Special

MmuEX0006585 @ mm9

Exon Skipping

Gene
ENSMUSG00000027104 | Atf2
Description
activating transcription factor 2 [Source:MGI Symbol;Acc:MGI:109349]
Coordinates
chr2:73680417-73684432:-
Coord C1 exon
chr2:73684254-73684432
Coord A exon
chr2:73683496-73683610
Coord C2 exon
chr2:73680417-73680503
Length
115 bp
Sequences
Splice sites
3' ss Seq
CCTTGTTTTGTTTTTCTTAGTCC
3' ss Score
8.79
5' ss Seq
CCAGTAAGT
5' ss Score
9.09
Exon sequences
Seq C1 exon
GAAGTACCATTGGCACAAACTGCACAGCCCACATCAGCTATCGTTCGTCCAGCATCATTACAGGTTCCCAATGTGCTGCTCACAAGTTCTGACTCAAGTGTAATTATTCAACAAGCAGTACCTTCACCAACCTCAAGTACTGTAATCACCCAGGCACCATCCTCTAACAGGCCAATTGT
Seq A exon
TCCTGTACCAGGCCCATTTCCTCTTCTCTTACATCTTCCTAATGGACAAACCATGCCCGTTGCTATTCCTGCATCAATTACAAGTTCTAATGTGCATGTTCCAGCTGCAGTCCCA
Seq C2 exon
CTTGTTCGGCCAGTCACCATGGTGCCTAGTGTTCCAGGAATCCCAGGCCCTTCCTCTCCTCAACCAGTCCAGTCAGAAGCAAAAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027104_MULTIEX1-5/5=4-C2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.612 A=0.657 C2=0.947
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000058521





     
                   









    
Main Skipping Isoform:
ENSMUSP00000107647





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000058521f2052A, ENSMUSP00000088311, ENSMUSP00000097586, ENSMUSP00000097586f2051A, ENSMUSP00000097588, ENSMUSP00000107636, ENSMUSP00000107638, ENSMUSP00000107641, ENSMUSP00000107648, ENSMUSP00000114828, ENSMUSP00000118560, ENSMUSP00000118719, ENSMUSP00000126034, ENSMUSP00000130822, ENSMUSP00000133632
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr2:175113994-175114108 
ALTERNATIVE
HsaEX0006499
(ATF2)
Human
(hg19)
chr2:175978722-175978836 
HIGH PSI
HsaEX0006499
(ATF2)
Rat
(rn6)
chr3:60747627-60747741 
ALTERNATIVE
RnoEX0012531
(Atf2)
Cow
(bosTau6)
chr2:21796074-21796188 
HIGH PSI
BtaEX6008942
(ATF2)
Chicken
(galGal4)
chr7:16179665-16179779 
HIGH PSI
GgaEX7005958
(ATF2)
Chicken
(galGal3)
chr7:17811128-17811242 
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AAACTGCACAGCCCACATCAG

				
R: 
TGCTTCTGACTGGACTGGTTG

				
Band lengths: 
244-359

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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