HsaINT1024115 @ hg38
Intron Retention
Gene
ENSG00000264424 | MYH4
Description
myosin heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:7574]
Coordinates
chr17:10450777-10451452:-
Coord C1 exon
chr17:10451326-10451452
Coord A exon
chr17:10450896-10451325
Coord C2 exon
chr17:10450777-10450895
Length
430 bp
Sequences
Splice sites
5' ss Seq
CAGGTCAGT
5' ss Score
8.94
3' ss Seq
TGATGTTTTGTCTTCCACAGGTG
3' ss Score
13.12
Exon sequences
Seq C1 exon
GCAAACTTTGAGAAAATGTGCCGCACCCTAGAGGACCAGCTTAGTGAAATAAAAACAAAGGAAGAAGAGCAACAACGCTTAATAAATGAGTTGTCAGCCCAGAAGGCACGTTTACACACAGAATCAG
Seq A exon
GTCAGTAAATAAATAGCATCAACCTTCGGAGAGGTGACGAATGAAAGACAAGCCTTTACCTACCTATCAAATACAAGTAATTTCTCAAGCTCTGTACATTCATTTATCATGTCTTACTTATTCCTCCATCTTTTTATTATGAGACAGTAAAATGCAATGATTCTAAGCGACAATTGGGGAAAAGAATTAAGCTCCCTGGGCTCAGGAGATTTTTTGTGACTCAGCATTACTCAAAAGTTCTCGAATTCTAAAATATCAAAGAAAACTCATACATTTTTTAAAAAGCAAGAAATAACCTTCTCAACATCACTGAAAATCTTGAGGGGTTTTTTCATCATATGAAATAAGAGGGTTACAATGTTATTCCATTCTTTAAATTATTGTTTACCTAGACAACAGAACTAAATCATTGATGTTTTGTCTTCCACAG
Seq C2 exon
GTGAGTTTTCACGACAGCTAGATGAAAAAGATGCTATGGTTTCTCAGCTATCCCGAGGCAAACAAGCATTTACACAACAGATTGAAGAATTAAAGAGGCAGCTAGAAGAGGAGACTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000264424:ENST00000255381:28
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.721 A=NA C2=0.825
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(4.9=100),PF0003816=Filament=FE(29.6=100),PF059116=DUF869=PU(30.4=65.1)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.5=100),PF0003816=Filament=FE(27.5=100),PF059116=DUF869=FE(42.4=100),PF0003816=Filament=PU(11.8=87.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAAACTTTGAGAAAATGTGCCG
R:
CTTAGTCTCCTCTTCTAGCTGCCT
Band lengths:
246-676
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains