Special

MmuEX0013322 @ mm10

Exon Skipping

Gene
ENSMUSG00000022818 | Cyp2ab1
Description
cytochrome P450, family 2, subfamily ab, polypeptide 1 [Source:MGI Symbol;Acc:MGI:3644957]
Coordinates
chr16:20310082-20313169:-
Coord C1 exon
chr16:20313028-20313169
Coord A exon
chr16:20312229-20312416
Coord C2 exon
chr16:20310082-20310223
Length
188 bp
Sequences
Splice sites
3' ss Seq
CCTCACTGAGCTGTCTGCAGAGC
3' ss Score
2.11
5' ss Seq
AAGGTAGGT
5' ss Score
10.29
Exon sequences
Seq C1 exon
GCCATCGATGACCCTGTCTCTACATTCAGTGAGGAGAACCTGATCCAAGTGGTGATCGACCTGTTTCTGGGAGGCACAGACACCACGGCCACCACACTGCACTGGGCACTCATATACCTGGTCCATCACAGAGCCATCCAAG
Seq A exon
AGCGCGTGCAGCAGGAGCTGGATGAGATGCTGGGAGCTGCACAGACCATCTGCTATGAGGACCGAGAGCGACTGCCCTACACCCGTGCTGTCCTCCACGAGGTGCAGCGCCTTAGCAGCGTTGTAGCTGTGGGCGCTGTACGCCAGTGTGTGACTTCCACCTGGATGCATGGTTATTATGTCCCCAAG
Seq C2 exon
GGAACCATCATCCTGCCCAATCTGGCCTCTGTGTTGTATGACCCTGAGTGCTGGGAGAGCCCTCATCAATTCAACCCTGGCCACTTCCTAGACAAGGATGGAAACTTTGTGGCCAACGAGGCCTTCCTGCCCTTCTCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022818-'7-12,'7-11,8-12
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006717=p450=FE(17.5=100)

							
A:
PF0006717=p450=FE(23.1=100)

							
C2:
PF0006717=p450=FE(17.5=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000138133





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000023513
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr3:183904195-183904381 
Human
(hg19)
chr3:183621983-183622169 
Rat
(rn6)
chr11:84510449-84510636 
ALTERNATIVE
RnoEX0025825
(Cyp2ab1)
Cow
(bosTau6)
chr1:83842727-83842910 
Chicken
(galGal4)
chr9:15158254-15158441 
GgaEX6046404
([1])
Chicken
(galGal3)
chr9:16788339-16788526 
GgaEX6046404
(E1C788_CHICK)
Zebrafish
(danRer10)
chr20:25715635-25715758 
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCCATCGATGACCCTGTCTCT

				
R: 
TGGCCACAAAGTTTCCATCCT

				
Band lengths: 
257-445

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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