MmuEX0028103 @ mm10
Exon Skipping
Gene
ENSMUSG00000022139 | Mbnl2
Description
muscleblind-like 2 [Source:MGI Symbol;Acc:MGI:2145597]
Coordinates
chr14:120396451-120431697:+
Coord C1 exon
chr14:120396451-120396604
Coord A exon
chr14:120403336-120403371
Coord C2 exon
chr14:120428935-120431697
Length
36 bp
Sequences
Splice sites
3' ss Seq
CCCCCATTGCATGACTTCAGGGT
3' ss Score
6.56
5' ss Seq
TTGGTAGGT
5' ss Score
7.03
Exon sequences
Seq C1 exon
GCCTTCCCTCCGGGTGCTCTTCATCCCTTACCAAAGAGACAAGCACTTGAAAAAAGCAACGGGGCCAGCACGGTCTTCAACCCCAGCGTCTTGCACTACCAGCAGGCTCTGACCAGTGCGCAGCTGCAGCAGCACACGGCGTTCATCCCCACAG
Seq A exon
GGTCAGTTTTGTGCATGACACCCGCTACCAGTATTG
Seq C2 exon
ATAATTCTGAAATAATCAACAGAAATGGAATGGAATGCCAAGAATCTGCATTGAGAATAACTAAACATTGTTACTGTACATATTACCCCGTTTCCTCCTCAATAGAATTGCCACAAACTGCATGCTAAATTTAGTTCTTCTGGACAGACCACAACCCTAAGGCTAGTTCTGCTATGTCATATATGAGTATTAAATATGGTATGCTTAGTATACTCCAGCCTAAGATAGTTAACCACCTGAGACCAGCTGTGATGTTCGAAGACATACAGGATGAGGTTTTCTTTCACAGGGTTCTGAGCATAGTTTCTGTCCCAGGAATATTGTCTTATCTCCATAACTATAGCTGATGCAGAAAGTCCAGACAATATACTCATTTCGACTCAGAATATTTCAAATTTAGCAATAAACAGTTAGCTTTAGTTTTAAGTACCTATTCCAAGGGCAGGTTCGATTGTAACTCCAATCACAACCATTTCATTTCCTGACTGGATCGAAGGGTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022139_MULTIEX2-5/6=4-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (disopred):
C1=0.188 A=0.846 C2=0.812
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENSMUST00000088419fB2389
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTCTTGCACTACCAGCAGG
R:
GCAGATTCTTGGCATTCCATTCC
Band lengths:
117-153
Functional annotations
There are 1 annotated functions for this event
PMID: 21454535
Inferred from MBNL1 ortholog: The exon 7 region enhances MBNL1-MBNL1 dimerization properties
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types