Special

MmuEX0014990 @ mm10

Exon Skipping

Gene
ENSMUSG00000005237 | Dnah2
Description
dynein, axonemal, heavy chain 2 [Source:MGI Symbol;Acc:MGI:107731]
Coordinates
chr11:69517017-69518467:-
Coord C1 exon
chr11:69518276-69518467
Coord A exon
chr11:69517571-69517728
Coord C2 exon
chr11:69517017-69517104
Length
158 bp
Sequences
Splice sites
3' ss Seq
GGACGTTGCTCTCTCTGCAGATG
3' ss Score
9.4
5' ss Seq
CCAGTAGGA
5' ss Score
1.81
Exon sequences
Seq C1 exon
GATGGCTCTCGACAAGCTCAGTCCAACCTGACTTTCTTGTCCATCCTGAGGGAACCCTACCAGGAGTTGGCCTTCATGAAGCCTAAGGACATCTCTGAGAAGCTCCCGAAGCTGATCAGCCTCATCCGAATCATCTGGGTCAACTCCCCCCACTACAACACTCGGGAAAGGCTGACGGCGCTGTTCCGGAAG
Seq A exon
ATGAGCAACGAGATCATCCGTTTATGCTGTCACTCCATCTCTTTGGACCGAATCTTTGAGGGCTATGTCAATTCTAGCAAGGAGGACCTGGAAGGCTGCATTTCCTGTTGTCAGGCTTGGAAAGAGCACTACCTGCGTGCCGTACAGATGCACACCCA
Seq C2 exon
GTTCTCCAATCGGGGCTGGGTTCTGGACCAGACGAGCATATTTGCTCAAGTAGATGCCTTTGTGCAGCGCTGCAAAGACCTTATTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000005237_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
In the CDS, with uncertain impact





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.002 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF083857=DHC_N1=PU(15.9=97.4)

							
A:
PF083857=DHC_N1=FE(22.4=100)

							
C2:
PF083857=DHC_N1=FE(12.5=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000146424





     
                   









    
Main Skipping Isoform:
ENSMUSP00000104299





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr17:7737963-7738056 
ALTERNATIVE
HsaEX6020699
(DNAH2)
Human
(hg19)
chr17:7641281-7641438 
ALTERNATIVE
HsaEX6020699
(DNAH2)
Rat
(rn6)
chr10:56121794-56121870 
HIGH PSI
RnoEX0028529
(Dnah2)
Cow
(bosTau6)
chr19:28047044-28047201 
BtaEX0011590
(DNAH2)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr7:21091623-21091780 
HIGH PSI
DreEX0003665
(DNAH2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CTCGACAAGCTCAGTCCAACC

				
R: 
CGCTGCACAAAGGCATCTACT

				
Band lengths: 
254-412

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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