Special

MmuEX0014963 @ mm9

Exon Skipping

Gene
ENSMUSG00000021879 | Dnahc12
Description
dynein, axonemal, heavy chain 12 [Source:MGI Symbol;Acc:MGI:107720]
Coordinates
chr14:27667955-27672533:+
Coord C1 exon
chr14:27667955-27668147
Coord A exon
chr14:27669639-27669831
Coord C2 exon
chr14:27672361-27672533
Length
193 bp
Sequences
Splice sites
3' ss Seq
AATGTTTCTATCGTTTTTAGACC
3' ss Score
9.32
5' ss Seq
CAGGTGAAA
5' ss Score
5.07
Exon sequences
Seq C1 exon
GTGGTATTGATTGCATCAGACTTGGTGAAGTCATTATTGAATATTCTTTTGATTTTAAATTTTATATCACCACAAAACTGAGAAATCCGCACTACATGCCAGAACTGGCTACAAAAGTGTCTTTGCTCAATTTCATGATAACTCCAGAAGGGCTTGAAGATCAATTACTGGGCATTGTTGTTGCAAAGGAGAG
Seq A exon
ACCAGAATTAGAGGAGGAGCGAAATGCCCTCATTCTTCAGTCTGCAGCTAACAAGAAGCAGCTCAAAGATATAGAGACAAAGATTTTAGAAACATTATCGTCTTCAGAAGGGAACATTTTGGAAGATGAAAGTGCAATAAAAGTCTTAGACTCTGCCAAAATTATGTCTAATGAGATCACGAAGAAACAGCAG
Seq C2 exon
GTTGCAGAAAAAACAGAGCTCAAAATAGCAGAGTCGCGAGAAGGATACAGGCCCATCGCCAAACATTCCTCAGTGCTATTCTTTAGCATTGCAGACCTGGCCAACATTGATCCCATGTACCAGTACTCTCTCACCTGGTTTGTGAACCTTTACATCAACTCCATTCATGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000021879-'52-54,'52-53,53-54
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127812=AAA_9=FE(27.7=100)

							
A:
PF127812=AAA_9=PD(26.0=92.3)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000130609





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr3:57363594-57363786 
ALTERNATIVE
HsaEX1011879
(DNAH12)
Human
(hg19)
chr16:20975372-20975563 
Rat
(rn6)
chr16:2501044-2501236 
ALTERNATIVE
RnoEX0028464
(Dnah12)
Cow
(bosTau6)
chr22:44339818-44340010 
HIGH PSI
BtaEX6094423
([1])
Chicken
(galGal4)
chr12:8652114-8652306 
HIGH PSI
GgaEX6010301
([2])
Chicken
(galGal3)
chr12:8899492-8899684 
HIGH PSI
GgaEX6010301
([3])
Zebrafish
(danRer10)
chr23:19592384-19592576 
HIGH PSI
DreEX6079845
(dnah12)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CACCACAAAACTGAGAAATCCGC

				
R: 
ATGGGATCAATGTTGGCCAGG

				
Band lengths: 
242-435

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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