HsaINT1024789 @ hg38
Intron Retention
Gene
ENSG00000162614 | NEXN
Description
nexilin F-actin binding protein [Source:HGNC Symbol;Acc:HGNC:29557]
Coordinates
chr1:77917566-77918038:+
Coord C1 exon
chr1:77917566-77917757
Coord A exon
chr1:77917758-77917959
Coord C2 exon
chr1:77917960-77918038
Length
202 bp
Sequences
Splice sites
5' ss Seq
GAGGTTATT
5' ss Score
2.73
3' ss Seq
TAATTTATTTAACCATCTAGATT
3' ss Score
4.87
Exon sequences
Seq C1 exon
ATTCTGCTTTCTTCATCTAAACCTGTCCCAAAAACCTATGTACCAAAACTTGGCAAGGGTGATGTAAAGGATAAGTTTGAAGCCATGCAGAGAGCCAGGGAAGAAAGAAATCAAAGGAGATCTAGAGACGAAAAACAAAGAAGAAAAGAACAATATATTAGAGAGAGAGAATGGAACAGGAGAAAGCAGGAG
Seq A exon
GTTATTTTATTTTACTTTATTCTCGTGAAAATATTTGTTTGCATTTTTTCATTTAAATTGTATTTATTCACATTAACCACATTTCACATTAACTATAACTAAAATACTTTTCTGTATTTGTAACCTAATTTAAACTCTGCATATAATGTGATTTAGTCTAATTTTTGGACATGTGCTCACATTAATTTATTTAACCATCTAG
Seq C2 exon
ATTAAAGAAATGCTTGCTTCTGATGATGAGGAAGATGTATCTTCTAAAGTAGAAAAGGCTTATGTTCCAAAATTAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162614:ENST00000334785:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.927 A=NA C2=0.830
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGCTTTCTTCATCTAAACCTGTCC
R:
CTGTTAATTTTGGAACATAAGCCTTT
Band lengths:
269-471
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains