RnoEX0053023 @ rn6
Exon Skipping
Gene
ENSRNOG00000010737 | Mbnl2
Description
muscleblind-like splicing regulator 2 [Source:RGD Symbol;Acc:1591755]
Coordinates
chr15:105764135-105797932:+
Coord C1 exon
chr15:105764135-105764288
Coord A exon
chr15:105770992-105771027
Coord C2 exon
chr15:105795144-105797932
Length
36 bp
Sequences
Splice sites
3' ss Seq
CCCCCATTGCATGACTTCAGGGT
3' ss Score
6.56
5' ss Seq
TTGGTAGGT
5' ss Score
7.03
Exon sequences
Seq C1 exon
GCCTTCCCTCCCGGTGCTCTTCACCCTTTACCAAAGAGACAAGCACTTGAAAAAAGCAACGGAGCCAGCACGGTCTTCAACCCCAGCGTCTTGCACTACCAGCAGGCTTTGACCAGTGCGCAGTTGCAGCAACACACGGCGTTCATTCCCACAG
Seq A exon
GGTCAGTTTTGTGCATGACACCCGCTACCAGTATTG
Seq C2 exon
ATAATTCTGAAATAATCAACAGAAATGGAATGGAATGCCAAGAATCTGCATTGAGAATAACTAAACATTGTTACTGTACATACTATCCCCTTTGCTCCTCAATAGAATTGCCACAAACTGCATGCTAAATTTAGTTCTTCCGGACAGACCGCAACCCTAAGGCTAGTTCTGCTATGTCATATACGAGTATTAAATATGGTATGCTTAGTATATTCCAGCCTAAGATAGTTAACTACCTGAGACCAGCTGCGATGTTCAAAGACATACAGGATGAGGTTTTCTTTTACAGGGTTCTGAGCGTAGTTTCTGTCCCAGGAATATTGTCTTATCTCCATAACTATAGCCGATGCAGAAAGCCCACCCAGTATACACATTTCGACTCAGAATACTTCAAATTTAGCAATAAGCAGTTAGCTTTAGTTTAAGTACCTATTCCAAGGGCAGGTTCGATTCTAATTCCAATCACCACCATTTCATTTCCTGACTGGATCATAAGGGTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000010737_MULTIEX2-1/2=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (disopred):
C1=NA A=NA C2=NA
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENSRNOT00000014300fB8466
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTGCACTACCAGCAGGCTTT
R:
GCAGATTCTTGGCATTCCATTCC
Band lengths:
114-150
Functional annotations
There are 1 annotated functions for this event
PMID: 21454535
Inferred from MBNL1 ortholog: The exon 7 region enhances MBNL1-MBNL1 dimerization properties
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]