MmuEX0028280 @ mm9
Exon Skipping
Gene
ENSMUSG00000039842 | Mcph1
Description
microcephaly, primary autosomal recessive 1 [Source:MGI Symbol;Acc:MGI:2443308]
Coordinates
chr8:18629546-18641665:+
Coord C1 exon
chr8:18629546-18629635
Coord A exon
chr8:18631516-18632643
Coord C2 exon
chr8:18641565-18641665
Length
1128 bp
Sequences
Splice sites
3' ss Seq
TTCTTTGTTGATCTCTGCAGATG
3' ss Score
10.39
5' ss Seq
AAAGTATGT
5' ss Score
6.93
Exon sequences
Seq C1 exon
CCTCCCAGATGTTGGAGCAGTCTCAGCAGAATCCATGTGTCAGTCTGTTTGAAACATCCTTGAACATTTCTCACCAACCTTTGAGTTCAG
Seq A exon
ATGAATCCTTTGCCAGTGGCTCCCACTCATCTTTCGGTGATTCCTGTGGAGATCAAGAAAGGAAACTGGGAAGATCTGCTAATGAGATGACCACGGTGACATGCCCTTCCTCACCTGTGTTGAGGGCAAGCAGTTTTTATGGCTCAGCATCACCCAACCATCTCAGGCAGCCACGTCCTCAGAAAGCTCCAGACAGTCCTTCAAAGGAGAGCATCAACTGTCAGAAGGATGCTACAGGTGCGGTAGCTGATTCCGAGAGAAAGCAAGCTGCAGGTGTATCTCAGGGGGTGCCTGATGAGAAGCTCTGTCTGTCTCCTACGATGTCCATCATAGAAGAACACCAAGTACGGTTGGGACCCAAGAATTCTTCTGCAAAGAGAAAAAGGGCAGCGGACTTGGGTTCATCTCCAAAAGGAAAACTGAAGAAGAGGTACAAGAGAAAGTCTGCTCTGGCAATACAGTTATTCAAGTCCGACCAGAGCCCGCCGTCCACAATCAGACTCATTCCGGGAACTCCTGACGTTGAGGCTTCTTCCTATGAGGACTATTTTTCCCCTGATAATCTCAAGGAGAGGAATTCGGAGAGACTTCCTCCTGAGGCTCAGCAACTAGCAAGCCCTTCTCTGTTCCACTGCAGAGGTCTCTCAAAGTGGGAGCGAAGAAACATGCTGGAAATGTGTGATTTTACCTGCATTGGTGAAAAGCACAGATCCATCAGCAGCATTAGTGACTTAATTTCAAAAAGTGCCTCTAGTCTTGAGAAACCTGTCAAGGAGGAAGTGAATACAGCTTCTACCTGCTTGCTTTTGGTGGAGACCTCTGCTAACGACAGCCCAGGGCTTTGCAGTCAGCCTGGCCCTCAGCTGAGGGATGACACAGGCCCAGAGGGAAGCAGCCACCCTGACACCCTGTCTAGTTCTGCCCACCACATCACACCCTTGAAAGGAAATAGTACAGAAACCAGAGACCCAGGTGATGGAAAAGGCTCCCCCAAAGAAGGTAGCACGCCTCCTGCATCAGCCTCTCCTGAAGATGAAGTACACATCTGTAATCTCAGTTTGGGAGAGGATTGTAATGTAGAAAAGTCTGTAGAAGAAAAGGAGAACATAGCCACAGGATATAGTGAAA
Seq C2 exon
GTGTTAAAAATGGACCAGGGCGGCCAGATCCTTCAGACAGCTCTTGCACAGGCCTTGTCAGACCTCAGCAGAAACCAAAGAAAAGTGAGAAAGAAGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039842_MULTIEX1-4/5=3-5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show structural model
Features
Disorder rate (Iupred):
C1=0.476 A=0.737 C2=0.931
Domain overlap (PFAM):
C1:
NO
A:
PF122583=Microcephalin=WD(100=99.5)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGATGTTGGAGCAGTCTCAGC
R:
TTCTTCTTTCTCACTTTTCTTTGGT
Band lengths:
182-1310
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types