HsaINT1044648 @ hg38
Intron Retention
Gene
ENSG00000185873 | TMPRSS11B
Description
transmembrane protease, serine 11B [Source:HGNC Symbol;Acc:HGNC:25398]
Coordinates
chr4:68226653-68228884:-
Coord C1 exon
chr4:68228742-68228884
Coord A exon
chr4:68228073-68228741
Coord C2 exon
chr4:68226653-68228072
Length
669 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGT
5' ss Score
9.8
3' ss Seq
TTTTTCTTTTCTTCTTCTAGAAT
3' ss Score
11.9
Exon sequences
Seq C1 exon
GTTCATTTCCAGTGATACTTCAAGAAGACTTTTTGAAGATTATTGACAACAAAATTTGCAATGCCTCATATGCATACTCTGGCTTTGTGACTGATACAATGTTATGTGCTGGATTTATGTCAGGAGAAGCTGATGCATGTCAG
Seq A exon
GTATGTCTAGTTACATTATCCAGTTGTTTTCTCCCAGTTAATCAAATGGAAGTTTTTATCCACATAAAATTTTTTTTGTGTTAATAATACTGACATAGTAGCTTTGTATTTCAATACACTAAAAATGTATTAATTCCATTTATGTACCAGACACTAGCCTACATGCTAGGGACGTGGAGGTGAACACAATCCTGCCCTCACGAAGTTTTCAATCTGGGAATTCATACAAAGAATAACACTTAGAAGAAGTTTACAAGATGAATTTTGTCCTATTTTCTGGGCAACCTGCAGACCTAGAATGTTGTCTTCTCTTTATCCAGAGATGCATCAGGAGTCTGGGCACATGCCTATGCCACTTGTTCCTCAGAGGCTTCATCATAGAGACTTAAGCTCAGTGCAAGCAGCTAAGTCACCTTCTCCATATTCAAGCTGCACTCATTATATAAGTCAAACTCTGGTTTGCTCAAGTCAACATTTGGCAGTTTTAGGCCATATATTCTGGTTTGTAGCTGTCTTGTGTTTTAAAAAAAAGTCCTAAGGGTTTCAGAGTTCTAAGCCCAAAGAGAGTGAATTGGTTTCAGTGCCCAGGAGGTACAGATAACTCCACAGGAGAGGTAAAAGGAAATTTTTTGTTAAGACAAGAAACATTTTTTTCTTTTCTTCTTCTAG
Seq C2 exon
AATGATTCTGGTGGACCACTAGCTTACCCTGATTCCAGAAATATCTGGCATCTTGTTGGAATAGTAAGCTGGGGTGATGGATGTGGTAAAAAGAATAAGCCAGGTGTCTATACTCGAGTGACTTCTTATCGCAATTGGATTACATCCAAGACTGGACTCTGAAAAAAAAGGAATTATACAAAGGAACATAAAGACCACTGTAGGCTATCCTTATCTGTGGCTTTGGGATCTTTTTATTTTGATTGTTGGTAAACTAATCATTTTATTATATATAAAAATATAAATGTCTTTATTAATATTTTATTATATCTAAAACACTGTCCATGCATTTATTAATCTTTTAAATTAATGTAAGAGATAGGAAGAGGCCAGGTGTAGTGGCTCATGCCTGTAATCCTAGCACTTTGAGAGGCCGAGATAGGCGGATTGCTTGAGCCCAGGAGTTTGAGGGCAGCCTGGGAAACATGGCTAAATCCGTGTTCAAAAAATACAAAAATTAGCTAGGCATGGTGGCGTGCACCTATAGTCCCAGCTATTCAGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAGCAGGTTGAGGCTGTGGTGATTTGTGATTGCGCCACCACTGCACTCCAGCCTGGGCAACAGAGTGAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAGGAGAGAAGAAAATAAAGAAGGCTAATATATAATTTTTCTTAATAGCTGAGTTGTGATTCATTTTACCATTATATTCAGAATTGACCTTAATTTGTTTTCCAGAATCAAAAGAAAATAAAATATAAATTTTGAAACTATGAGAACATATATAGGGGATTTATCAAATGAGTTACTTTTTATTATATCAATTATAATTTCATTTTATTAACTGGAATAAGTGCGAAAGTGTACATTACTTTTTAACTTATATGTGAAATGATTCATGTACCTCACAAAATCATGCAATCTTGCAGTGAAGAAGGAGTATCAGAGCTCCAGCTACACTGAGTCTTTCAATTTACAGATCAAGAAACTGAAGACCAGAGAAGAGAAATGATTTGGTTAAAGTCACTCTCCATCATCTGTGATAAGTTGACAAATTTATCCTTACACAAATTTGTCCTCATTGAGTTGACATCCAAAATTTGTCAGGAATTAAAGAATGACTTTTGAGTGGCAATTATTTATATAACATTTTCCATTGTCTTCATATTCACCTTTTGTCATTTGTTTGCTTTCTCTTGCAGCAAAAATAATATGAGGTCATCAAGGGCAGAGAACTGTGTGGCATCTCCTTATAGTAAAAGTGCAATCATATGGATGGCTAACTTTGTAATCTCTACAAATAATTTACCTTATGTAATTTTCCAAATGTAAAAGTCACCAAAAACTTAAAGGCATTAAAATAAACTAAAAAAGTACTCATTTCTTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185873:ENST00000332644:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(20.8=100)
A:
NA
C2:
PF0008921=Trypsin=PD(20.4=85.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCAGGAGAAGCTGATGCATGT
R:
AAATGCATGGACAGTGTTTTAGAT
Band lengths:
356-1025
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains