DreEX0045310 @ danRer10
Exon Skipping
Gene
ENSDARG00000018460 | mbnl2
Description
muscleblind-like splicing regulator 2 [Source:ZFIN;Acc:ZDB-GENE-030131-9582]
Coordinates
chr1:2053666-2057967:+
Coord C1 exon
chr1:2053666-2053822
Coord A exon
chr1:2056022-2056057
Coord C2 exon
chr1:2057873-2057967
Length
36 bp
Sequences
Splice sites
3' ss Seq
TCTTCACTGCATGGTCACAGGGT
3' ss Score
4.54
5' ss Seq
TTGGTAGGT
5' ss Score
7.03
Exon sequences
Seq C1 exon
GCGTTTCCGCATGGAGTCCTGCAGCCCCTACCAAAGAGACCAGCACTAGAAAAGAGTAACGGGGCCAGCACGCTCTTCAACCCCAGTGTCTTGCACTACCAACAGGCTTTGGCCAGCGCACAGCTTCAGCAGCCCACCGCTGCGTTCTTTCCCACAG
Seq A exon
GGTCAGTTCTGTGCATGGCTCCTGCTAGCAGCATTG
Seq C2 exon
TACCCATGATGTACAGTGCTACGCCTGCTACTGTCTCTGCAGCAACAACTCCTGCCACAAGTGTCCCCTACGCAACAACAGCACCAGCCAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000018460_MULTIEX2-1/2=C1-2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (disopred):
C1=0.759 A=1.000 C2=0.971
Domain overlap (PFAM):
C1:
PF149201=MTBP_C=PD(0.7=1.9)
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCTTGCACTACCAACAGGC
R:
GGAGTTGTTGCTGCAGAGACA
Band lengths:
123-159
Functional annotations
There are 1 annotated functions for this event
PMID: 21454535
Inferred from MBNL1 ortholog: The exon 7 region enhances MBNL1-MBNL1 dimerization properties
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]