Special

MmuEX0038678 @ mm10

Exon Skipping

Gene
Description
Ral GEF with PH domain and SH3 binding motif 2 [Source:MGI Symbol;Acc:MGI:1925505]
Coordinates
chr1:156887947-156900636:-
Coord C1 exon
chr1:156900586-156900636
Coord A exon
chr1:156892908-156893012
Coord C2 exon
chr1:156887947-156888030
Length
105 bp
Sequences
Splice sites
3' ss Seq
TTCTCTGCTTCTGTCTATAGGTA
3' ss Score
11.86
5' ss Seq
AGGGTAGGT
5' ss Score
8.1
Exon sequences
Seq C1 exon
GGTCAGATAACACTAATGGATGTTCCAGTGTTTAAAGCTATTCAGCCAGAT
Seq A exon
GTATCCCTACATCATCACCCTTAGAACAGTCCTTTTAAGAGTGTTGGAACCTACAAGACGTAAGAGAAGCTGTGACTCCTGTGAATTGAGTCATTCTCTCATAGG
Seq C2 exon
GAACTTTCAAGTTGTGGATGGAATAAAAAAGAAAAATATAGTTCTGCACCAAATGCAGTTGCTTTCACAAGAAGATTTAATCAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026594_MULTIEX1-4/4=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence inclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.429 C2=0.000
Domain overlap (PFAM):

C1:
PF0061714=RasGEF=FE(19.3=100)
A:
NO
C2:
PF0061714=RasGEF=FE(13.8=100)


Main Inclusion Isoform:


Main Skipping Isoform:


Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTCAGATAACACTAATGGATGTTCC
R:
TAAATCTTCTTGTGAAAGCAACTGCA
Band lengths:
130-235
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types