Special

MmuEX0027252 @ mm9

Exon Skipping

Gene
ENSMUSG00000002020 | Ltbp2
Description
latent transforming growth factor beta binding protein 2 [Source:MGI Symbol;Acc:MGI:99502]
Coordinates
chr12:86140322-86145435:-
Coord C1 exon
chr12:86145307-86145435
Coord A exon
chr12:86144737-86144865
Coord C2 exon
chr12:86140322-86140441
Length
129 bp
Sequences
Splice sites
3' ss Seq
CCCTGCTTCCTTCTGGTCAGATG
3' ss Score
7.78
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
ACTTTGATCCATGTTTTGCTGGAGCCTCCAACATCTGTGGCCCTGGGACCTGTGTGAGCCTCCCAAATGGATACAGATGTGTCTGCAGCCCTGGCTACCAGCTACACCCCAGCCAAGACTACTGTACTG
Seq A exon
ATGACAACGAGTGTATGAGGAACCCCTGTGAAGGAAGAGGGCGCTGTGTCAACAGTGTGGGCTCCTACTCCTGCCTCTGCTATCCTGGCTACACACTAGTCACCCTCAGAGACACACAGGAGTGCCAAG
Seq C2 exon
ATATCGATGAGTGTGAGCAGCCCGGGGTGTGCAGTGGTGGGCGATGCAGCAACACGGAGGGCTCGTACCACTGCGAGTGTGATCGGGGCTACATCATGGTCAGGAAAGGACACTGTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000002020-'19-17,'19-16,20-17=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF062476=Plasmod_Pvs28=PU(28.8=81.8),PF146701=FXa_inhibition=WD(100=79.5),PF0764510=EGF_CA=PU(0.1=0.0)

							
A:
PF0764510=EGF_CA=WD(100=95.5),PF0764510=EGF_CA=PU(0.1=0.0)

							
C2:
PF062476=Plasmod_Pvs28=FE(32.0=100),PF0764510=EGF_CA=WD(100=95.1),PF0764510=EGF_CA=PU(0.1=0.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000128882





     
                   









    
Main Skipping Isoform:
ENSMUSP00000105883





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000002073, ENSMUSP00000128882f99A
          









    
Other Skipping Isoforms:
ENSMUSP00000127693
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr14:74521911-74522039 
HIGH PSI
HsaEX6072156
(LTBP2)
Human
(hg19)
chr14:74988614-74988742 
HIGH PSI
HsaEX6072156
(LTBP2)
Rat
(rn6)
chr6:108524525-108524653 
HIGH PSI
RnoEX6029359
(Ltbp2)
Cow
(bosTau6)
chr10:86209521-86209649 
HIGH PSI
BtaEX6055042
(LTBP2)
Chicken
(galGal4)
chr5:37222647-37222775 
HIGH PSI
GgaEX6038601
(LTBP2)
Chicken
(galGal3)
chr5:40351443-40351571 
HIGH PSI
GgaEX6038601
(LTBP2)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCCATGTTTTGCTGGAGCCTC

				
R: 
CTTGACAGTGTCCTTTCCTGACC

				
Band lengths: 
242-371

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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