HsaINT1044663 @ hg38
Intron Retention
Gene
ENSG00000087128 | TMPRSS11E
Description
transmembrane protease, serine 11E [Source:HGNC Symbol;Acc:HGNC:24465]
Coordinates
chr4:68474723-68476438:+
Coord C1 exon
chr4:68474723-68474761
Coord A exon
chr4:68474762-68476260
Coord C2 exon
chr4:68476261-68476438
Length
1499 bp
Sequences
Splice sites
5' ss Seq
ATTGTAAGT
5' ss Score
8.54
3' ss Seq
CCCCCCTCTCTCTTTTGCAGGCT
3' ss Score
13.05
Exon sequences
Seq C1 exon
AAATCAACAAGACAGAAACAGACAGCTATCTAAACCATT
Seq A exon
GTAAGTTTAATATATTTATTAAAATAGCATTACCTGAAGGTAAAAAGCTAACACTATAGGTCATTTAGGTTTACTTTGTGTTGATATCATAGGGACAGAACACATAAAGTTTGATTAATTTGTGTACAGTTCATGGTACTTTATCATATCTTGGAGATACATTTTATTAGTAAAGGATAGCAAAATTGAGATAACTTTGGAGTGGATGTATGGGTGCCTGTGGCAGATGTGTAGTGGAATTGAGTTGTACAGCTGTTAAAGAAGAGGCAAGAAATGTTTACTTATCAATGTTCTGTTTGTAGATATCTATAAGATAAAACAAATCTATACATTGTGTTTTTCAGCTAGAGGCAGAAACTCATTGTCACTATATCCTAGATAAAATCTTCTTGATGTTATTAATCCTACGGATTAATACGAAAGTGCAGGAAATTATCGGGTCATGGAAGAGTCACAGAAAGTGCAGGAAATTATGGGGTATATTTTAATAAAATTACTGAAGACACATAGATAATATCTTCACCTATATTATAAAAGTGCTGAGTCTAGGCCTAGCATTTTTCTTCGCCTATAGCCAAGTATGCCACCATGATTTACAGTATACATTCAATAGTTATGGGGTTGTTGCACATTACATTTCTCTTAAAAGGTGGAAAAATATGTGCTACTCACCAGCTCATATAGTTGGTTAATTTCTAAAATCAACTAAACACAAAACCAAAAGATAATCTCATTACCTAAATAGCATATATTCTCACCACCAATATTTATTGGGAACCTACCATGTGCTAGCACTGTGTTAGACAACAGGCATTCCAAATGGATAAGATATAATATCTCTACCTGAAGCACCTTATACTTTAATGGGACTAGGTGCATGAGACTAATTCATGAACACATCATTCTTAAACAACACTTCTCAACCAAGGGAAATATTGTTGGCCAAGCTATCATGCCCCACTGTGGCATTTTTGTCATGAATATAGGGGGAGGGCTACTGGCATCTATAGTGGATCTACAGTATATAGGCCAAGATCTTATGATGCACAGGGCAGCCCCCTACAACAAAGAATTAAATGGTTCAATATGTTAGTGGTGCCAAGGTTGAGGAACCCTGTCATAAACAATGTCAGTATGTATACATACACATAAGCACACATACAGAGTGTGTTTGTTATACACATAAGCACACACACAGAGTGTATTTGTTACTATTATTATTTTGGAAGCACCAAGAAAGTAATAACTAATCCAGATTGGAGACAGGGGAGTTAGAGAAAGCATCCTAGAGAGGTAACAACTGATTTAGATTTTACAAAATGAACAGGAGTTAGCTAAATAAAACACTACAGTTTACAGAAAGGTAAGAGCATGAGAAAACATTTGATACTTTTGGAGCACAAAGTAGAAGAAATATGGGACATAGTAACACAATTTGATGTGCAAAACAACTGCTAATTAATGCACCCACCAATGCACCCCCCCTCTCTCTTTTGCAG
Seq C2 exon
GCTGCGGAACACGAAGAAGTAAAACTCTAGGTCAGAGTCTCAGGATCGTTGGTGGGACAGAAGTAGAAGAGGGTGAATGGCCCTGGCAGGCTAGCCTGCAGTGGGATGGGAGTCATCGCTGTGGAGCAACCTTAATTAATGCCACATGGCTTGTGAGTGCTGCTCACTGTTTTACAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000087128:ENST00000305363:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.111 A=NA C2=0.030
Domain overlap (PFAM):
C1:
PF0139015=SEA=PD(12.7=69.2)
A:
NA
C2:
PF0008921=Trypsin=PU(19.5=73.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCAACAAGACAGAAACAGACAGCT
R:
GTTGTAAAACAGTGAGCAGCA
Band lengths:
214-1713
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains