HsaINT1024114 @ hg38
Intron Retention
Gene
ENSG00000264424 | MYH4
Description
myosin heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:7574]
Coordinates
chr17:10451326-10452330:-
Coord C1 exon
chr17:10451941-10452330
Coord A exon
chr17:10451453-10451940
Coord C2 exon
chr17:10451326-10451452
Length
488 bp
Sequences
Splice sites
5' ss Seq
AAGGTCTTC
5' ss Score
0.45
3' ss Seq
TTTTCTACCTCTCACCCCAGGCA
3' ss Score
9.56
Exon sequences
Seq C1 exon
GCCCGCATTGAGGAGCTGGAGGAGGAAATCGAGGCAGAGCGGGCCTCCCGGGCCAAAGCAGAGAAGCAGCGCTCTGACCTCTCCCGGGAGCTGGAGGAGATCAGTGAGAGGCTGGAAGAAGCCGGTGGGGCCACTTCAGCCCAGATTGAGATGAACAAGAAGCGGGAGGCTGAGTTCCAGAAAATGCGCAGGGACCTGGAAGAGTCCACCCTGCAGCACGAAGCCACGGCAGCTGCTCTTCGGAAGAAGCACGCAGATAGTGTGGCTGAGCTTGGGGAGCAGATTGACAGCCTTCAGCGGGTCAAGCAGAAGCTGGAGAAGGAAAAGAGTGAGCTGAAGATGGAGATCAATGACCTTGCTAGTAACATGGAGACTGTCTCCAAAGCCAAG
Seq A exon
GTCTTCATTAACTTGTGCCCTTTTCATCTTTATTTGCAACAATTCAAAATGACCAAGTTTATATATGACTATTTTTAGCCAAATTACACAAACATTAGATGGCATCTGAAGCTTAAACTTACTCCTAGTACACATTATTGTATTGAATCACTTAAGTTCTCTTAACTTCTTTGTAGAAAACACTTTAACCTTTGATACTATTACCATGAAAAAAAATGTAATTACAAAAAAGGTTTATCTAAAAACCATACTCTAAATGATGCAGAATTTAAATGATGTTCACACTTTCAAAGAGAATATAATTTTGATAATCATGTGTTCATTATTTAGCCAAATTAAATGCCTCTACTACTTTATAGCCACCATGCAAGATTGATAGAAAAGTAAATAAAAATCAGCCCCTTTCCACAGGTAGTTACAGATCTCTAAATCCCAGCCTCTAGAATAAAAATGTATTGTCTCTTCCTGTTTTCTACCTCTCACCCCAG
Seq C2 exon
GCAAACTTTGAGAAAATGTGCCGCACCCTAGAGGACCAGCTTAGTGAAATAAAAACAAAGGAAGAAGAGCAACAACGCTTAATAAATGAGTTGTCAGCCCAGAAGGCACGTTTACACACAGAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000264424:ENST00000255381:27
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.915 A=NA C2=0.721
Domain overlap (PFAM):
C1:
PF087025=Fib_alpha=PD(16.4=14.6),PF0157614=Myosin_tail_1=FE(15.0=100),PF0003816=Filament=PU(21.1=23.1)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.9=100),PF0003816=Filament=FE(29.6=100),PF059116=DUF869=PU(30.4=65.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAGGAGATCAGTGAGAGGC
R:
TAAGCTGGTCCTCTAGGGTGC
Band lengths:
342-830
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains