MmuEX0014892 @ mm10
Exon Skipping
Gene
ENSMUSG00000030409 | Dmpk
Description
dystrophia myotonica-protein kinase [Source:MGI Symbol;Acc:MGI:94906]
Coordinates
chr7:19091939-19093821:+
Coord C1 exon
chr7:19091939-19092036
Coord A exon
chr7:19092208-19092254
Coord C2 exon
chr7:19092950-19093821
Length
47 bp
Sequences
Splice sites
3' ss Seq
CCTCTCTCTTCTCCTTCCAGCCA
3' ss Score
10.88
5' ss Seq
CATGTAAGA
5' ss Score
5.58
Exon sequences
Seq C1 exon
CCAACTACAGGAGGCCGAGGTCCGAAACCGAGACCTGGAGGCGCATGTTCGGCAGCTACAGGAACGGATGGAGATGCTGCAGGCCCCAGGAGCCGCAG
Seq A exon
CCATCACGGGGGTCCCCAGTCCCCGGGCCACGGATCCACCTTCCCAT
Seq C2 exon
ATCCCTAGGCCTGGCCTATCCGAGGCGCGTTGCCTGCTCCTGTTCGCCGCTGCTCTGGCTGCTGCCGCCACACTGGGCTGCACTGGGTTGGTGGCCTATACCGGCGGTCTCACCCCAGTCTGGTGTTTCCCGGGAGCCACCTTCGCCCCCTGAACCCTAAGACTCCAAGCCATCTTTCATTTAGGCCTCCTAGGAAGGTCGAGCGACCAGGGAGCGACCCAAAGCGTCTCTGTGCCCATCGCGCCCCCCCCCCCCCCCCACCGCTCCGCTCCACACTTCTGTGAGCCTGGGTCCCCACCCAGCTCCGCTCCTGTGATCCAGGCCTGCCACCTGGCGGCCGGGGAGGGAGGAACAGGGCTCGTGCCCAGCACCCCTGGTTCCTGCAGAGCTGGTAGCCACCGCTGCTGCAGCAGCTGGGCATTCGCCGACCTTGCTTTACTCAGCCCCGACGTGGATGGGCAAACTGCTCAGCTCATCCGATTTCACTTTTTCACTCTCCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030409_MULTIEX1-1/2=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.897 A=1.000 C2=0.020
Domain overlap (PFAM):
C1:
PF041569=IncA=FE(27.0=100),PF088265=DMPK_coil=PD(47.5=85.3)
A:
PF041569=IncA=PD(1.6=12.5)
C2:
NO
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGGAACGGATGGAGATGCTG
R:
GGTATAGGCCACCAACCCAGT
Band lengths:
142-189
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types