MmuEX0023582 @ mm10
Exon Skipping
Gene
ENSMUSG00000030541 | Idh2
Description
isocitrate dehydrogenase 2 (NADP+), mitochondrial [Source:MGI Symbol;Acc:MGI:96414]
Coordinates
chr7:80098998-80103213:-
Coord C1 exon
chr7:80103122-80103213
Coord A exon
chr7:80100743-80100908
Coord C2 exon
chr7:80098998-80099158
Length
166 bp
Sequences
Splice sites
3' ss Seq
ACTCTGGCCTTCTTCCCTAGCTC
3' ss Score
8.16
5' ss Seq
AAGGTATGA
5' ss Score
9.11
Exon sequences
Seq C1 exon
ATGCTGAGAAGAGGATCAAGGTGGAGAAGCCGGTAGTGGAGATGGACGGTGACGAGATGACCCGGATCATCTGGCAGTTCATCAAGGAGAAG
Seq A exon
CTCATCCTGCCTCACGTGGATGTTCAGCTCAAGTATTTTGACCTTGGGCTTCCAAACCGTGACCAGACCAATGACCAGGTCACCATTGACTCTGCTCTGGCCACCCAGAAGTACAGTGTGGCTGTCAAGTGTGCCACAATCACCCCTGATGAGGCCCGTGTGGAAG
Seq C2 exon
AGTTCAAGCTGAAGAAAATGTGGAAGAGCCCTAACGGAACGATCCGGAACATCCTTGGGGGAACCGTCTTCAGAGAGCCAATCATCTGCAAAAACATCCCCCGCCTTGTCCCTGGCTGGACCAAGCCCATCACCATTGGCAGGCACGCCCATGGCGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030541-'14-8,'14-5,17-8
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.065 A=0.060 C2=0.000
Domain overlap (PFAM):
C1:
PF0018015=Iso_dh=PU(11.7=77.4)
A:
PF0018015=Iso_dh=FE(13.9=100)
C2:
PF0018015=Iso_dh=FE(13.4=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGAGAAGAGGATCAAGGTGG
R:
ATGGGCGTGCCTGCCAAT
Band lengths:
242-408
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types