Special

MmuEX0008204 @ mm9

Exon Skipping

Gene
ENSMUSG00000026918 | Brd3
Description
bromodomain containing 3 [Source:MGI Symbol;Acc:MGI:1914632]
Coordinates
chr2:27314977-27317263:-
Coord C1 exon
chr2:27317049-27317263
Coord A exon
chr2:27316444-27316522
Coord C2 exon
chr2:27314977-27315348
Length
79 bp
Sequences
Splice sites
3' ss Seq
CTTCAATTTGATCCTCACAGCGA
3' ss Score
5.43
5' ss Seq
AAGGTAAAA
5' ss Score
8.38
Exon sequences
Seq C1 exon
GTTCCCAACAAGTGGCAGCTGTGTCTTCGGTCTCCCCAGCAACCCCCTTCCAGAACATACCCCCCACCGTGTCCCAGACACCCGTCATTGCCGCTACCCCTGTACCAACCATCACTGCAAACGTCACGTCAGTTCCAGTCCCCCCACCCGCTGCACCGCCTCCTCCTGCGACACCCATCGTCCCTGTGGTCCCTCCCACACCGCCTGTAGTCAAG
Seq A exon
CGACCCTCTGGGGCAGGCAGTAGTCCCCCCTCTTACAGATGAGGAAACGGGCGCTCAGGGGTTAAATGGCTCTCCCAAG
Seq C2 exon
AAAAAGGGCGTGAAGCGGAAAGCAGACACAACCACACCCACAACATCTGCCATCACTGCCAGCCGGAGTGAGTCTCCCCCACCACTTTCAGAGCCCAAGCAAGCCAAGGTAGTGGCCCGAAGGGAGAGCGGGGGCCGCCCCATCAAACCTCCCAAGAAGGACCTGGAAGATGGTGAGGTCCCACAGCACGCGGGTAAAAAGGGAAAACTGTCCGAGCACCTGCGGCACTGTGACAGCATCCTCCGGGAGATGCTGTCCAAGAAGCATGCTGCCTATGCGTGGCCCTTTTACAAGCCAGTGGACGCGGAGGCGCTGGAGCTGCATGACTACCATGACATCATCAAGCACCCCATGGACCTCAGCACGGTCAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026918-'15-16,'15-15,16-16
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.968 A=1.000 C2=0.661
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
PF0043920=Bromodomain=PU(52.8=37.9)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000109574f2027A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000109574





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000028282, ENSMUSP00000076918, ENSMUSP00000114422, ENSMUSP00000115755, ENSMUSP00000128812
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:134049676-134049757 
ALTERNATIVE
HsaEX0008415
(BRD3)
Human
(hg19)
chr9:136914798-136914879 
ALTERNATIVE
HsaEX0008415
(BRD3)
Rat
(rn6)
chr3:6010667-6010745 
LOW PSI
RnoEX0015114
(Brd3)
Cow
(bosTau6)
chr11:104876543-104876624 
LOW PSI
BtaEX0005732
(BRD3)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACCAACCATCACTGCAAACGT

				
R: 
GTGATGGCAGATGTTGTGGGT

				
Band lengths: 
168-247

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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