MmuEX0012662 @ mm9
Exon Skipping
Gene
ENSMUSG00000063681 | Crb1
Description
crumbs homolog 1 (Drosophila) [Source:MGI Symbol;Acc:MGI:2136343]
Coordinates
chr1:141144696-141224923:-
Coord C1 exon
chr1:141224728-141224923
Coord A exon
chr1:141219804-141219943
Coord C2 exon
chr1:141144696-141145652
Length
140 bp
Sequences
Splice sites
3' ss Seq
AAATTTCATTTGCTCTCCAGTTA
3' ss Score
5.1
5' ss Seq
CTGGTAAGT
5' ss Score
10.65
Exon sequences
Seq C1 exon
GCGTGAACTGTGAGTTGGAAATTGATGAATGCAGATCCCAGCCTTGTCTCCACGGTGCCACATGTCAGGACGCTCCAGGGGGCTACTCCTGTGACTGTGCACCTGGATTCCTTGGAGAGCACTGTGAACTCAGCGTTAATGAATGTGAAAGTCAGCCGTGTCTCCATGGAGGTCTATGTGTGGATGGAAGAAACAG
Seq A exon
TTACCACTGTGACTGCACAGGTAGTGGATTCACAGGGATGCACTGTGAGTCCTTGATTCCTCTTTGTTGGTCAAAGCCTTGTCACAACGACGCGACATGTGAAGATACTGTTGACAGCTATATTTGTCACTGCCGGCCTG
Seq C2 exon
GAATTCACTGTGAAGAAGACGTTGATGAATGTTTACTGCACCCTTGCCTAAATGGTGGTACTTGTGAGAACCTGCCTGGGAATTATGCCTGTCACTGTCCCTTTGATGACACTTCTAGGACATTTTATGGAGGAGAAAACTGCTCAGAAATTCTCCTGGGCTGCACTCATCACCAGTGTCTGAACAATGGAAAATGTATCCCTCATTTCCAAAATGGCCAGCATGGATTCACTTGCCAGTGTCTTTCTGGCTATGCGGGGCCCCTGTGTGAAACTGTCACCACACTTTCATTTGGGAGCAATGGCTTCCTATGGGTCACAAGTGGCTCCCATACAGGCATAGGGCCAGAATGTAACATATCCTTGAGGTTTCACACTGTTCAACCAAACGCACTTCTCCTCATCCGAGGCAACAAGGACGTGTCTATGAAGCTGGAGTTGCTGAATGGTTGTGTTCACTTATCAATTGAAGTCTGGAATCAGTTAAAGGTGCTCCTGTCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000063681_MULTIEX1-1/3=C1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(6.5=3.0),PF0000822=EGF=WD(100=47.0),PF0000822=EGF=PU(54.8=25.8)
A:
PF0000822=EGF=PD(41.9=27.1),PF0000822=EGF=PU(78.1=52.1)
C2:
PF0000822=EGF=PD(18.8=1.9),PF0000822=EGF=WD(100=7.8),PF0000822=EGF=WD(100=10.9),PF0221019=Laminin_G_2=WD(100=43.1),PF0000822=EGF=WD(100=9.7)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGAGCACTGTGAACTCAGC
R:
GTGCAGCCCAGGAGAATTTCT
Band lengths:
249-389
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types