HsaINT1040630 @ hg38
Intron Retention
Gene
ENSG00000124782 | RREB1
Description
ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449]
Coordinates
chr6:7240438-7247221:+
Coord C1 exon
chr6:7240438-7240602
Coord A exon
chr6:7240603-7246423
Coord C2 exon
chr6:7246424-7247221
Length
5821 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGTG
5' ss Score
6.13
3' ss Seq
CCGCTGTGCTTGCCCCACAGACA
3' ss Score
10.27
Exon sequences
Seq C1 exon
GTCAGAAACCCTTCCCTTGTCAAAAATGCGATGCCTTCTTTTCTACCAAATCTAACTGTGAACGCCACCAGTTGCGCAAACACGGAGTTACCACCTGTTCCCTGAGAAGAAACGGGCTTATCCCCCAGTCAAAAGAGAGTGATGTTGGATCCCATGATAGCACAG
Seq A exon
GTAGTGCCGCCAGGTGAACAAGAACCCAGGAAGAGGGAGAGAGAGGAGTTCGGTTAAGAATTGTAGCAAACTCCAGTCCGAGCTGTGGAGGGGCTGCTTGTTCACTTCTCTGTAGGATTCAGAGCCCACAGCCTGTTAATAGAAAGGCAGGCCCTGCTGATGATTGGGAGGGAGTATAACTCCTGGGTCAGATCGCCTAGACAGACAGCAGAAAACAGTGACAGTGCCCCTCGGTGACTCTCGGGGCTGCTAGGGAAGATCTGTCACCCTCTTGGCAGAAGAGGCCTTTGTTCCCGATGTTGGGAGGTGGGATGTATGGGAAGGCTTACAACTTTAGCCCTGGGTATGAACTCATCTAAAGGGGATGTGAAACCTAAAGGTTTGGGGAGCCTTAGCCGCTGCAGCCTCCTCGGGAGCAGGCCTGGGCTCCCTGGGATATCAGGGTATTGTAGGAACGAGGGGTGCGGTGTTCTTCTTTTCAATAACTCTCTTCCCGGTGTAAGACTGTCCTTGTTTGAAAAAGCACTGTGCATGTCCTTTCTTTAATCACATCTCTGCTTGACCTGAATCCGGGTATTATTCTCCTGTGCTGATGTGTGCTTCCTCCCTCCAGCACCCACAGAGCAATTAACGGCTGCCCGATACGTCTTGTGCCACCTTGTTTCCCTTATAGTTTCTGAATTTACTCATGTCCTCTATCAGTACACTCCATCCGCTCGGACTGCTGGGGTTCTCCATCCTCACCCCCAAGAGCAAACAAAACGAAAGCCAGCCTGCTGCAGGCCACTTAGATATCCCGCCAGTTGGCACTGATTAGTAACAGGGACAGCATCATGGTGCTGGGTCCAGTTTTGCAAGTCTTGAAAACCTGACACTATCTTGTGGCTGCGAAGAGATCCCCCCAGCTGTGTTTTTTTAGGGTTGTATTTGCGTCCTGTGGCTTCTATTCCTCAGACTAGGGTGGAGATGGGGTGCCCTGTAGTTACGAGGCACCCCTGCCTCAGGAGTCAGTGTGGAAGAGGGTTGGGCATTAATCTTAGCCCCTTGTCCTTACCTTGGTTACAGGGGTACAGGGTGTATCTGAAGTGGAGAGGCCACCCTTTGCCCATCTCTACGCCTCCCACTGAGCCCTAGTGAAACCAACTGTGAGTGCTCTTGACTGCCCAACCGCCAGTCTAGATCAGATCCTCTGAGGGTATGAAAGGGTAAGCTGGTTTGTTCACTGCTTCCCCAGCTTCCACTTCCACATAACTCACCAGTATCTTTGAGTGAAGAAAGATGTGGGTGCCCACGGAATCTTAGCCTAACTTGGACCCCTGTGAGCCAAAGATGACCTGGAGTTCAGCCCACTGGAAGCGCACACCAGTGCTGGCAGGCACGCGTTTGCTGCAGACCATCCTGTTAATGTTTAACCATCAGCCGCCACATTACCTGTTAGTCTGGAACATTTTCTTTCATCCTGGTTTAGAAAGCTGCCCTGTGATCTTCCCATAGTGGTTCCACAGTAGCGAAAGCAGCCGGTAACTGAGGGAGCTGAGGGGGAGCCCTTGGGTTTCCATGTTTACAAATAAGTCTTAGTAACTCCGTGCTGGATGTGCATTTTGCATTCAGCTTCTTTATCATAAGGGAGGAACAAAGACTGGGGCTCCTGCTGACATCTGCAGACACAAAGCTGAGTCGGAATTTGTGGTCTTAGCTTCGGTTCAGCACCAAGTGTATTTATAAGTTTGCAGTCATAGGTTTTGTTGTCCAAATCCCAACAAAGCCCTTTCCCACCTCCACCCCACCCCGGAAGTTATATAGGGTTCCTTGAAGGGACAAAGCCTCTAGAAAAAGAAAAGTCACTGAAAGTTGTAATGTGAAACCAGCAAAGAGAAAATACATGTTTGGTTTAGTTGTGGTCACAGTCCATGGTGAGAAAAGGGACTGAGATTTAAGTGGGAGGGAAAAGTTTAGGGAGGCAGAGTTTAGTGATTTCAAGGAGGATTTTAAAATGCAGATGAGCATGATGGACATGGGGTGAAGCCTTCATTCTGGGTTCCCCCCCCCCAGTGAAGTTTAAAAAGTGAGGCTTTGAAGGAAGACCACTTAAAAAAAAGGGGGGGGGGGAAGGAAATGACCAAGGAGGTCCTTGAGGGGTTTTCTAGGCTTGTATGCCTAGGTGGCATTTTCTTAAAATTCCTACACATGTTTTATAATGTAGGTCTGACATTTTTCAGTCTCATAAAGTCCCCCAAAAGAATGCTAAAAATGCCACAGTGGGGGCAGTTCTCCCTTAAAGGTCCATTTTGAATATTCAAATTTCAACTGAAATTCTTCATTCACTGTCCTGGACAGAGAGGCAGCCTGGCCCCCTCTGCCCTTGAGGGATATGCCCTTGGTCCTTCCTCCGATGATGCCCCGTCTTTGTGTTTGTAGGCACCTACATAGGGCTGTTTTTAATTCGTATAAACATGAAAGTGTTTAAGCTCTCCCTTAATGGTGGCCGCCTTTACCAGCCCAGAAGTCCCACATGTCAGCATGGACTACACCTCAGGAAACCCTCTCCATCCTCAGATGCTTTGGGTGGAGTGCAGACACAGCAGCTTCCCCTGCAAAGGCACCCCTGCCAGGTCAGATAATTACTTAGGTTGGTAGTCTGTCACAGTGGTTGAGGCTCATTTAATTTTTAGGAAGCAATAGATCTTTAATTGTTGAGCTGACTAGGGCTGTCTCCACAGTCCTGTAGGAGGAGCTGCGGGTTTATTATCTACCAGGATTCCTTCTGCTTCCTCTAACAGTTTTCTTAGTTGTTGAACAACACAAACCGAGGGACTGATGGGGAGAGGGAAGAACTGCATATTTTTAAGGTAGCATTGCTTATAAAAAGTCATCAGCTCAGCTACCTGCATTTGGGAGTCTGGGTGTTGAGGGCGGGGATTTATACAGCACCTGGCCTTATAAGTTGAGTATTCATGATAGGTGAAGAGGTGAAGTTTTTTGTTCATGAGAATCACTAATGAAAATCAGTTGTTTAGAATGTGAAGGGCACAGCCTACACTGCTAAAACACTCCCCCTAGTGGGAGTTTGGTAGAATACAACCAAGCCCCCTGTGTCCAAAGAGGGAGTTGGCCTTTCATTGTACTCCGGGTGATCTCTCTCCATTATCCGCGCAAAGGAAGGGCCCGAGAGCAGGAACAATTTGATCTTATATTTCTTTGGGTTTTGTTTCAAAATTTATTTTACTTTCTTTAAAGCTCTATCATGTTAAATATGTTCTGTGCAGTTAAAATAATGCATGTTCTTTGCTGAAAAAAAAAAAATAGAAGTGTAGTCTAGGATATACTGGGGACAAAGGGGAAGTAACCAGAGATTAAACCTTCTTTTAAAAATTACCAGTCGGGCGTGGTGGCGCATGCCTGTAATCCTAGCCCTTTTAGAGGCCGAGGAAGGTGGATCACCTGAGGTCAGGAGTTCTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCCACTAAAAATACAAAAATTAGCTGGGCATGGTGGCTCACACCTGTAATCCCAGCTACTTGGGAGGCTGAGACAGGAGAATCGCCTGAACCCAGGAGGCAGAGGTTACGGTGAGCTGAGACTGCACCACTGCACTCCAGCCCGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAATTACTTACAAAGGCCAGCCACAGTTGCTTATGCCTATAACCTCAGCACTTTGGGAGGCCAAGGCAGGAGGACCCCTTGAGCCCAGGAGTTCGAGACCAGCCTGGGCAACATAGGGAGACCCTGACTCTAGGGAGGGAAATTACCCACAAAGCCAGCAAACAAATTGAGCGTTCTGTATTTTTATTGTAGAGTTTATACCAATATCCATTCTATAGATGCTCTCTGTTGAAATGATTCAAGAAAAACGAACATCTAGTTTTTCCTTGGAATGTGGCCCAGACATTGGTGTGCATATCCCAGGACTCATATTCTTTAAGCTTTTGGATAATTTTGCAAAATCATTTCTTCTTTAAAATGTTATATTCACACCATAATATTTCTTTCTGAAACCTCTTGAGATACCCAAACAGTGGCTGCCAAAAAGTGCAGTCAGTGTAAAACTAATGAAATGAAATGATGTAAGTAGCCGCGTTATGCAGATGGCTGTGGGTAAAGCCTAAAGCCCCAAGCAGGTGTGAACAGTAGGTACTGTCTCCTCAGACCTCAGGACGGGGCAGAACCAGCTCCTTACCCCAGCCCTCCTGACCGCCTTGATGGCAAATCATCAAGCATGTGACATTGAGGAGGTGTGATGGATGCAGGTTGACATTGTAGTTACACCTGATCACGTCAAGTGAGAATCCAGGTTAGGTGCGTGAATCTGCTGGCTCAAGGACTGCAATCACATCTGGCCTATTGAGGGAGGGGCATCTCGTACTTGTGCCATAAAACAATGACTTTCATCCACCCAATTATCAGAGGAACTTGAATCCCTGCAGTAATAAATCAGACAGTGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTAGATCGCCTGAGGTCAGGAGTTCGAGACCAGCCTGGCGAACATGATGAAACCCCATCTCTACTAAAAATACAAAAATCAGCTGGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTCTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGTGGAGATCACACCATTGCACTCCAGCCTGGGCGACAAGGCGAAACTCCGTCTTGAAAAAATAATAAAAACTAAATCAGACATAGGATCTGCAGCTAAATAATAGGTCCCACCAGCTTCCAATGTACTGTCGTAATGCATAATTTTAAGAAGTTATTAAGTCTTCTTTCAACCTTAGTAAAGAGAAGGCCTTTTGACACTGTTTGATGTGAATATTGCAGCCGTGCCATCCCTTAAAAGGACTGTTGAAAACTGATAGGCTTTCCACATACAGTTTTACTGGGTGGAATGGACAGATAGGAACAAATCAAGAGGCAGGAAGTCAGGGTAGGTGAGATGCCTGGAACCCAGAACCCCTTGTCTTCACAGGCACCCACAGCCCTTCACAGTCCGCTCCCCTCACTGTGTGCTGTTGCCAAGCCTGGCATCAAGGGTGCCCTTCCTTTGAAAGATTCCACCACCCCTGGGAGGCTGACAGCTAGGAAGCCTACAAGCTTGCCTGCGCCCCCTTGGGTCTCTGCAGCCTCCACCTGGAGATGAGCGTCAGGCAAGAGTGTGCATACCATACACACACAACGCAGGCTTGGGGTCGTTTCCTGTGAAACTCATCAAGACCATGCTTTGGAGGATTAGGGGTAGGGGTGGTCCTGTGTATGTTGCATGTTTGTATGATCTCTTTGCACTGGAAAAATAACTTATAACTCAAGCTTCCTCAACTTCCCTAGCGCTGCGAGTCTCTGGAATGCACCCCTCTCCTATCTCGCAGCCCCTGTCTGCCCTGCCTGAGTCACTCACACCTTCCTGGGGGCGGGGGCAGTGGAAGCCAGGGGTTCAGGGGCACAGCCAGCCCTGGGAACACACCTGAGGTGATGTGGAGGCTGCTTTTGCCTTTCTTCACGTCCCCAGGGTCATCTTGGTCCTCCTGGGGGATGTAACAGGTGGTGAGGATTTGGGCCGAAAGAAGTCCTCACTGGTTTGGGGTTCAGGCTGCTGGCGTGGGTCTAGCCCATTCCCGGCGACATCCCTGGCATGGGCGTACCTGGTGGTGCCCCTCTGAGCCCTCCCCGCTGTGCTTGCCCCACAG
Seq C2 exon
ACAGTCAGTCGGATGCGGAGACTGCAGCCGCCGCGGGCGAAGTGCTAGACCTCACCTCACGGGACAGAGAGCAGCCGTCGGAGGGCGCCACTGAGCTCCGCCAGGTCGCAGGGGATGCGCCTGTGGAGCAGGCCACGGCGGAAACGGCCTCGCCGGTGCACCGGGAAGAGCACGGGCGTGGGGAGAGCCATGAGCCGGAGGAGGAGCATGGCACTGAGGAGAGCACTGGGGACGCCGACGGCGCGGAAGAGGACGCGTCGAGCAACCAGAGCCTGGACCTGGACTTCGCCACCAAGCTCATGGACTTCAAGCTGGCGGAGGGCGACGGCGAGGCAGGCGCCGGGGGCGCGGCCTCGCAGGAGCAGAAGCTCGCCTGCGACACCTGTGGGAAGAGCTTCAAGTTCCTGGGCACCCTGAGCCGCCACCGGAAGGCGCACGGCCGCCAGGAGCCCAAGGACGAGAAGGGAGATGGCGCCAGCACTGCAGAGGAGGGGCCCCAGCCCGCCCCTGAACAGGAGGAGAAGCCCCCCGAGACCCCGGCAGAGGTGGTGGAGTCGGCCCCGGGTGCCGGGGAGGCCCCGGCGGAAAAGCTCGCGGAGGAGACGGAGGGCCCCTCCGACGGGGAGAGCGCGGCCGAGAAAAGGTCCTCAGAGAAGAGCGACGATGACAAGAAACCAAAGACAGACTCCCCCAAAAGCGTGGCCAGCAAGGCAGACAAGAGGAAGAAGGTCTGCAGCGTGTGCAACAAGCGGTTCTGGTCGCTGCAGGACCTGACCCGGCACATGCGCTCCCACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124782:ENST00000379938:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.454 A=NA C2=0.918
Domain overlap (PFAM):
C1:
PF134651=zf-H2C2_2=PD(57.7=26.8)
A:
NA
C2:
PF0009621=zf-C2H2=WD(100=8.6),PF134651=zf-H2C2_2=PU(40.0=3.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains