Special

MmuEX0035986 @ mm10

Exon Skipping

Gene
ENSMUSG00000026926 | Pmpca
Description
peptidase (mitochondrial processing) alpha [Source:MGI Symbol;Acc:MGI:1918568]
Coordinates
chr2:26391084-26392675:+
Coord C1 exon
chr2:26391084-26391178
Coord A exon
chr2:26391866-26391966
Coord C2 exon
chr2:26392412-26392675
Length
101 bp
Sequences
Splice sites
3' ss Seq
CCTTGTCTGGACTCTTGCAGATG
3' ss Score
8.91
5' ss Seq
GAAGTAAAA
5' ss Score
0.12
Exon sequences
Seq C1 exon
AGACACCACCATGTATGCTGTGTCTGCTGACAGCAAAGGCTTGGACACTGTGGTGGATCTGTTGGCTGATGTGGTTCTGCACCCCCGACTGACAG
Seq A exon
ATGAAGAAATTGAGATGACGAGGATGGCTGTGCAGTTTGAACTAGAGGACCTGAACATGAGACCTGACCCAGAGCCACTGCTCACCGAGATGATTCATGAA
Seq C2 exon
GCTGCTTTTAGGGAGAACACAGTGGGTCTGCACCGGTTCTGCCCTGTAGAGAACATAGCGAAGATCGATCGGGAAGTGCTGCACTCCTACCTAAAGAACTACTACACCCCTGACCGCATGGTGCTTGCTGGGGTGGGCGTGGAGCATGAGCACCTAGTAGAATGTGCCAGAAAGTACCTCGTGGGAGCCGAGCCTGCCTGGGGAGCCCCTGGAACGGTGGACGTTGACAGATCAGTGGCACAGTACACTGGGGGGATCATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026926-'9-15,'9-13,13-15=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.059 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0067515=Peptidase_M16=FE(21.2=100)

							
A:
PF0067515=Peptidase_M16=FE(21.9=100)

							
C2:
PF0067515=Peptidase_M16=PD(9.9=17.0),PF0519316=Peptidase_M16_C=PU(33.5=76.1)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000075762





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000109727
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr9:136416291-136416391 
HIGH PSI
HsaEX6064020
(PMPCA)
Human
(hg19)
chr9:139310743-139310843 
HIGH PSI
HsaEX6064020
(PMPCA)
Rat
(rn6)
chr3:3836799-3836899 
HIGH PSI
RnoEX0067594
(Pmpca)
Cow
(bosTau6)
chr11:103921287-103921387 
HIGH PSI
BtaEX6047192
(PMPCA)
Chicken
(galGal4)
chr17:7888190-7888290 
HIGH PSI
GgaEX1044769
(PMPCA)
Chicken
(galGal3)
chr17:8577289-8577389 
HIGH PSI
GgaEX1044769
(Q5ZJ49_CHICK)
Zebrafish
(danRer10)
chr5:64358662-64358762 
HIGH PSI
DreEX0056599
(pmpca)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CAAAGGCTTGGACACTGTGGT

				
R: 
CCACGAGGTACTTTCTGGCAC

				
Band lengths: 
246-347

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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