MmuEX0026863 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:40882140-40889344:-
Coord C1 exon
chr2:40889222-40889344
Coord A exon
chr2:40886641-40886760
Coord C2 exon
chr2:40882140-40882268
Length
120 bp
Sequences
Splice sites
3' ss Seq
TAATCATCTTTGTTCATTAGATT
3' ss Score
5.44
5' ss Seq
GTGGTGAGC
5' ss Score
6.64
Exon sequences
Seq C1 exon
TTCAAAACAAACACAAATGTGAAGAGAATTATTTTGGTTGTCCTAGTGGAAGATGCATTTTGAATACCTGGGTATGTGATGGTCAGAAGGACTGCGAGGACGGGCTGGATGAGCTACACTGTG
Seq A exon
ATTCTTCTTGCTCTTGGAATCAATTTGCTTGTTCTGTAAAAAAATGTATTTCTAAACACTGGATCTGTGATGGAGAGGATGACTGTGGAGACAGCTTAGATGAAAGTGACAGCATTTGTG
Seq C2 exon
GTGCAGTCACTTGTGCTGCTGACATGTTCAGCTGCCAGGGCTCCCATGCCTGTGTGCCCCAACACTGGCTGTGTGATGGTGAGAGAGACTGTCCCGACGGGAGTGATGAGCTATCCAGTGCAGGCTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'78-77,'78-76,79-77
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=88.1)
A:
PF0005713=Ldl_recept_a=WD(100=95.1)
C2:
PF0005713=Ldl_recept_a=WD(100=93.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGAAGAGAATTATTTTGGTTGTCC
R:
CACAGCCTGCACTGGATAGC
Band lengths:
235-355
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types