MmuEX0031325 @ mm10
Exon Skipping
Gene
ENSMUSG00000026950 | Neb
Description
nebulin [Source:MGI Symbol;Acc:MGI:97292]
Coordinates
chr2:52183732-52187515:-
Coord C1 exon
chr2:52187411-52187515
Coord A exon
chr2:52186012-52186116
Coord C2 exon
chr2:52183732-52183836
Length
105 bp
Sequences
Splice sites
3' ss Seq
TTAATATGATGTTTGAGCAGAAA
3' ss Score
3.6
5' ss Seq
CAGGTACTG
5' ss Score
9.04
Exon sequences
Seq C1 exon
TATAAGTATAAAGAAGTATTTGAAAGAACAAAGTCAAACTTCAAGTATGTTGCTGACTGTCCAATTAACAGGCATTTCAAGTATGCAACTCAGTTGATGAATGAG
Seq A exon
AAAAAATACAGAGCTGATTATGAGCAGCGGAAAGATAAATACCACCTGGTAGTCGATGAACCTAGACATCTGCTGGCTAAGACCGCAGGCGACCAGATCAGCCAG
Seq C2 exon
ATCAAATACAGGAAAAAGTATGAGAAGTCAAAGGACAAATTCACCTCGGTTGTGGACACCCCAGAGCACCTGCGCACCACAAAAGTCAACAAGCAAATCAGTGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026950-'136-148,'136-145,137-148
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.057
Domain overlap (PFAM):
C1:
PF0088013=Nebulin=PD(37.9=31.4),PF0088013=Nebulin=PU(55.2=45.7)
A:
PF0088013=Nebulin=PD(37.9=31.4),PF0088013=Nebulin=PU(55.2=45.7)
C2:
PF0088013=Nebulin=PD(37.9=31.4),PF0088013=Nebulin=PU(55.2=45.7)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAAGAACAAAGTCAAACTTCAAGT
R:
CTGATTTGCTTGTTGACTTTTGTGG
Band lengths:
186-291
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types