Special

MmuEX0002965 @ mm9

Exon Skipping

Gene
ENSMUSG00000035435 | Abca17
Description
ATP-binding cassette, sub-family A (ABC1), member 17 [Source:MGI Symbol;Acc:MGI:3625331]
Coordinates
chr17:24422561-24426145:-
Coord C1 exon
chr17:24425941-24426145
Coord A exon
chr17:24424675-24424894
Coord C2 exon
chr17:24422561-24422719
Length
220 bp
Sequences
Splice sites
3' ss Seq
TCCCTCTCCTCTCTCTGAAGTTG
3' ss Score
7.98
5' ss Seq
AAGGTAATC
5' ss Score
7.46
Exon sequences
Seq C1 exon
GGGCCCTAAAGGACACTACCTTGTTGTCAACTTTCTTTTTGGAATAGCTTTCCTGTCAAGCTCCTTCTCCATCTTGACAGTCGGAGAGAAGAGCGTTAAGTCTAAGAGCCTCCAGTTTGTGAGTGGAGTCAGCACGGCTGTGTTCTGGCTCTCAGCTCTGCTGTGGGACCTCATCTCTTTCCTCGTTCCCACTCTGCTGCTGGTG
Seq A exon
TTGGTGTTTCTGTGGTATAAGGAAGAGGCTTTTGCACACCACGAGAGCATCCCAGCGGTGGTCTTGATAATGATGCTCTACGGCTGGGCTGTCATCCCTTTGGTGTACACGGTCAGCTTCTCCTTTAACACTCCTGGCAGTGCATGTGTGAAGCTCGTGGTGATGCTCACCTTCCTGAGCATCAGCCCTGTGGTCCTCGTCACCGTCACCAGTGAGAAAG
Seq C2 exon
ATCTTGGCTACACGGAACTCTCAGACTCCTTGGATCATATTTTCCTAATTCTTCCTGGACATTGCCTGGGAATGGCCTTGTCCAACTTGTACTATAACTTTGAGCTGAAAAAGTTTTGCAGTGCTAAGAACTTGAGTGATATTGACTGCAATGATGTTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000035435-'22-25,'22-23,23-25
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF126982=ABC2_membrane_3=FE(16.9=100)

							
A:
PF126982=ABC2_membrane_3=FE(18.1=100)

							
C2:
PF126982=ABC2_membrane_3=FE(13.2=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000046218





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000112538
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr16:2334792-2334926 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr25:1922377-1922596 
Chicken
(galGal4)
chr14:13573101-13573320 
HIGH PSI
GgaEX1005376
(ABCA3)
Chicken
(galGal3)
chr14:14338484-14338703 
HIGH PSI
GgaEX1005376
(E1BVQ5_CHICK)
Zebrafish
(danRer10)
chr3:12527221-12527440 
HIGH PSI
DreEX6015418
(abca3b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GGCCCTAAAGGACACTACCTTG

				
R: 
AAGTTGGACAAGGCCATTCCC

				
Band lengths: 
292-512

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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