MmuEX0028104 @ mm10
Exon Skipping
Gene
ENSMUSG00000022139 | Mbnl2
Description
muscleblind-like 2 [Source:MGI Symbol;Acc:MGI:2145597]
Coordinates
chr14:120396451-120431697:+
Coord C1 exon
chr14:120396451-120396604
Coord A exon
chr14:120404638-120404732
Coord C2 exon
chr14:120428935-120431697
Length
95 bp
Sequences
Splice sites
3' ss Seq
CATGGTTCCCCTCCTGAAAGTAC
3' ss Score
3.97
5' ss Seq
CAGGTTTGC
5' ss Score
4.86
Exon sequences
Seq C1 exon
GCCTTCCCTCCGGGTGCTCTTCATCCCTTACCAAAGAGACAAGCACTTGAAAAAAGCAACGGGGCCAGCACGGTCTTCAACCCCAGCGTCTTGCACTACCAGCAGGCTCTGACCAGTGCGCAGCTGCAGCAGCACACGGCGTTCATCCCCACAG
Seq A exon
TACCCATGATGCACAGCGCTACGTCCGCCACTGTCTCTGCAGCAACAACTCCTGCAACAAGTGTCCCCTTCGCAGCAACAGCCACAGCCAATCAG
Seq C2 exon
ATAATTCTGAAATAATCAACAGAAATGGAATGGAATGCCAAGAATCTGCATTGAGAATAACTAAACATTGTTACTGTACATATTACCCCGTTTCCTCCTCAATAGAATTGCCACAAACTGCATGCTAAATTTAGTTCTTCTGGACAGACCACAACCCTAAGGCTAGTTCTGCTATGTCATATATGAGTATTAAATATGGTATGCTTAGTATACTCCAGCCTAAGATAGTTAACCACCTGAGACCAGCTGTGATGTTCGAAGACATACAGGATGAGGTTTTCTTTCACAGGGTTCTGAGCATAGTTTCTGTCCCAGGAATATTGTCTTATCTCCATAACTATAGCTGATGCAGAAAGTCCAGACAATATACTCATTTCGACTCAGAATATTTCAAATTTAGCAATAAACAGTTAGCTTTAGTTTTAAGTACCTATTCCAAGGGCAGGTTCGATTGTAACTCCAATCACAACCATTTCATTTCCTGACTGGATCGAAGGGTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022139_MULTIEX2-6/6=4-C2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (disopred):
C1=0.188 A=1.000 C2=0.812
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACCAGCAGGCTCTGACCAG
R:
GCATGCAGTTTGTGGCAATTCT
Band lengths:
183-278
Functional annotations
There are 1 annotated functions for this event
PMID: 27733504
The presence of alternative ex.54nt always significantly elevated MBNL1 and MBNL2 protein levels (_2... [Show more]
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types