Special

MmuEX0030538 @ mm10

Exon Skipping

Gene
ENSMUSG00000033590 | Myo5c
Description
myosin VC [Source:MGI Symbol;Acc:MGI:2442485]
Coordinates
chr9:75257959-75263125:+
Coord C1 exon
chr9:75257959-75258224
Coord A exon
chr9:75262208-75262289
Coord C2 exon
chr9:75262985-75263125
Length
82 bp
Sequences
Splice sites
3' ss Seq
TTTGTTCAACTGTGTTTCAGTTT
3' ss Score
8.63
5' ss Seq
CTGGTAGGT
5' ss Score
8.37
Exon sequences
Seq C1 exon
GAGGATGACAGTCACCTGAAGGTGTTCTGTGAGCTCTTGGGCCTGGAGACCAGCAAAGTGGCTCAGTGGCTGTGCAACAGAAAAATTGTGACCTCCTCGGAAACTGTGGTAAAGCCCATGACCAGGCCTCAGGCCATCAACGCCAGGGATGCGCTGGCCAAAAAGATCTACGCTCACCTGTTCGACTTCATTGTCGAGCAAATCAACCAGGCGTTGCACTTCTCAGGCAAGCAGCACACTTTTATTGGTGTTTTGGACATTTATGG
Seq A exon
TTTTGAGACCTTTGATGTAAACAGCTTTGAACAGTTCTGCATCAATTACGCTAATGAAAAACTACAGCAGCAGTTTAACCTG
Seq C2 exon
CACGTCTTTAAACTTGAGCAAGAGGAATACATGAAAGAGGACATCCCCTGGACTCTGATAGACTTCTATGACAACCAGCCTGTTATTGACCTGATCGAGGCAAAAATGGGCATTTTGGAGTTGCTGGATGAAGAATGCTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033590-'24-16,'24-15,27-16=AN
Average complexity
A_C1
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006316=Myosin_head=FE(13.1=100)

							
A:
PF0006316=Myosin_head=FE(4.0=100)

							
C2:
PF0006316=Myosin_head=FE(6.8=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000042229





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr15:52256639-52256720 
HIGH PSI
HsaEX6074810
(MYO5C)
Human
(hg19)
chr15:52548836-52548917 
HIGH PSI
HsaEX6074810
(MYO5C)
Rat
(rn6)
chr8:82203519-82203600 
ALTERNATIVE
RnoEX0057421
(Myo5c)
Cow
(bosTau6)
chr10:58212760-58212841 
HIGH PSI
BtaEX6053685
(MYO5C)
Chicken
(galGal4)
chr10:8343131-8343212 
HIGH PSI
GgaEX6007796
(MYO5C)
Chicken
(galGal3)
chr10:10099923-10100004 
HIGH PSI
GgaEX6007796
([1])
Zebrafish
(danRer10)
chr25:7462124-7462205 
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GATGCGCTGGCCAAAAAGATC

				
R: 
ATCAGAGTCCAGGGGATGTCC

				
Band lengths: 
178-260

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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