MmuINT0050319 @ mm10
Intron Retention
Gene
ENSMUSG00000030409 | Dmpk
Description
dystrophia myotonica-protein kinase [Source:MGI Symbol;Acc:MGI:94906]
Coordinates
chr7:19091939-19092254:+
Coord C1 exon
chr7:19091939-19092036
Coord A exon
chr7:19092037-19092207
Coord C2 exon
chr7:19092208-19092254
Length
171 bp
Sequences
Splice sites
5' ss Seq
CAGGCGAGT
5' ss Score
2.92
3' ss Seq
CCTCTCTCTTCTCCTTCCAGCCA
3' ss Score
10.88
Exon sequences
Seq C1 exon
CCAACTACAGGAGGCCGAGGTCCGAAACCGAGACCTGGAGGCGCATGTTCGGCAGCTACAGGAACGGATGGAGATGCTGCAGGCCCCAGGAGCCGCAG
Seq A exon
GCGAGTCCCTCACCTGCTTCCAGCCAAGGGGGCACTGGGTGGAGATGGGGGGCATGTTGGGTGTGTGAACCCTCGGGGCAGGGGAGGAGTCCAGGCTGGGGCACCGCAGCCGCGCCACTGCCTTTCTCCTCCATCCTCCACACTCCATACACCTCTCTCTTCTCCTTCCAG
Seq C2 exon
CCATCACGGGGGTCCCCAGTCCCCGGGCCACGGATCCACCTTCCCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030409:ENSMUST00000032568:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.897 A=NA C2=1.000
Domain overlap (PFAM):
C1:
PF041569=IncA=FE(27.0=100),PF088265=DMPK_coil=PD(47.5=85.3)
A:
NA
C2:
PF041569=IncA=PD(1.6=12.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACTACAGGAGGCCGAGGTC
R:
ATGGGAAGGTGGATCCGTGG
Band lengths:
143-314
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types