Special

MmuALTA1012268-2/6 @ mm10

Alternative 3'ss

Gene
ENSMUSG00000024335 | Brd2
Description
bromodomain containing 2 [Source:MGI Symbol;Acc:MGI:99495]
Coordinates
chr17:34114428-34115264:-
Coord C1 exon
chr17:34114890-34115264
Coord A exon
chr17:34114473-34114478
Coord C2 exon
chr17:34114428-34114472
Length
6 bp
Sequences
Splice sites
5' ss Seq
AAGGTACCC
5' ss Score
9.16
3' ss Seq
CATGCTGCCTCCTTCTGCAGCGG
3' ss Score
10.59
Exon sequences
Seq C1 exon
AAAAAAGGCGTTAAACGGAAAGCGGATACTACCACCCCTACACCCACAGCCATCCTGGCTCCTGGTTCCCCAGCTAGTCCTCCTGGGAGTCTTGAGCCAAAGGCAGCAAGGCTCCCTCCTATGCGCAGAGAGAGTGGCCGCCCAATCAAACCCCCACGAAAAGACTTGCCTGACTCGCAACAGCAACACCAGAGCTCTAAGAAAGGGAAGCTGTCAGAGCAGTTAAAGCACTGCAACGGCATCCTGAAGGAACTGCTCTCAAAGAAGCACGCTGCCTACGCCTGGCCCTTCTATAAGCCAGTGGACGCTTCTGCTCTTGGCCTTCATGATTACCATGACATCATTAAACACCCCATGGACCTCAGCACTGTCAAG
Seq A exon
CGGAAG
Seq C2 exon
ATGGAGAACCGTGACTACCGGGATGCACAGGAGTTTGCTGCTGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024335-28-31,28-30,28-29,28-28,28-27,28-26-2/6
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact





	

	
Protein isoform when splice site is used (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.619 A=NA C2=0.332
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0043920=Bromodomain=PU(67.4=96.7),PF062846=Cytomega_UL84=PU(24.3=93.3),PF060886=TLP-20=PU(10.6=36.7),PF0105613=Myc_N=PU(0.1=0.0)

							
A:
NA

							
C2:
PF090735=BUD22=FE(13.1=100),PF0043920=Bromodomain=PD(44.9=93.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000025193





     
                   









    
Main Skipping Isoform:
ENSMUSP00000138431





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000092990, ENSMUSP00000109880, ENSMUSP00000117359
          









    
Other Skipping Isoforms:
NA
  



Associated events






Conservation


Human
(hg38)
chr6:32977442-32977570 
ALTERNATIVE
HsaALTA0000979-2/5
(BRD2)
Human
(hg19)
chr6:32945219-32945347 
ALTERNATIVE
HsaALTA0000979-1/3
(BRD2)
Rat
(rn6)
chr20:5266882-5266883 
Cow
(bosTau6)
chr23:7244887-7245015 
HIGH PSI
BtaALTA0004595-1/2
(BRD2)
Chicken
(galGal4)
chr16:92032-92087 
HIGH PSI
GgaALTA1006153-2/2
(BRD2)
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr19:7242510-7242638 
HIGH PSI
DreALTA0006214-2/2
(brd2a)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCTTCTGCTCTTGGCCTTCAT

				
R: 
ATCCCGGTAGTCACGGTTCTC

				
Band lengths: 
93-99

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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