAGCGTGTGCAAAGGCCCTGTGGTAAGTAGAAAAATTAGGAGAGAGACATACAGCCAGTAGAGCTGGAGTGCCCAGCTGGGGTTGGGGGTAGGGGGAGATAGTACAGAGTGGGGTTGGAGGGGGAGCTTGTACCCAGATGATGTAGGGCTTTTGAGAACCTATTACATGTATGTTGATCCTTACTCTGGGCAATGTGAAGCTGTTGAGGGGTTTTAAGCTGCTGAATGACATGGTCTTTTTGTCTTTGGTCTTCTTTCACTTGGCATAGCCATTTACCCTGCCTTGCCACTCATGGGGACGTGGCCAAAGTTTTCACAAATGTTTAACATGTCCACAGCCAGGGACCAAGGGGCGAGGGAAGAATTAAGTGAGATGTTTTTTTCTCACATGCAGTTGAGAGCAGGGCTTTTGCCGCCCTCATATAAGCAGTGTCAAGATCATTCATATCCTCCTTGTCAATGGAAGAGATGGAGGGGTAGGCTAACAGCCTCAAAGGGACTTATGCAGAGACACTAGGGAGTAAAAGCCAGAGAATACAGAGAGGACGTTTTTACCTTTAGGGCCTGCGTCTCTGGCTTTGGCCATCAGGGTCAAAGAGTAGGAGTGAGGAAGGAAGGGATGGGACAGCATCCCTGGGACGTTCAAGTACCATCCTGGTCTCCCTTCTCCAGCCTTAGAGAGTGGACCAGCCAGAGCACCTCGTCTGGACTCTCAGACCTGCTGCTTTGTCTCTACCAACCTTGGCAGGGATCTAGGATCCATTTAGTGGGATCAGGTCCCAGTCAATACCATTGGGGCTCAAATAAGTTCTTAGAACCACAGAGTCTAGGGCCAGGGTCCCAACTCATAGGTGACGGAGTTCCCTTCAAGCCACAGATTCTGTTTTTTTTGTGTGTGTGTGTGTTTTTTTTTTTTTTTATCAGAGTCCCATACCTCACGGGTATTTTCTCAATCAGTGAACACCTCAAGTACTAGCCCATGTGTTTTGAGTAAAAAGGGCTCCTTTCAACGAGGATCCCCTTCTAGAGGCTTTGACTAACCAGTCTCTTGGCACCCTTAG
Seq C2 exon
AATGAAGTTGAGAGCGTCACAGGGATGCTTAACGAGGCCGAGGGGAAGGCCATTAAGCTGGCCAAGGACGTGGCGTCCCTCAGTTCCCAGCTCCAGGACACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392:ENST00000300036:28
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.986 A=NA C2=0.457
Domain overlap (PFAM):
C1:
PF0003816=Filament=PD(24.7=87.0),PF0157614=Myosin_tail_1=FE(7.9=100)
A:
NA
C2:
PF0003816=Filament=PD(1.9=14.3),PF0157614=Myosin_tail_1=FE(4.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCGAACCTAGACAAGAATAAGCA
R:
TGTCCTGGAGCTGGGAACTG
Band lengths:
302-2157
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains