MmuEX0026867 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41506645-41671063:-
Coord C1 exon
chr2:41670901-41671063
Coord A exon
chr2:41511405-41511627
Coord C2 exon
chr2:41506645-41506816
Length
223 bp
Sequences
Splice sites
3' ss Seq
ATTTACTTTTCTTTCAACAGAAA
3' ss Score
9.96
5' ss Seq
CAGGTAAGT
5' ss Score
10.86
Exon sequences
Seq C1 exon
ATGTGGAACAAATGGCATTTGACTGGCTTACCAGAAATATCTACTTCGTGGACCATGTCAGTGACCGGATCTTTGTTTGTAATTTCAATGGCTCTGTGTGTGTCACTCTGATTGAATCGGAGCTTCACAATCCTAAGGCCATAGCAGCAGATCCCATCGCAGG
Seq A exon
AAAACTTTTCTTTACTGACTATGGGAATGTTCCCAAAATAGAGAGATGTGACTTGGATGGGATGAACAGAACAAGGATAGTTTATTCAAAGGCAGAGCAGCCATCGGCCCTAGCTTTGGACCTCGTCAACAGATTGGTTTATTGGGTAGATCTCTACTTGGACTACGTGGGAGTAGTAGACTACCAAGGCAAAAACAGGCATACAATTGTTCAAGGCAGACAG
Seq C2 exon
GTTAAACATCTCTATGGCATAACTGTATTTGAAGATTATTTATATGCAACCAGTTCTGATAACTTCAATATCATACGAATAAACAGATTTAATGGCACTGATATTCACTCAATAATTAAAATGGAGAGTGCTCGAGGAATCCGAACCTATCAGAAGAGAACACAGCCAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'21-18,'21-17,23-18
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.052
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=74.5)
A:
PF0005812=Ldl_recept_b=PU(71.4=40.0)
C2:
PF0005812=Ldl_recept_b=PD(23.8=17.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCATTTGACTGGCTTACCA
R:
TTCGGATTCCTCGAGCACTCT
Band lengths:
296-519
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types